2001 Isuzu NPR Cooling System Parts

Engine:

Showing parts for every engine. Select an engine to see only what fits.

The 2001 Isuzu NPR has 114 cooling system parts with verified fitment on this page — 17 part types and 29 brands, covering both the 4.8L L4 DIESEL Turbocharged and the 5.7L V8. Each part includes a manufacturer part number and application notes.

On the 2001 Isuzu NPR, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Thermostat (27 parts), Radiator Hose (16 parts) and Coolant / Antifreeze (14 parts). The other 14 part types cover the remaining 57 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE Fits: all 2001 NPR engines AF3055
🇺🇸 US 🇨🇦 CA
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
Fits:
NPR-HD
or:
NPR Base ModelExcept Class 8 Applications
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Economy

Brand Part Number Markets Notes Buy
FVP Popular Fits: all 2001 NPR engines MV5050GAL
🇺🇸 US 🇨🇦 CA
Extended LifeAll Makes / All Models
Fitment notes — FVP MV5050GAL
Extended LifeAll Makes / All Models1 Gallon
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PEAK Fits: all 2001 NPR engines BQA1GAL
🇺🇸 US 🇨🇦 CA
Blue Mountain Long LifeAll Vehicle
Fitment notes — PEAK BQA1GAL
Blue Mountain Long LifeAll Vehicle1 Gallon
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PRESTONE Fits: all 2001 NPR engines AF3100
🇺🇸 US 🇨🇦 CA
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
Fits:
NPR-HD
or:
NPR Base ModelExcept Class 8 Applications
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VALVOLINE Fits: all 2001 NPR engines 719009
🇺🇸 US 🇨🇦 CA
Multi-Vehicle Yellow1 Gallon
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Heavy Duty

Brand Part Number Markets Notes Buy
PEAK Fits: all 2001 NPR engines FXA1GAL
🇺🇸 US 🇨🇦 CA
Final Charge Global1 Gallon
Fitment notes — PEAK FXA1GAL
Final Charge Global1 GallonFINAL CHARGENITRITE FREEGLOBAL EXTENDED LIFE 1 GALLON
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PRESTONE Fits: all 2001 NPR engines AFC13000
🇺🇸 US 🇨🇦 CA
Command COR-Guard Nitrite Free-Noat Extended Life CoolantRed
Fitment notes — PRESTONE AFC13000
Command COR-Guard Nitrite Free-Noat Extended Life CoolantRed1 Galloncon
NPR Base ModelClass 7 Applications
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PRESTONE Fits: all 2001 NPR engines AFC12100
🇺🇸 US 🇨🇦 CA
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT
Fitment notes — PRESTONE AFC12100
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT1 GAL Ready To Use 50/50
Heavy Duty & Mixed Fleet Nitrite Free Extended Life CoolantYellow Fluid Class 1 - 8
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular Fits: all 2001 NPR engines AF2100
🇺🇸 US 🇨🇦 CA
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
Fits:
NPR-HD
or:
NPR Base ModelExcept Class 8 Applications
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PEAK Fits: all 2001 NPR engines PKP1GAL
🇺🇸 US 🇨🇦 CA
All Vehicles Antifreeze1 Gallon
Fitment notes — PEAK PKP1GAL
All Vehicles Antifreeze1 GallonPREMIUM1 GALLON10X MORE SCALE FIGHTING INHIBITORS10 YEAR/300K MILES
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PEAK Fits: all 2001 NPR engines PXA1GAL
🇺🇸 US 🇨🇦 CA
1 GallonGlobal Lifetime
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PRESTONE Fits: all 2001 NPR engines AFMAX
🇺🇸 US 🇨🇦 CA
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
Fits:
NPR-HD
or:
NPR Base ModelExcept Class 8 Applications
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Standard Replacement

Brand Part Number Markets Notes Buy
VALVOLINE Popular Fits: all 2001 NPR engines ZXEL1
🇺🇸 US 🇨🇦 CA
Dex-Cool Orange1 Gallon
Fitment notes — VALVOLINE ZXEL1
Dex-Cool Orange1 GallonOAT
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VALVOLINE Fits: all 2001 NPR engines 675130
🇺🇸 US 🇨🇦 CA
Asian Vehicle Red1 Gallon
Fitment notes — VALVOLINE 675130
Asian Vehicle Red1 GallonPOAT
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Reservoir

