The 2001 Isuzu NPR has 114 cooling system parts with verified fitment on this page — 17 part types and 29 brands, covering both the 4.8L L4 DIESEL Turbocharged and the 5.7L V8. Each part includes a manufacturer part number and application notes.
On the 2001 Isuzu NPR, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Thermostat (27 parts), Radiator Hose (16 parts) and Coolant / Antifreeze (14 parts). The other 14 part types cover the remaining 57 parts.
The 2001 Isuzu NPR was sold with both the 4.8L L4 DIESEL Turbocharged and the 5.7L V8. 37 parts fit every engine; the other 77 are engine-specific. Each part shows which engine(s) it fits.
29 brands supply cooling system parts for the 2001 Isuzu NPR, led by MOTORAD (22 parts), GATES (12 parts) and DAYCO (7 parts), plus 26 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2001 Isuzu NPR. 24 parts have it, including FVP MV5050GAL (Coolant / Antifreeze) and CSF 3243 (Radiator). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2001 NPR engines | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Popular Fits: all 2001 NPR engines | MV5050GAL | 🇺🇸 US 🇨🇦 CA | Extended LifeAll Makes / All Models | View on Amazon |
| PEAK Fits: all 2001 NPR engines | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE Fits: all 2001 NPR engines | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE Fits: all 2001 NPR engines | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK Fits: all 2001 NPR engines | FXA1GAL | 🇺🇸 US 🇨🇦 CA | Final Charge Global1 Gallon | View on Amazon |
| PRESTONE Fits: all 2001 NPR engines | AFC13000 | 🇺🇸 US 🇨🇦 CA | Command COR-Guard Nitrite Free-Noat Extended Life CoolantRed | View on Amazon |
| PRESTONE Fits: all 2001 NPR engines | AFC12100 | 🇺🇸 US 🇨🇦 CA | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2001 NPR engines | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK Fits: all 2001 NPR engines | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK Fits: all 2001 NPR engines | PXA1GAL | 🇺🇸 US 🇨🇦 CA | 1 GallonGlobal Lifetime | View on Amazon |
| PRESTONE Fits: all 2001 NPR engines | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| VALVOLINE Popular Fits: all 2001 NPR engines | ZXEL1 | 🇺🇸 US 🇨🇦 CA | Dex-Cool Orange1 Gallon | View on Amazon |
| VALVOLINE Fits: all 2001 NPR engines | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
14 Coolant / Antifreeze parts are listed for the 2001 Isuzu NPR, from PRESTONE, PEAK, VALVOLINE and 1 other brand. FVP MV5050GAL carries the "Popular" badge. All of them fit every engine offered in the 2001 NPR.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, FVP, PEAK, PRESTONE and 1 other brand supply 4 parts: the catalog's value-priced group. A representative part number is FVP MV5050GAL.
The Heavy Duty section lists 3 options from PRESTONE and PEAK — rated for severe service. PEAK FXA1GAL is listed in this group.
The Premium section lists 4 options from PRESTONE and PEAK — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 2 options from VALVOLINE — built to original-equipment specification. VALVOLINE ZXEL1 is listed in this group.
Coolant Reservoir
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: all 2001 NPR engines | 6035603 | 🇺🇸 US 🇨🇦 CA | Fits NPR Base Modelor NPR-HDSingle Cab | View on Amazon |
This table covers the overflow / expansion tanks that hold extra coolant.
This group shows a single part: DORMAN 6035603.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: all 2001 NPR engines | 9241059 | 🇺🇸 US 🇨🇦 CA | NPR Base Model | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: DORMAN 9241059.
