91 Cooling system parts are listed for the 2006 Isuzu NPR, in 13 part types, covering both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8. Each one has a brand, a manufacturer part number and notes that say where it fits.
On the 2006 Isuzu NPR, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 41 parts of the 91 listed are Coolant / Antifreeze (14 parts), Water Pump (14 parts) and Radiator Hose (13 parts). The other 10 part types cover the remaining 50 parts.
The 2006 Isuzu NPR was sold with both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8. 28 parts fit every engine; the other 63 are engine-specific. Each part shows which engine(s) it fits.
The most listed brands for 2006 Isuzu NPR cooling system parts are GATES (13 parts), MOTORAD (11 parts) and PRESTONE (6 parts), plus 25 more brands. Quality grades include Standard Replacement, Economy and Heavy Duty.
15 parts on this 2006 Isuzu NPR page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including FVP MV5050GAL (Coolant / Antifreeze) and CSF 3209 (Radiator). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2006 NPR engines | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Popular Fits: all 2006 NPR engines | MV5050GAL | 🇺🇸 US 🇨🇦 CA | Extended LifeAll Makes / All Models | View on Amazon |
| PEAK Fits: all 2006 NPR engines | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE Fits: all 2006 NPR engines | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE Fits: all 2006 NPR engines | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK Fits: all 2006 NPR engines | FXA1GAL | 🇺🇸 US 🇨🇦 CA | Final Charge Global1 Gallon | View on Amazon |
| PRESTONE Fits: all 2006 NPR engines | AFC13000 | 🇺🇸 US 🇨🇦 CA | Command COR-Guard Nitrite Free-Noat Extended Life CoolantRed | View on Amazon |
| PRESTONE Fits: all 2006 NPR engines | AFC12100 | 🇺🇸 US 🇨🇦 CA | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2006 NPR engines | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK Fits: all 2006 NPR engines | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK Fits: all 2006 NPR engines | PXA1GAL | 🇺🇸 US 🇨🇦 CA | 1 GallonGlobal Lifetime | View on Amazon |
| PRESTONE Fits: all 2006 NPR engines | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| VALVOLINE Popular Fits: all 2006 NPR engines | ZXEL1 | 🇺🇸 US 🇨🇦 CA | Dex-Cool Orange1 Gallon | View on Amazon |
| VALVOLINE Fits: all 2006 NPR engines | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
14 Coolant / Antifreeze parts for the 2006 Isuzu NPR come from 4 brands — PRESTONE, PEAK, VALVOLINE and 1 other brand. The "Popular" part is FVP MV5050GAL. Every part fits both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 4 options from FVP, PEAK, PRESTONE and 1 other brand — the catalog's value-priced group. FVP MV5050GAL is listed in this group.
In the Heavy Duty grade, PRESTONE and PEAK supply 3 parts: rated for severe service. A representative part number is PEAK FXA1GAL.
In the Premium grade, PRESTONE and PEAK supply 4 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, VALVOLINE supplies 2 parts: built to original-equipment specification. A representative part number is VALVOLINE ZXEL1.
Coolant Reservoir
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: all 2006 NPR engines | 6035603 | 🇺🇸 US 🇨🇦 CA | Fits NPR Base Modelor NPR-HDSingle Cab | View on Amazon |
This table covers the overflow / expansion tanks that hold extra coolant.
One part is listed for the 2006 Isuzu NPR — DORMAN 6035603.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: all 2006 NPR engines | 9241059 | 🇺🇸 US 🇨🇦 CA | Single Cab | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
One part is listed for the 2006 Isuzu NPR — DORMAN 9241059.
Cooling System Tester Adapter
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Fits: all 2006 NPR engines | 31428 | 🇺🇸 US 🇨🇦 CA | May Require Spacer Number 31416 | View on Amazon |
| MOTORAD Fits: all 2006 NPR engines | 3121 | 🇺🇸 US 🇨🇦 CA | StandardRadiator Cap Adapter | View on Amazon |
| MOTORAD Fits: all 2006 NPR engines | 3122 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
| STANT Fits: all 2006 NPR engines | 12021 | 🇺🇸 US 🇨🇦 CA | Radiator Cap/Cooling System Tester Adapter | View on Amazon |
This table covers the adapters used to pressure-test this cooling system.
