The 2021 Freightliner Sprinter 2500 has 41 cooling system parts with verified fitment on this page — 12 part types and 15 brands, covering all 3 engine options (2.0L L4 Turbocharged, 2.1L L4 DIESEL Turbocharged and 3.0L V6 DIESEL Turbocharged). Each part includes a manufacturer part number and application notes.
On the 2021 Freightliner Sprinter 2500, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Coolant / Antifreeze (16 parts), Water Pump (7 parts) and Radiator Hose (4 parts). The other 9 part types cover the remaining 14 parts.
The 2021 Freightliner Sprinter 2500 was sold with 3 engines. 15 parts fit every engine; the other 26 are engine-specific. Each part shows which engine(s) it fits.
The most listed brands for 2021 Freightliner Sprinter 2500 cooling system parts are REIN (8 parts), PRESTONE (5 parts) and PEAK (5 parts), plus 12 more brands. Quality grades include Standard Replacement, Economy and Premium.
5 parts on this 2021 Freightliner Sprinter 2500 page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including PRESTONE AF3100 (Coolant / Antifreeze) and GMB 1204400 (Water Pump). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2021 Sprinter 2500 engines | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2021 Sprinter 2500 engines | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE Popular Fits: all 2021 Sprinter 2500 engines | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
| PEAK Fits: all 2021 Sprinter 2500 engines | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK Fits: all 2021 Sprinter 2500 engines | FXA1GAL | 🇺🇸 US 🇨🇦 CA | Final Charge Global1 Gallon | View on Amazon |
| PRESTONE Fits: all 2021 Sprinter 2500 engines | AFC12100 | 🇺🇸 US 🇨🇦 CA | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2021 Sprinter 2500 engines | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK Fits: all 2021 Sprinter 2500 engines | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK Fits: all 2021 Sprinter 2500 engines | PXA1GAL | 🇺🇸 US 🇨🇦 CA | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE Fits: all 2021 Sprinter 2500 engines | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| VALVOLINE Popular Fits: all 2021 Sprinter 2500 engines | 861399 | 🇺🇸 US 🇨🇦 CA | G40 Pink1 Gallon | View on Amazon |
| PEAK Fits: all 2021 Sprinter 2500 engines | PEV1GAL | 🇺🇸 US 🇨🇦 CA | OET European Extended Life Violet1 Gallon | View on Amazon |
| PENTOSIN Fits: all 2021 Sprinter 2500 engines | 8114306 | 🇺🇸 US 🇨🇦 CA | Pentofrost E1 Gallon | View on Amazon |
| PENTOSIN Fits: all 2021 Sprinter 2500 engines | 8113106 | 🇺🇸 US 🇨🇦 CA | Pentofrost E1.5 Liters | View on Amazon |
| PENTOSIN Fits: all 2021 Sprinter 2500 engines | 8113206 | 🇺🇸 US 🇨🇦 CA | Pentofrost E5 Liters | View on Amazon |
| VALVOLINE Fits: 2.1L L4 DIESEL Turbocharged, 3.0L V6 DIESEL Turbocharged | 877981 | 🇺🇸 US 🇨🇦 CA | G30 Purple1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
16 Coolant / Antifreeze parts for the 2021 Freightliner Sprinter 2500 come from 4 brands — PRESTONE, PEAK, VALVOLINE and 1 other brand. The "Popular" part is PRESTONE AF3100. 15 parts fit every engine; the other 1 is engine-specific.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 3 options from PRESTONE, VALVOLINE and PEAK — the catalog's value-priced group. PRESTONE AF3100 is listed in this group.
In the Heavy Duty grade, PEAK and PRESTONE supply 2 parts: rated for severe service. A representative part number is PEAK FXA1GAL.
In the Premium grade, PRESTONE and PEAK supply 4 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, PENTOSIN, VALVOLINE and PEAK supply 6 parts: built to original-equipment specification. A representative part number is VALVOLINE 861399.
Coolant Hose / Pipe
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN Fits: 2.1L L4 DIESEL Turbocharged | CHE0975 | 🇺🇸 US 🇨🇦 CA | Water Outlet To Thermostat Housing | View on Amazon |
| REIN Fits: 2.1L L4 DIESEL Turbocharged | CHE0891 | 🇺🇸 US 🇨🇦 CA | Oil Cooler To Pipe | View on Amazon |
| REIN Fits: 2.1L L4 DIESEL Turbocharged | CHE0889 | 🇺🇸 US 🇨🇦 CA | EGR Cooler To Valve | View on Amazon |
This table covers the hard pipes and extra hoses in the coolant circuit.
3 Coolant Hose / Pipe parts for the 2021 Freightliner Sprinter 2500 come from REIN.
This group includes REIN CHE0975, REIN CHE0891 and REIN CHE0889.
Coolant Hose / Pipe Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | 284350 | 🇺🇸 US 🇨🇦 CA | Inner Diameter [MM]: 9,5 | View on Amazon |
| ELRING Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | 738760 | 🇺🇸 US 🇨🇦 CA | Pipe At EGR ValveCoolant Pipe | View on Amazon |
This table covers the seals at the Coolant Hose / Pipe. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
ELRING supplies both parts for the 2021 Freightliner Sprinter 2500.
Listed part numbers: ELRING 284350 and ELRING 738760.