Cooling System Tester Adapter
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Fits: all 2001 NPR engines | 31428 | 🇺🇸 US 🇨🇦 CA | May Require Spacer Number 31416 | View on Amazon |
| MOTORAD Fits: all 2001 NPR engines | 3121 | 🇺🇸 US 🇨🇦 CA | StandardRadiator Cap Adapter | View on Amazon |
| MOTORAD Fits: all 2001 NPR engines | 3122 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
| STANT Fits: all 2001 NPR engines | 12021 | 🇺🇸 US 🇨🇦 CA | Radiator Cap/Cooling System Tester Adapter | View on Amazon |
This table covers the adapters used to pressure-test this cooling system.
4 Cooling System Tester Adapter parts are listed for the 2001 Isuzu NPR, from MOTORAD, GATES and STANT. All of them fit every engine offered in the 2001 NPR.
Part numbers include GATES 31428, MOTORAD 3121 and MOTORAD 3122, among others listed above.
Intercooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Fits: 4.8L L4 DIESEL Turbocharged | 6051 | 🇺🇸 US 🇨🇦 CA | Tube & Fin | View on Amazon |
| GPD Fits: 4.8L L4 DIESEL Turbocharged | 2711272 | 🇺🇸 US 🇨🇦 CA | with 2.5 IN Inletwith 2.5 IN Outlets | View on Amazon |
| SPECTRA PREMIUM Fits: 4.8L L4 DIESEL Turbocharged | 44010703 | 🇺🇸 US 🇨🇦 CA | with 19.75 IN X 14.5 IN X 2In Corewith 2.5 IN Inlet | View on Amazon |
This table covers the intercoolers that cool turbo or supercharger charge air.
3 Intercooler parts are listed for the 2001 Isuzu NPR, from CSF, GPD and SPECTRA PREMIUM.
This group includes CSF 6051, GPD 2711272 and SPECTRA PREMIUM 44010703.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD Fits: 4.8L L4 DIESEL Turbocharged | 9243220 | 🇺🇸 US 🇨🇦 CA | HD | View on Amazon |
| GPD Fits: 5.7L V8 | 9243242 | 🇺🇸 US 🇨🇦 CA | with Aluminum Core | View on Amazon |
| GPD Fits: 5.7L V8 | 9243243 | 🇺🇸 US 🇨🇦 CA | All MetalHeavy Duty | View on Amazon |
| GPD Fits: 5.7L V8 | 9282730 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| ULTRA-POWER Fits: 4.8L L4 DIESEL Turbocharged | 20010701 | 🇺🇸 US 🇨🇦 CA | Fits 2WD160HP | View on Amazon |
Heavy Duty (All Metal Construction)
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Popular Fits: 5.7L V8 | 3243 | 🇺🇸 US 🇨🇦 CA | 3 RowAll Metal Multi Fit Model (Not Direct OE Match) with heater pipe & sensor port On Top tank | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Popular Fits: 4.8L L4 DIESEL Turbocharged | 3210 | 🇺🇸 US 🇨🇦 CA | 1 RowPlastic Tank / Aluminum Core | View on Amazon |
| CSF Popular Fits: 5.7L V8 | 3242 | 🇺🇸 US 🇨🇦 CA | 1 RowPlastic Tank / Aluminum Core | View on Amazon |
| OSC Fits: 4.8L L4 DIESEL Turbocharged | HD9126 | 🇺🇸 US 🇨🇦 CA | NPR Base Model23-1/4" Tall | View on Amazon |
| OSC Fits: 5.7L V8 | HD1176 | 🇺🇸 US 🇨🇦 CA | Fits NPR-HD | View on Amazon |
| SPECTRA PREMIUM Fits: 4.8L L4 DIESEL Turbocharged | 20010701 | 🇺🇸 US 🇨🇦 CA | NPR Base Modelwith 23.25 IN X 21.25 IN X 1.4375 IN Core | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
11 Radiator parts are listed for the 2001 Isuzu NPR, from GPD, CSF, OSC and 2 other brands. CSF 3243 carries the "Popular" badge.
Economy: 5 parts, from GPD and ULTRA-POWER. A representative part number is GPD 9243220.