Brand Part Number Markets Notes Buy
DORMAN Fits: all 2001 NPR engines 6035603
🇺🇸 US 🇨🇦 CA
Fits NPR Base Modelor NPR-HDSingle Cab
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This table covers the overflow / expansion tanks that hold extra coolant.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
DORMAN Fits: all 2001 NPR engines 9241059
🇺🇸 US 🇨🇦 CA
NPR Base Model
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Cooling System Tester Adapter

Brand Part Number Markets Notes Buy
GATES Fits: all 2001 NPR engines 31428
🇺🇸 US 🇨🇦 CA
May Require Spacer Number 31416
Fitment notes — GATES 31428
May Require Spacer Number 31416
Cooling System Pressure
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MOTORAD Fits: all 2001 NPR engines 3121
🇺🇸 US 🇨🇦 CA
StandardRadiator Cap Adapter
Fitment notes — MOTORAD 3121
StandardRadiator Cap Adapter
Cooling System PressureRadiator Cap Adapter
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MOTORAD Fits: all 2001 NPR engines 3122
🇺🇸 US 🇨🇦 CA
Standard
Fitment notes — MOTORAD 3122
Standard
Cooling System Pressure
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STANT Fits: all 2001 NPR engines 12021
🇺🇸 US 🇨🇦 CA
Radiator Cap/Cooling System Tester Adapter
Fitment notes — STANT 12021
Radiator Cap/Cooling System Tester Adapter
Cooling System PressureRadiator Cap Adapter
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This table covers the adapters used to pressure-test this cooling system.

Intercooler

Brand Part Number Markets Notes Buy
CSF Fits: 4.8L L4 DIESEL Turbocharged 6051
🇺🇸 US 🇨🇦 CA
Tube & Fin
Fitment notes — CSF 6051
Tube & Fin
with Aluminum Tanks
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GPD Fits: 4.8L L4 DIESEL Turbocharged 2711272
🇺🇸 US 🇨🇦 CA
with 2.5 IN Inletwith 2.5 IN Outlets
Fitment notes — GPD 2711272
with 2.5 IN Inletwith 2.5 IN Outletswith 19.75 IN X 14.5 IN X 2In Core
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SPECTRA PREMIUM Fits: 4.8L L4 DIESEL Turbocharged 44010703
🇺🇸 US 🇨🇦 CA
with 19.75 IN X 14.5 IN X 2In Corewith 2.5 IN Inlet
Fitment notes — SPECTRA PREMIUM 44010703
with 19.75 IN X 14.5 IN X 2In Corewith 2.5 IN Inletwith 2.5 IN Outlets
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This table covers the intercoolers that cool turbo or supercharger charge air.

Radiator

Economy

Brand Part Number Markets Notes Buy
GPD Fits: 4.8L L4 DIESEL Turbocharged 9243220
🇺🇸 US 🇨🇦 CA
HD
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GPD Fits: 5.7L V8 9243242
🇺🇸 US 🇨🇦 CA
with Aluminum Core
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GPD Fits: 5.7L V8 9243243
🇺🇸 US 🇨🇦 CA
All MetalHeavy Duty
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GPD Fits: 5.7L V8 9282730
🇺🇸 US 🇨🇦 CA
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ULTRA-POWER Fits: 4.8L L4 DIESEL Turbocharged 20010701
🇺🇸 US 🇨🇦 CA
Fits 2WD160HP
Fitment notes — ULTRA-POWER 20010701
Fits:
2WD160HP
or:
23-1/4" X 21-1/4" X 1-7/16" CoreInlet 1-1/2"Outlet 1-1/2"with Raised Filler Neckwith Transmission Oil Cooler 15" Grille SideRadiator Cap is REQ
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Heavy Duty (All Metal Construction)