Coolant Hose Connector / Flange Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING Fits: 3.0L V6 DIESEL Turbocharged | 540890 | 🇺🇸 US 🇨🇦 CA | CrankcaseInlet Flange Seal | View on Amazon |
This table covers the seals at the Coolant Hose Connector / Flange. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
One part is listed for the 2021 Freightliner Sprinter 2500 — ELRING 540890.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | CPE0029P | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
One part is listed for the 2021 Freightliner Sprinter 2500 — REIN CPE0029P.
Intercooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | 2711574 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the intercoolers that cool turbo or supercharger charge air.
This group shows a single part: GPD 2711574.
Intercooler Air Hose / Pipe
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN Fits: 3.0L V6 DIESEL Turbocharged | TCH0330 | 🇺🇸 US 🇨🇦 CA | Left | View on Amazon |
This table covers the Intercooler Air Hose pipes.
This group shows a single part: REIN TCH0330.
Radiator Fan Clutch
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FOUR SEASONS Fits: 3.0L V6 DIESEL Turbocharged | 46104 | 🇺🇸 US 🇨🇦 CA | Electronic | View on Amazon |
| HAYDEN Fits: 3.0L V6 DIESEL Turbocharged | 8302 | 🇺🇸 US 🇨🇦 CA | Electronic | View on Amazon |
This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.
2 Radiator Fan Clutch parts for the 2021 Freightliner Sprinter 2500 come from 2 brands — FOUR SEASONS and HAYDEN.
Part numbers include FOUR SEASONS 46104 and HAYDEN 8302.
Radiator Hose
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DAYCO Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | 72838 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| DAYCO Fits: 2.0L L4 Turbocharged, 3.0L V6 DIESEL Turbocharged | 72814 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| REIN Fits: 3.0L V6 DIESEL Turbocharged | CHR0713 | 🇺🇸 US 🇨🇦 CA | Upper | View on Amazon |
| REIN Fits: 3.0L V6 DIESEL Turbocharged | CHR0664 | 🇺🇸 US 🇨🇦 CA | Lowerwithout Roof AC | View on Amazon |
This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.
4 Radiator Hose parts are listed for the 2021 Freightliner Sprinter 2500, from DAYCO and REIN.
Listed part numbers: DAYCO 72838, DAYCO 72814 and REIN CHR0713, plus the other parts above.
Thermostat
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 3.0L V6 DIESEL Turbocharged | 9025850 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: 3.0L V6 DIESEL Turbocharged | 623189 | 🇺🇸 US 🇨🇦 CA | Includes Housing, Seal | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
2 Thermostat parts are listed for the 2021 Freightliner Sprinter 2500, from DORMAN and MOTORAD.
Economy: 1 part, from DORMAN. A representative part number is DORMAN 9025850.
The Standard Replacement section: 1 option from MOTORAD. MOTORAD 623189 is listed in this group.
This group includes DORMAN 9025850 and MOTORAD 623189.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN Fits: 3.0L V6 DIESEL Turbocharged | WPA0531 | 🇺🇸 US 🇨🇦 CA | Auxiliary | View on Amazon |
| SKP Fits: 3.0L V6 DIESEL Turbocharged | SK1473080 | 🇺🇸 US 🇨🇦 CA | without Mounting Bracket | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GMB Popular Fits: 3.0L V6 DIESEL Turbocharged | 1204400 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DAYCO Fits: 3.0L V6 DIESEL Turbocharged | DP354 | 🇺🇸 US 🇨🇦 CA | Serpentine Belt Driven | View on Amazon |
| FVP Fits: 3.0L V6 DIESEL Turbocharged | 1204400 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FVP Fits: 3.0L V6 DIESEL Turbocharged | 1473080 | 🇺🇸 US 🇨🇦 CA | without Mounting BracketAuxiliary | View on Amazon |
| GMB Fits: 3.0L V6 DIESEL Turbocharged | 1472410 | 🇺🇸 US 🇨🇦 CA | Mounting Hardware Included: No | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
7 Water Pump parts are listed for the 2021 Freightliner Sprinter 2500, from GMB, FVP, REIN and 2 other brands. GMB 1204400 carries the "Popular" badge.
Economy: 2 parts, from REIN and SKP. A representative part number is REIN WPA0531.
The Standard Replacement section: 5 options from GMB, FVP and DAYCO. GMB 1204400 is listed in this group.
Listed part numbers: GMB 1204400, REIN WPA0531 and SKP SK1473080, plus the other parts above.
Water Pump Gasket
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING Fits: 3.0L V6 DIESEL Turbocharged | 540880 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.
This group shows a single part: ELRING 540880.
Buying Cooling System Parts for a 2021 Freightliner Sprinter 2500
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2021 Freightliner Sprinter 2500?
Our catalog currently lists 41 cooling system parts for the 2021 Freightliner Sprinter 2500 across 12 subcategories and 15 brands, covering all 3 engine options (2.0L L4 Turbocharged, 2.1L L4 DIESEL Turbocharged and 3.0L V6 DIESEL Turbocharged). Each part is matched to the engine(s) it fits.
Do cooling system parts differ between 2021 Freightliner Sprinter 2500 engines?
Some do. 15 parts fit every engine; the other 26 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.
What are the signs of cooling system problems on a 2021 Freightliner Sprinter 2500?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Freightliner Sprinter 2500 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2021 Freightliner Sprinter 2500?
First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2021 Freightliner Sprinter 2500
Cooling System Parts for Other Freightliner Sprinter 2500 Years
Switch vehicle or jump to a subcategory
Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.