The Heavy Duty (All Metal Construction) section lists 1 option from CSF — rated for severe service. CSF 3243 is listed in this group.
The Standard Replacement section: 5 options from CSF, OSC and SPECTRA PREMIUM. CSF 3210 is listed in this group.
Radiator Cap
Locking Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT Fits: all 2001 NPR engines | RC0212 | 🇺🇸 US 🇨🇦 CA | PerformanceIncludes 2 seals | View on Amazon |
| GATES Fits: all 2001 NPR engines | 31534 | 🇺🇸 US 🇨🇦 CA | Safety Release Radiator Cap | View on Amazon |
| MOTORAD Fits: all 2001 NPR engines | ST16R | 🇺🇸 US 🇨🇦 CA | Safety LeverIndicator Markings Color: Blue, Red | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: all 2001 NPR engines | T16R | 🇺🇸 US 🇨🇦 CA | StandardIndicator Markings Color: Silver | View on Amazon |
| SKP Popular Fits: all 2001 NPR engines | SK10233 | 🇺🇸 US 🇨🇦 CA | Pressure Rating 16 psi | View on Amazon |
| CSF Fits: 5.7L V8 | 4503 | 🇺🇸 US 🇨🇦 CA | Mini, 16 PSI | View on Amazon |
| GATES Fits: all 2001 NPR engines | 31336 | 🇺🇸 US 🇨🇦 CA | OE Type | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
7 Radiator Cap parts are listed for the 2001 Isuzu NPR, from GATES, MOTORAD, CALORSTAT and 2 other brands. MOTORAD T16R carries the "Popular" badge. 6 parts fit every engine; the other 1 is engine-specific.
The Locking Replacement section lists 3 options from CALORSTAT, GATES and MOTORAD — grouped under the catalog's "Locking Replacement" designation — the notes column spells out what sets them apart. CALORSTAT RC0212 is listed in this group.
The Standard Replacement section: 4 options from MOTORAD, SKP, CSF and 1 other brand. MOTORAD T16R is listed in this group.
Listed part numbers: MOTORAD T16R, CALORSTAT RC0212 and GATES 31534, plus the other parts above.
Radiator Fan Blade
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 4.8L L4 DIESEL Turbocharged | 6205603 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the Radiator Fan blades. Typical signs include chatter, streaks, or a skip at the top of the stroke. Confirm left and right lengths in the notes — they are often different.
This group shows a single part: DORMAN 6205603.
Radiator Fan Clutch
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FOUR SEASONS Fits: 5.7L V8 | 36947 | 🇺🇸 US 🇨🇦 CA | Severe Duty Thermal | View on Amazon |
| HAYDEN Fits: 5.7L V8 | 2787 | 🇺🇸 US 🇨🇦 CA | ThermalSevere Duty | View on Amazon |
| NISSENS Fits: 5.7L V8 | 86465 | 🇺🇸 US 🇨🇦 CA | Severe Duty Thermal | View on Amazon |
| SKP Fits: 5.7L V8 | SK36947 | 🇺🇸 US 🇨🇦 CA | Thermal | View on Amazon |
This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.
4 Radiator Fan Clutch parts are listed for the 2001 Isuzu NPR, from FOUR SEASONS, HAYDEN, NISSENS and 1 other brand.
Listed part numbers: FOUR SEASONS 36947, HAYDEN 2787 and NISSENS 86465, plus the other parts above.