4 Cooling System Tester Adapter parts for the 2006 Isuzu NPR come from 3 brands — MOTORAD, GATES and STANT. Every part fits both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8.
Listed part numbers: GATES 31428, MOTORAD 3121 and MOTORAD 3122, plus the other parts above.
Intercooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Fits: 5.2L L4 DIESEL Turbocharged | 6050 | 🇺🇸 US 🇨🇦 CA | Tube & Fin | View on Amazon |
| GPD Fits: 5.2L L4 DIESEL Turbocharged | 2711271 | 🇺🇸 US 🇨🇦 CA | with 21.63 IN X 14.5 IN X 2In Corewith 2.75 IN Inlet | View on Amazon |
| SPECTRA PREMIUM Fits: 5.2L L4 DIESEL Turbocharged | 44010707 | 🇺🇸 US 🇨🇦 CA | 21-5/8" X 14-1/2" X 2 in. Core2-3/4" Inlet / 2-3/4" Outlet | View on Amazon |
This table covers the intercoolers that cool turbo or supercharger charge air.
3 Intercooler parts for the 2006 Isuzu NPR come from 3 brands — CSF, GPD and SPECTRA PREMIUM.
Part numbers include CSF 6050, GPD 2711271 and SPECTRA PREMIUM 44010707.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD Fits: 5.2L L4 DIESEL Turbocharged | 9243219 | 🇺🇸 US 🇨🇦 CA | HD | View on Amazon |
| GPD Fits: 6.0L V8 | 9243243 | 🇺🇸 US 🇨🇦 CA | All MetalHeavy Duty | View on Amazon |
| GPD Fits: 6.0L V8 | 9282730 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| ULTRA-POWER Fits: 5.2L L4 DIESEL Turbocharged | 20010705 | 🇺🇸 US 🇨🇦 CA | 24-1/2" X 23-3/8" X 1-1/4" CoreInlet 1-1/2" Upper Left Side | View on Amazon |
Heavy Duty (All Metal Construction)
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Fits: 5.2L L4 DIESEL Turbocharged | 3219 | 🇺🇸 US 🇨🇦 CA | 3 RowAll Metal Model with Sensor Port On Top Tank. | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Popular Fits: 5.2L L4 DIESEL Turbocharged | 3209 | 🇺🇸 US 🇨🇦 CA | 1 RowPlastic Tank / Aluminum Core | View on Amazon |
| CSF Popular Fits: 6.0L V8 | 3242 | 🇺🇸 US 🇨🇦 CA | 1 RowPlastic Tank / Aluminum Core | View on Amazon |
| OSC Fits: all 2006 NPR engines | HD9217 | 🇺🇸 US 🇨🇦 CA | NPR Base Model24 7/16" Tall | View on Amazon |
| OSC Fits: 6.0L V8 | HD1176 | 🇺🇸 US 🇨🇦 CA | Fits NPR-HD | View on Amazon |
| UAC Fits: 6.0L V8 | RA5000C | 🇺🇸 US 🇨🇦 CA | Downflow | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| LILAND GLOBAL Fits: 6.0L V8 | 1000700 | 🇺🇸 US 🇨🇦 CA | Rad/CAC Assy | View on Amazon |
| LILAND GLOBAL Fits: 6.0L V8 | 2000700 | 🇺🇸 US 🇨🇦 CA | NPR Base ModelIsuzu NPR31 Step COE Truck | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
12 Radiator parts for the 2006 Isuzu NPR come from 6 brands — GPD, CSF, OSC and 3 other brands. The "Popular" part is CSF 3209. 1 part fits every engine; the other 11 are engine-specific.
The Economy section: 4 options from GPD and ULTRA-POWER. GPD 9243219 is listed in this group.
In the Heavy Duty (All Metal Construction) grade, CSF supplies 1 part: rated for severe service. A representative part number is CSF 3219.
Standard Replacement: 5 parts, from CSF, OSC and UAC. A representative part number is CSF 3209.
2 further parts sit outside the graded sections, with the same engine-level match.