Brand Part Number Markets Notes Buy
CSF Popular Fits: 5.7L V8 3243
🇺🇸 US 🇨🇦 CA
3 RowAll Metal Multi Fit Model (Not Direct OE Match) with heater pipe & sensor port On Top tank
Fitment notes — CSF 3243
3 RowAll Metal Multi Fit Model (Not Direct OE Match) with heater pipe & sensor port On Top tankCopper Core / Brass Tank
with Heavy Duty Cooling
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Standard Replacement

Brand Part Number Markets Notes Buy
CSF Popular Fits: 4.8L L4 DIESEL Turbocharged 3210
🇺🇸 US 🇨🇦 CA
1 RowPlastic Tank / Aluminum Core
Fitment notes — CSF 3210
1 RowPlastic Tank / Aluminum Corewith Sensor Port On Top Tank.
OE # 5-87410-784-0, 8-97213-664-1, 8-97354-362-1, 8-97354-365-0, 8-97730-088-0, 97213664, 97354362, 97354365, 97730088
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CSF Popular Fits: 5.7L V8 3242
🇺🇸 US 🇨🇦 CA
1 RowPlastic Tank / Aluminum Core
Fitment notes — CSF 3242
1 RowPlastic Tank / Aluminum CoreMulti Fit Model (Not Direct OE Match) with Sensor Port On Top tank
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OSC Fits: 4.8L L4 DIESEL Turbocharged HD9126
🇺🇸 US 🇨🇦 CA
NPR Base Model23-1/4" Tall
Fitment notes — OSC HD9126
NPR Base Model23-1/4" TallOutlet On Bottom Driver Side
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OSC Fits: 5.7L V8 HD1176
🇺🇸 US 🇨🇦 CA
Fits NPR-HD
Fitment notes — OSC HD1176
Fits:
NPR-HD
or:
NPR Base Model23-1/4" TallOutlet On Bottom Passenger Side
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SPECTRA PREMIUM Fits: 4.8L L4 DIESEL Turbocharged 20010701
🇺🇸 US 🇨🇦 CA
NPR Base Modelwith 23.25 IN X 21.25 IN X 1.4375 IN Core
Fitment notes — SPECTRA PREMIUM 20010701
NPR Base Modelwith 23.25 IN X 21.25 IN X 1.4375 IN Core1.5 IN Inlet and Outletwith Transmission Oil Cooler 15" Grille Sidewith Raised Filler Neck
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Locking Replacement

Brand Part Number Markets Notes Buy
CALORSTAT Fits: all 2001 NPR engines RC0212
🇺🇸 US 🇨🇦 CA
PerformanceIncludes 2 seals
Fitment notes — CALORSTAT RC0212
PerformanceIncludes 2 sealsLever OpeningMetallic
with A 44 mm (1.73") DiameterPSI - 20.0
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GATES Fits: all 2001 NPR engines 31534
🇺🇸 US 🇨🇦 CA
Safety Release Radiator Cap
Fitment notes — GATES 31534
Safety Release Radiator Cap
Check hood clearance prior to installing this cap
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MOTORAD Fits: all 2001 NPR engines ST16R
🇺🇸 US 🇨🇦 CA
Safety LeverIndicator Markings Color: Blue, Red
Fitment notes — MOTORAD ST16R
Safety LeverIndicator Markings Color: Blue, Red
Relief Pressure 16 lbs
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Standard Replacement

Brand Part Number Markets Notes Buy
MOTORAD Popular Fits: all 2001 NPR engines T16R
🇺🇸 US 🇨🇦 CA
StandardIndicator Markings Color: Silver
Fitment notes — MOTORAD T16R
StandardIndicator Markings Color: Silver
Relief Pressure 16 lbs
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SKP Popular Fits: all 2001 NPR engines SK10233
🇺🇸 US 🇨🇦 CA
Pressure Rating 16 psi
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CSF Fits: 5.7L V8 4503
🇺🇸 US 🇨🇦 CA
Mini, 16 PSI
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GATES Fits: all 2001 NPR engines 31336
🇺🇸 US 🇨🇦 CA
OE Type
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Blade

Brand Part Number Markets Notes Buy
DORMAN Fits: 4.8L L4 DIESEL Turbocharged 6205603
🇺🇸 US 🇨🇦 CA
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This table covers the Radiator Fan blades. Typical signs include chatter, streaks, or a skip at the top of the stroke. Confirm left and right lengths in the notes — they are often different.