Radiator Hose
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CONTINENTAL Popular Fits: 4.8L L4 DIESEL Turbocharged | 62699 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| CONTINENTAL Popular Fits: 5.7L V8 | 60773 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES Popular Fits: 4.8L L4 DIESEL Turbocharged | 23096 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES Popular Fits: 5.7L V8 | 22731 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| ACDELCO Fits: 4.8L L4 DIESEL Turbocharged | 20456S | 🇺🇸 US 🇨🇦 CA | Professional / GoldMolded | View on Amazon |
| ACDELCO Fits: 4.8L L4 DIESEL Turbocharged | 24564L | 🇺🇸 US 🇨🇦 CA | Professional / GoldMolded | View on Amazon |
| ACDELCO Fits: 5.7L V8 | 24484L | 🇺🇸 US 🇨🇦 CA | Professional / GoldMolded | View on Amazon |
| CONTINENTAL Fits: 4.8L L4 DIESEL Turbocharged | 62807 | 🇺🇸 US 🇨🇦 CA | MoldedEnd 2 Hose Inside Diameter: 1.62 In | View on Amazon |
| CONTINENTAL Fits: 5.7L V8 | 61181 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| DAYCO Fits: 4.8L L4 DIESEL Turbocharged | 72040 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| DAYCO Fits: 4.8L L4 DIESEL Turbocharged | 72041 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| DAYCO Fits: 5.7L V8 | E72036 | 🇺🇸 US 🇨🇦 CA | Upper Radiator or Coolant HoseCurved | View on Amazon |
| DAYCO Fits: 5.7L V8 | 72036 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| DAYCO Fits: 5.7L V8 | 72037 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| GATES Fits: 4.8L L4 DIESEL Turbocharged | 23095 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES Fits: 5.7L V8 | 22732 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.
16 Radiator Hose parts for the 2001 Isuzu NPR come from 4 brands — DAYCO, CONTINENTAL, GATES and 1 other brand. The "Popular" part is CONTINENTAL 62699.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NTK Popular Fits: all 2001 NPR engines | EF0008 | 🇺🇸 US 🇨🇦 CA | Sensor OnlyOval Connector | View on Amazon |
| GPD Fits: all 2001 NPR engines | 1711697 | 🇺🇸 US 🇨🇦 CA | with Oval Connectorwith 2 Terminal(s) | View on Amazon |
| STANDARD MOTOR PRODUCTS Fits: all 2001 NPR engines | TS375T | 🇺🇸 US 🇨🇦 CA | T-Series14" OAL | View on Amazon |
| ULTRA-POWER Fits: all 2001 NPR engines | 5S1018 | 🇺🇸 US 🇨🇦 CA | INTAKE MANIFOLD | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| WELLS Popular Fits: all 2001 NPR engines | 5S1018 | 🇺🇸 US 🇨🇦 CA | Connector Shape: Oval | View on Amazon |
| ROSTRA Fits: 5.7L V8 | 680011 | 🇺🇸 US 🇨🇦 CA | Sender | View on Amazon |
| STANDARD MOTOR PRODUCTS Fits: all 2001 NPR engines | TS375 | 🇺🇸 US 🇨🇦 CA | 14" OAL | View on Amazon |
| WELLS Fits: 5.7L V8 | 1T1064 | 🇺🇸 US 🇨🇦 CA | Terminal Quantity: 1 | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
8 Temperature Sender / Sensor parts are listed for the 2001 Isuzu NPR, from STANDARD MOTOR PRODUCTS, WELLS, NTK and 3 other brands. NTK EF0008 carries the "Popular" badge. 6 parts fit every engine; the other 2 are engine-specific.
Economy: 4 parts, from NTK, GPD, STANDARD MOTOR PRODUCTS and 1 other brand. A representative part number is NTK EF0008.
The Standard Replacement section: 4 options from WELLS, ROSTRA and STANDARD MOTOR PRODUCTS. WELLS 5S1018 is listed in this group.
Part numbers include NTK EF0008, GPD 1711697 and STANDARD MOTOR PRODUCTS TS375T, among others listed above.