Radiator Cap
Locking Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT Fits: all 2006 NPR engines | RC0212 | 🇺🇸 US 🇨🇦 CA | PerformanceIncludes 2 seals | View on Amazon |
| GATES Fits: all 2006 NPR engines | 31534 | 🇺🇸 US 🇨🇦 CA | Safety Release Radiator Cap | View on Amazon |
| MOTORAD Fits: all 2006 NPR engines | ST16R | 🇺🇸 US 🇨🇦 CA | Safety LeverIndicator Markings Color: Blue, Red | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: all 2006 NPR engines | T16R | 🇺🇸 US 🇨🇦 CA | StandardIndicator Markings Color: Silver | View on Amazon |
| SKP Popular Fits: all 2006 NPR engines | SK10233 | 🇺🇸 US 🇨🇦 CA | Pressure Rating 16 psi | View on Amazon |
| CSF Fits: all 2006 NPR engines | 4503 | 🇺🇸 US 🇨🇦 CA | Mini, 16 PSI | View on Amazon |
| GATES Fits: all 2006 NPR engines | 31336 | 🇺🇸 US 🇨🇦 CA | OE Type | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
7 Radiator Cap parts for the 2006 Isuzu NPR come from 5 brands — GATES, MOTORAD, CALORSTAT and 2 other brands. The "Popular" part is MOTORAD T16R. Every part fits both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8.
In the Locking Replacement grade, CALORSTAT, GATES and MOTORAD supply 3 parts: grouped under the catalog's "Locking Replacement" designation — the notes column spells out what sets them apart. A representative part number is CALORSTAT RC0212.
Standard Replacement: 4 parts, from MOTORAD, SKP, CSF and 1 other brand. A representative part number is MOTORAD T16R.
Listed part numbers: MOTORAD T16R, CALORSTAT RC0212 and GATES 31534, plus the other parts above.
Radiator Fan Clutch
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FOUR SEASONS Fits: 6.0L V8 | 36947 | 🇺🇸 US 🇨🇦 CA | Severe Duty Thermal | View on Amazon |
| HAYDEN Fits: 6.0L V8 | 2787 | 🇺🇸 US 🇨🇦 CA | ThermalSevere Duty | View on Amazon |
| NISSENS Fits: 6.0L V8 | 86465 | 🇺🇸 US 🇨🇦 CA | Severe Duty Thermal | View on Amazon |
| SKP Fits: 6.0L V8 | SK36947 | 🇺🇸 US 🇨🇦 CA | Thermal | View on Amazon |
This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.
4 Radiator Fan Clutch parts for the 2006 Isuzu NPR come from 4 brands — FOUR SEASONS, HAYDEN, NISSENS and 1 other brand.
Listed part numbers: FOUR SEASONS 36947, HAYDEN 2787 and NISSENS 86465, plus the other parts above.
Radiator Hose
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CONTINENTAL Popular Fits: 5.2L L4 DIESEL Turbocharged | 62699 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| DAYCO Popular Fits: 6.0L V8 | 71538 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| DAYCO Popular Fits: 6.0L V8 | 72193 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| GATES Popular Fits: 5.2L L4 DIESEL Turbocharged | 23096 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| ACDELCO Fits: 5.2L L4 DIESEL Turbocharged | 20456S | 🇺🇸 US 🇨🇦 CA | Professional / GoldMolded | View on Amazon |
| ACDELCO Fits: 5.2L L4 DIESEL Turbocharged | 24564L | 🇺🇸 US 🇨🇦 CA | Professional / GoldMolded | View on Amazon |
| CONTINENTAL Fits: 5.2L L4 DIESEL Turbocharged | 62807 | 🇺🇸 US 🇨🇦 CA | MoldedEnd 2 Hose Inside Diameter: 1.62 In | View on Amazon |
| CONTINENTAL Fits: 6.0L V8 | 66208 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| CONTINENTAL Fits: 6.0L V8 | 66009 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| DAYCO Fits: 5.2L L4 DIESEL Turbocharged | 72040 | 🇺🇸 US 🇨🇦 CA | Curved | View on Amazon |
| GATES Fits: 5.2L L4 DIESEL Turbocharged | 23095 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES Fits: 6.0L V8 | 23098 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES Fits: 6.0L V8 | 23097 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.