Radiator Fan Clutch

Brand Part Number Markets Notes Buy
FOUR SEASONS Fits: 5.7L V8 36947
🇺🇸 US 🇨🇦 CA
Severe Duty Thermal
Fitment notes — FOUR SEASONS 36947
Severe Duty Thermal
Standard Rotation
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HAYDEN Fits: 5.7L V8 2787
🇺🇸 US 🇨🇦 CA
ThermalSevere Duty
Fitment notes — HAYDEN 2787
ThermalSevere Duty
Standard Rotation
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NISSENS Fits: 5.7L V8 86465
🇺🇸 US 🇨🇦 CA
Severe Duty Thermal
Fitment notes — NISSENS 86465
Severe Duty Thermal
Standard Rotation
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SKP Fits: 5.7L V8 SK36947
🇺🇸 US 🇨🇦 CA
Thermal
Fitment notes — SKP SK36947
Thermal
Fits:
NPR Base ModelAssemblywith Reverse Rotationor NPR-HDwith Reverse RotationAssembly
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This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.

Radiator Hose

Brand Part Number Markets Notes Buy
CONTINENTAL Popular Fits: 4.8L L4 DIESEL Turbocharged 62699
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — CONTINENTAL 62699
Molded
Lower
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CONTINENTAL Popular Fits: 5.7L V8 60773
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — CONTINENTAL 60773
Molded
UPPERCUT TO FIT
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GATES Popular Fits: 4.8L L4 DIESEL Turbocharged 23096
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 23096
Molded
UpperEngine To Radiator
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GATES Popular Fits: 5.7L V8 22731
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 22731
Molded
UpperEngine To Radiator
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ACDELCO Fits: 4.8L L4 DIESEL Turbocharged 20456S
🇺🇸 US 🇨🇦 CA
Professional / GoldMolded
Fitment notes — ACDELCO 20456S
Professional / GoldMolded
UpperEngine To Radiator
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ACDELCO Fits: 4.8L L4 DIESEL Turbocharged 24564L
🇺🇸 US 🇨🇦 CA
Professional / GoldMolded
Fitment notes — ACDELCO 24564L
Professional / GoldMolded
LowerEngine To Radiator
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ACDELCO Fits: 5.7L V8 24484L
🇺🇸 US 🇨🇦 CA
Professional / GoldMolded
Fitment notes — ACDELCO 24484L
Professional / GoldMolded
LowerEngine To Radiator
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CONTINENTAL Fits: 4.8L L4 DIESEL Turbocharged 62807
🇺🇸 US 🇨🇦 CA
MoldedEnd 2 Hose Inside Diameter: 1.62 In
Fitment notes — CONTINENTAL 62807
MoldedEnd 2 Hose Inside Diameter: 1.62 In
Upper
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CONTINENTAL Fits: 5.7L V8 61181
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — CONTINENTAL 61181
Molded
Lower
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DAYCO Fits: 4.8L L4 DIESEL Turbocharged 72040
🇺🇸 US 🇨🇦 CA
Curved
Fitment notes — DAYCO 72040
Curved
Upper
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DAYCO Fits: 4.8L L4 DIESEL Turbocharged 72041
🇺🇸 US 🇨🇦 CA
Curved
Fitment notes — DAYCO 72041
Curved
Lower
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DAYCO Fits: 5.7L V8 E72036
🇺🇸 US 🇨🇦 CA
Upper Radiator or Coolant HoseCurved
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DAYCO Fits: 5.7L V8 72036
🇺🇸 US 🇨🇦 CA
Curved
Fitment notes — DAYCO 72036
Curved
Upper
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DAYCO Fits: 5.7L V8 72037
🇺🇸 US 🇨🇦 CA
Curved
Fitment notes — DAYCO 72037
Curved
Lower
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GATES Fits: 4.8L L4 DIESEL Turbocharged 23095
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 23095
Molded
LowerEngine To Radiator
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GATES Fits: 5.7L V8 22732
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 22732
Molded
LowerEngine To Radiator
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This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
NTK Popular Fits: all 2001 NPR engines EF0008
🇺🇸 US 🇨🇦 CA
Sensor OnlyOval Connector
Fitment notes — NTK EF0008
Sensor OnlyOval Connector
NPR Base ModelLocated in Intake Manifold
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GPD Fits: all 2001 NPR engines 1711697
🇺🇸 US 🇨🇦 CA
with Oval Connectorwith 2 Terminal(s)
Fitment notes — GPD 1711697
with Oval Connectorwith 2 Terminal(s)with 3/8 in-18 Threads
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STANDARD MOTOR PRODUCTS Fits: all 2001 NPR engines TS375T
🇺🇸 US 🇨🇦 CA
T-Series14" OAL
Fitment notes — STANDARD MOTOR PRODUCTS TS375T
T-Series14" OAL
NPR Base Modelwith Gauge
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ULTRA-POWER Fits: all 2001 NPR engines 5S1018
🇺🇸 US 🇨🇦 CA
INTAKE MANIFOLD
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Standard Replacement