Thermostat
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: 5.7L V8 | 5265195 | 🇺🇸 US 🇨🇦 CA | Ultra StatIncludes seal | View on Amazon |
| GATES Fits: 4.8L L4 DIESEL Turbocharged | 33964 | 🇺🇸 US 🇨🇦 CA | Heavy-Duty | View on Amazon |
| GATES Fits: 4.8L L4 DIESEL Turbocharged | 33965 | 🇺🇸 US 🇨🇦 CA | Heavy-Duty | View on Amazon |
| GATES Fits: 5.7L V8 | 33019S | 🇺🇸 US 🇨🇦 CA | Premium | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 5169KTUS | 🇺🇸 US 🇨🇦 CA | Includes housing, Ultra Stat thermostat and sealKit | View on Amazon |
Performance
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: 5.7L V8 | 2065195 | 🇺🇸 US 🇨🇦 CA | High FlowIncludes seal | View on Amazon |
| MOTORAD Popular Fits: 5.7L V8 | 2065180 | 🇺🇸 US 🇨🇦 CA | High FlowIncludes seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 2065160 | 🇺🇸 US 🇨🇦 CA | High FlowIncludes seal | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: 5.7L V8 | 7228180 | 🇺🇸 US 🇨🇦 CA | Fail-SafeIncludes seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 7228160 | 🇺🇸 US 🇨🇦 CA | Fail-SafeIncludes seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 7228195 | 🇺🇸 US 🇨🇦 CA | Fail-SafeIncludes seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 7228170 | 🇺🇸 US 🇨🇦 CA | Fail-SafeIncludes seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 5169KTFS | 🇺🇸 US 🇨🇦 CA | Fail-SafeIncludes Housing, and Seal | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: 4.8L L4 DIESEL Turbocharged | 405785 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Popular Fits: 4.8L L4 DIESEL Turbocharged | 405680 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Popular Fits: 5.7L V8 | 265180 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| CALORSTAT Fits: all 2001 NPR engines | TH153882 | 🇺🇸 US 🇨🇦 CA | PerformanceDoes Not Include Seal | View on Amazon |
| CALORSTAT Fits: all 2001 NPR engines | THF153882 | 🇺🇸 US 🇨🇦 CA | High EfficiencyLarger Main Valve Seat | View on Amazon |
| CALORSTAT Fits: all 2001 NPR engines | TH153871 | 🇺🇸 US 🇨🇦 CA | PerformanceDoes Not Include Seal | View on Amazon |
| CALORSTAT Fits: all 2001 NPR engines | THF598191J | 🇺🇸 US 🇨🇦 CA | High EfficiencyLarger Main Valve Seat | View on Amazon |
| CALORSTAT Fits: all 2001 NPR engines | TH153891 | 🇺🇸 US 🇨🇦 CA | PerformanceDoes Not Include Seal | View on Amazon |
| GATES Fits: 5.7L V8 | 34769 | 🇺🇸 US 🇨🇦 CA | OE Exact | View on Amazon |
| MAHLE / CLEVITE Fits: 5.7L V8 | TX5292 | 🇺🇸 US 🇨🇦 CA | Includes Gasket or Seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 265195 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 265170 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 265160 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 5.7L V8 | 5169KT | 🇺🇸 US 🇨🇦 CA | Includes Housing, Thermostat and SealKit | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
27 Thermostat parts for the 2001 Isuzu NPR come from 4 brands — MOTORAD, CALORSTAT, GATES and 1 other brand. The "Popular" part is MOTORAD 5265195. Grades run from Heavy Duty through Standard Replacement; Standard Replacement is the most populated section, led by MOTORAD, CALORSTAT, GATES and 1 other brand.
Thermostat / Thermostat Housing / Water Outlet Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MAHLE / CLEVITE Fits: 5.7L V8 | C31273 | 🇺🇸 US 🇨🇦 CA | Molded Rubber | View on Amazon |
This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
One part is listed for the 2001 Isuzu NPR — MAHLE / CLEVITE C31273.
Thermostat Housing / Water Outlet
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 5.7L V8 | 902754 | 🇺🇸 US 🇨🇦 CA | Thermostat Housing | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: 5.7L V8 | CH5169 | 🇺🇸 US 🇨🇦 CA | Includes Gasket | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
2 Thermostat Housing / Water Outlet parts for the 2001 Isuzu NPR come from 2 brands — DORMAN and MOTORAD.
The Economy section: 1 option from DORMAN. DORMAN 902754 is listed in this group.
Standard Replacement: 1 part, from MOTORAD. A representative part number is MOTORAD CH5169.
Part numbers include DORMAN 902754 and MOTORAD CH5169.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Fits: 5.7L V8 | US5077 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| SKP Fits: 5.7L V8 | SK1301820 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| US MOTOR WORKS Fits: 5.7L V8 | US5077 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| WJB / INMOTION PARTS Fits: 5.7L V8 | WU5077 | 🇺🇸 US 🇨🇦 CA | From 10/1995 | View on Amazon |
High Volume / Pressure
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Fits: 5.7L V8 | US5077H | 🇺🇸 US 🇨🇦 CA | High Performance | View on Amazon |
| GMB Fits: 5.7L V8 | 1301820P | 🇺🇸 US 🇨🇦 CA | High Performance | View on Amazon |
| US MOTOR WORKS Fits: 5.7L V8 | US5077H | 🇺🇸 US 🇨🇦 CA | High Performance | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DAYCO Popular Fits: 5.7L V8 | DP957 | 🇺🇸 US 🇨🇦 CA | Serpentine Belt DrivenStandard Duty | View on Amazon |
| GATES Popular Fits: 5.7L V8 | 43315 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB Popular Fits: 5.7L V8 | 1301820 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DAYCO Fits: 5.7L V8 | DP957H | 🇺🇸 US 🇨🇦 CA | Heavy Duty | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
11 Water Pump parts for the 2001 Isuzu NPR come from 7 brands — FVP, US MOTOR WORKS, GMB and 4 other brands. The "Popular" part is DAYCO DP957.
The Economy section: 4 options from FVP, SKP, US MOTOR WORKS and 1 other brand. FVP US5077 is listed in this group.
The High Volume / Pressure section lists 3 options from FVP, GMB and US MOTOR WORKS — grouped under the catalog's "High Volume / Pressure" designation — the notes column spells out what sets them apart. FVP US5077H is listed in this group.
Standard Replacement: 4 parts, from DAYCO, GATES and GMB. A representative part number is DAYCO DP957.
Water Pump Gasket
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MAHLE / CLEVITE Fits: 5.7L V8 | K25935 | 🇺🇸 US 🇨🇦 CA | Paper | View on Amazon |
| MAHLE / CLEVITE Fits: 5.7L V8 | K27091 | 🇺🇸 US 🇨🇦 CA | Paper | View on Amazon |
This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.
MAHLE / CLEVITE supplies both parts for the 2001 Isuzu NPR.
Listed part numbers: MAHLE / CLEVITE K25935 and MAHLE / CLEVITE K27091.
Water Pump Stud Kit
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 5.7L V8 | 902804 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the Water Pump Stud kits.
This group shows a single part: DORMAN 902804.
Buying Cooling System Parts for a 2001 Isuzu NPR
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Thermostat and Radiator Hose .
Frequently Asked Questions
How many cooling system parts fit the 2001 Isuzu NPR?
Our catalog currently lists 114 cooling system parts for the 2001 Isuzu NPR across 17 subcategories and 29 brands, covering both the 4.8L L4 DIESEL Turbocharged and the 5.7L V8. Each part is matched to the engine(s) it fits.
Do cooling system parts differ between 2001 Isuzu NPR engines?
Some do. 37 parts fit every engine; the other 77 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.
What are the signs of cooling system problems on a 2001 Isuzu NPR?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2001 Isuzu NPR was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2001 Isuzu NPR?
First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2001 Isuzu NPR
Cooling System Parts for Other Isuzu NPR Years
Switch vehicle or jump to a subcategory
Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.