Brand Part Number Markets Notes Buy
WELLS Popular Fits: all 2001 NPR engines 5S1018
🇺🇸 US 🇨🇦 CA
Connector Shape: Oval
Fitment notes — WELLS 5S1018
Connector Shape: Oval
NPR Base ModelLocated in Intake Manifold
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ROSTRA Fits: 5.7L V8 680011
🇺🇸 US 🇨🇦 CA
Sender
Fitment notes — ROSTRA 680011
Sender
NPR Base Modelwith Gauge
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STANDARD MOTOR PRODUCTS Fits: all 2001 NPR engines TS375
🇺🇸 US 🇨🇦 CA
14" OAL
Fitment notes — STANDARD MOTOR PRODUCTS TS375
14" OAL
NPR Base Modelwith Gauge
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WELLS Fits: 5.7L V8 1T1064
🇺🇸 US 🇨🇦 CA
Terminal Quantity: 1
Fitment notes — WELLS 1T1064
Terminal Quantity: 1
NPR Base Modelwith Gauge
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Thermostat

Heavy Duty

Brand Part Number Markets Notes Buy
MOTORAD Popular Fits: 5.7L V8 5265195
🇺🇸 US 🇨🇦 CA
Ultra StatIncludes seal
Fitment notes — MOTORAD 5265195
Ultra StatIncludes seal
195 Degrees FOE Specified Temperature
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GATES Fits: 4.8L L4 DIESEL Turbocharged 33964
🇺🇸 US 🇨🇦 CA
Heavy-Duty
Fitment notes — GATES 33964
Heavy-Duty
Driver Side188 DegreeSeal Included
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GATES Fits: 4.8L L4 DIESEL Turbocharged 33965
🇺🇸 US 🇨🇦 CA
Heavy-Duty
Fitment notes — GATES 33965
Heavy-Duty
Passenger Side185 DegreeSeal Included
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GATES Fits: 5.7L V8 33019S
🇺🇸 US 🇨🇦 CA
Premium
Fitment notes — GATES 33019S
Premium
195 DegreeAlternate TemperatureSeal Included
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MOTORAD Fits: 5.7L V8 5169KTUS
🇺🇸 US 🇨🇦 CA
Includes housing, Ultra Stat thermostat and sealKit
Fitment notes — MOTORAD 5169KTUS
Includes housing, Ultra Stat thermostat and sealKitUltra Stat
195 Degrees FOE Specified Temperature
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Performance

Brand Part Number Markets Notes Buy
MOTORAD Popular Fits: 5.7L V8 2065195
🇺🇸 US 🇨🇦 CA
High FlowIncludes seal
Fitment notes — MOTORAD 2065195
High FlowIncludes seal
195 Degrees FOE Specified Temperature
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MOTORAD Popular Fits: 5.7L V8 2065180
🇺🇸 US 🇨🇦 CA
High FlowIncludes seal
Fitment notes — MOTORAD 2065180
High FlowIncludes seal
180 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 2065160
🇺🇸 US 🇨🇦 CA
High FlowIncludes seal
Fitment notes — MOTORAD 2065160
High FlowIncludes seal
160 Degrees FAlternate Temperature Option
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Premium

Brand Part Number Markets Notes Buy
MOTORAD Popular Fits: 5.7L V8 7228180
🇺🇸 US 🇨🇦 CA
Fail-SafeIncludes seal
Fitment notes — MOTORAD 7228180
Fail-SafeIncludes seal
180 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 7228160
🇺🇸 US 🇨🇦 CA
Fail-SafeIncludes seal
Fitment notes — MOTORAD 7228160
Fail-SafeIncludes seal
160 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 7228195
🇺🇸 US 🇨🇦 CA
Fail-SafeIncludes seal
Fitment notes — MOTORAD 7228195
Fail-SafeIncludes seal
195 Degrees FOE Specified Temperature
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MOTORAD Fits: 5.7L V8 7228170
🇺🇸 US 🇨🇦 CA
Fail-SafeIncludes seal
Fitment notes — MOTORAD 7228170
Fail-SafeIncludes seal
170 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 5169KTFS
🇺🇸 US 🇨🇦 CA
Fail-SafeIncludes Housing, and Seal
Fitment notes — MOTORAD 5169KTFS
Fail-SafeIncludes Housing, and SealKit
195 Degrees FOE Specified Temperature
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Standard Replacement

Brand Part Number Markets Notes Buy
MOTORAD Popular Fits: 4.8L L4 DIESEL Turbocharged 405785
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 405785
Includes Seal
Passenger Side185 Degrees F
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MOTORAD Popular Fits: 4.8L L4 DIESEL Turbocharged 405680
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 405680
Includes Seal
Driver Side180 Degrees FOE Specified Temperature
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MOTORAD Popular Fits: 5.7L V8 265180
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 265180
Includes Seal
180 Degrees FAlternate Temperature Option
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CALORSTAT Fits: all 2001 NPR engines TH153882
🇺🇸 US 🇨🇦 CA
PerformanceDoes Not Include Seal
Fitment notes — CALORSTAT TH153882
PerformanceDoes Not Include Seal
180.0 F Degrees
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CALORSTAT Fits: all 2001 NPR engines THF153882
🇺🇸 US 🇨🇦 CA
High EfficiencyLarger Main Valve Seat
Fitment notes — CALORSTAT THF153882
High EfficiencyLarger Main Valve SeatDoes Not Include Seal
180.0 Degrees
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CALORSTAT Fits: all 2001 NPR engines TH153871
🇺🇸 US 🇨🇦 CA
PerformanceDoes Not Include Seal
Fitment notes — CALORSTAT TH153871
PerformanceDoes Not Include Seal
160.0 Degrees
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CALORSTAT Fits: all 2001 NPR engines THF598191J
🇺🇸 US 🇨🇦 CA
High EfficiencyLarger Main Valve Seat
Fitment notes — CALORSTAT THF598191J
High EfficiencyLarger Main Valve SeatIncludes 1 Rubber Gasket
196.0 Degrees
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CALORSTAT Fits: all 2001 NPR engines TH153891
🇺🇸 US 🇨🇦 CA
PerformanceDoes Not Include Seal
Fitment notes — CALORSTAT TH153891
PerformanceDoes Not Include Seal
196.0 F Degrees
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GATES Fits: 5.7L V8 34769
🇺🇸 US 🇨🇦 CA
OE Exact
Fitment notes — GATES 34769
OE Exact
198 DegreeOE TemperatureSeal Included
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MAHLE / CLEVITE Fits: 5.7L V8 TX5292
🇺🇸 US 🇨🇦 CA
Includes Gasket or Seal
Fitment notes — MAHLE / CLEVITE TX5292
Includes Gasket or Seal
Start to Open Temperature: 92 C
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MOTORAD Fits: 5.7L V8 265195
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 265195
Includes Seal
195 Degrees FOE Specified Temperature
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MOTORAD Fits: 5.7L V8 265170
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 265170
Includes Seal
170 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 265160
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD 265160
Includes Seal
160 Degrees FAlternate Temperature Option
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MOTORAD Fits: 5.7L V8 5169KT
🇺🇸 US 🇨🇦 CA
Includes Housing, Thermostat and SealKit
Fitment notes — MOTORAD 5169KT
Includes Housing, Thermostat and SealKit
195 Degrees FOE Specified Temperature
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This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.

Thermostat / Thermostat Housing / Water Outlet Seal

Brand Part Number Markets Notes Buy
MAHLE / CLEVITE Fits: 5.7L V8 C31273
🇺🇸 US 🇨🇦 CA
Molded Rubber
Fitment notes — MAHLE / CLEVITE C31273
Molded Rubber
Thermostat Seal
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This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Thermostat Housing / Water Outlet

Economy

Brand Part Number Markets Notes Buy
DORMAN Fits: 5.7L V8 902754
🇺🇸 US 🇨🇦 CA
Thermostat Housing
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Standard Replacement

Brand Part Number Markets Notes Buy
MOTORAD Fits: 5.7L V8 CH5169
🇺🇸 US 🇨🇦 CA
Includes Gasket
Fitment notes — MOTORAD CH5169
Includes Gasket
Water Outlet
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This table covers the housings and outlets the thermostat sits in.

Water Pump

Economy

Brand Part Number Markets Notes Buy
FVP Fits: 5.7L V8 US5077
🇺🇸 US 🇨🇦 CA
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SKP Fits: 5.7L V8 SK1301820
🇺🇸 US 🇨🇦 CA
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US MOTOR WORKS Fits: 5.7L V8 US5077
🇺🇸 US 🇨🇦 CA
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WJB / INMOTION PARTS Fits: 5.7L V8 WU5077
🇺🇸 US 🇨🇦 CA
From 10/1995
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High Volume / Pressure

Brand Part Number Markets Notes Buy
FVP Fits: 5.7L V8 US5077H
🇺🇸 US 🇨🇦 CA
High Performance
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GMB Fits: 5.7L V8 1301820P
🇺🇸 US 🇨🇦 CA
High Performance
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US MOTOR WORKS Fits: 5.7L V8 US5077H
🇺🇸 US 🇨🇦 CA
High Performance
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Standard Replacement

Brand Part Number Markets Notes Buy
DAYCO Popular Fits: 5.7L V8 DP957
🇺🇸 US 🇨🇦 CA
Serpentine Belt DrivenStandard Duty
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GATES Popular Fits: 5.7L V8 43315
🇺🇸 US 🇨🇦 CA
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GMB Popular Fits: 5.7L V8 1301820
🇺🇸 US 🇨🇦 CA
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DAYCO Fits: 5.7L V8 DP957H
🇺🇸 US 🇨🇦 CA
Heavy Duty
Fitment notes — DAYCO DP957H
Heavy Duty
Serpentine Belt Driven
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This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.

Water Pump Gasket

Brand Part Number Markets Notes Buy
MAHLE / CLEVITE Fits: 5.7L V8 K25935
🇺🇸 US 🇨🇦 CA
Paper
Fitment notes — MAHLE / CLEVITE K25935
Paper
Water Pump To Block
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MAHLE / CLEVITE Fits: 5.7L V8 K27091
🇺🇸 US 🇨🇦 CA
Paper
Fitment notes — MAHLE / CLEVITE K27091
Paper
Water Pump to Plate
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This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Water Pump Stud Kit

Brand Part Number Markets Notes Buy
DORMAN Fits: 5.7L V8 902804
🇺🇸 US 🇨🇦 CA
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This table covers the Water Pump Stud kits.

Buying Cooling System Parts for a 2001 Isuzu NPR

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Thermostat and Radiator Hose .

Frequently Asked Questions

How many cooling system parts fit the 2001 Isuzu NPR?

Our catalog currently lists 114 cooling system parts for the 2001 Isuzu NPR across 17 subcategories and 29 brands, covering both the 4.8L L4 DIESEL Turbocharged and the 5.7L V8. Each part is matched to the engine(s) it fits.

Do cooling system parts differ between 2001 Isuzu NPR engines?

Some do. 37 parts fit every engine; the other 77 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.

What are the signs of cooling system problems on a 2001 Isuzu NPR?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2001 Isuzu NPR was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2001 Isuzu NPR?

First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2001 Isuzu NPR

Cooling System Parts for Other Isuzu NPR Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.