13 Radiator Hose parts are listed for the 2006 Isuzu NPR, from CONTINENTAL, GATES, DAYCO and 1 other brand. CONTINENTAL 62699 carries the "Popular" badge.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 6.0L V8 | 926016 | 🇺🇸 US | NPR-HD | View on Amazon |
| STANDARD MOTOR PRODUCTS Fits: 6.0L V8 | TX89T | 🇺🇸 US | T-Series | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| STANDARD MOTOR PRODUCTS Fits: 6.0L V8 | TX89 | 🇺🇸 US | NPR-HD | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
3 Temperature Sender / Sensor parts for the 2006 Isuzu NPR come from 2 brands — STANDARD MOTOR PRODUCTS and DORMAN.
The Economy section: 2 options from DORMAN and STANDARD MOTOR PRODUCTS. DORMAN 926016 is listed in this group.
Standard Replacement: 1 part, from STANDARD MOTOR PRODUCTS. A representative part number is STANDARD MOTOR PRODUCTS TX89.
This group includes DORMAN 926016, STANDARD MOTOR PRODUCTS TX89T and STANDARD MOTOR PRODUCTS TX89.
Thermostat
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 6.0L V8 | 9022836 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
| SKP Fits: 6.0L V8 | SK9022836 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Popular Fits: 6.0L V8 | 33963 | 🇺🇸 US 🇨🇦 CA | Heavy-Duty | View on Amazon |
| GATES Fits: 5.2L L4 DIESEL Turbocharged | 33964 | 🇺🇸 US 🇨🇦 CA | Heavy-Duty | View on Amazon |
| GATES Fits: 5.2L L4 DIESEL Turbocharged | 33965 | 🇺🇸 US 🇨🇦 CA | Heavy-Duty | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular Fits: 6.0L V8 | 456187 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 5.2L L4 DIESEL Turbocharged | 405785 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 5.2L L4 DIESEL Turbocharged | 405680 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD Fits: 6.0L V8 | 400995 | 🇺🇸 US 🇨🇦 CA | 195 Degrees FOE Specified Temperature 195 Degrees | View on Amazon |
| MOTORAD Fits: 6.0L V8 | 400980 | 🇺🇸 US 🇨🇦 CA | 180 Degrees FOE Specified Temperature | View on Amazon |
| MOTORAD Fits: 6.0L V8 | 524190 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
11 Thermostat parts are listed for the 2006 Isuzu NPR, from MOTORAD, GATES, DORMAN and 1 other brand. GATES 33963 carries the "Popular" badge.
Economy: 2 parts, from DORMAN and SKP. A representative part number is DORMAN 9022836.
The Heavy Duty section: 3 options from GATES. GATES 33963 is listed in this group.
The Standard Replacement section: 6 options from MOTORAD. MOTORAD 456187 is listed in this group.
Thermostat Housing / Water Outlet
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AUTOTECNICA Fits: 6.0L V8 | GM0718508 | 🇺🇸 US 🇨🇦 CA | UpperHousing Only | View on Amazon |
| DORMAN Fits: 6.0L V8 | 902836 | 🇺🇸 US 🇨🇦 CA | Does Not Include Thermostat | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Fits: 6.0L V8 | CO34923 | 🇺🇸 US 🇨🇦 CA | Thermostat CoverWater Outlet | View on Amazon |
| MOTORAD Fits: 6.0L V8 | CH2836 | 🇺🇸 US 🇨🇦 CA | Water Outlet | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
4 Thermostat Housing / Water Outlet parts are listed for the 2006 Isuzu NPR, from AUTOTECNICA, DORMAN, GATES and 1 other brand.
Economy: 2 parts, from AUTOTECNICA and DORMAN. A representative part number is AUTOTECNICA GM0718508.
The Standard Replacement section: 2 options from GATES and MOTORAD. GATES CO34923 is listed in this group.
Listed part numbers: AUTOTECNICA GM0718508, DORMAN 902836 and GATES CO34923, plus the other parts above.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SKP Popular Fits: 6.0L V8 | SK1307340 | 🇺🇸 US 🇨🇦 CA | without Thermostat | View on Amazon |
| US MOTOR WORKS Popular Fits: 6.0L V8 | US64 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FVP Fits: 6.0L V8 | US64 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FVP Fits: 6.0L V8 | US64T | 🇺🇸 US 🇨🇦 CA | Includes thermostat and thermostat housing | View on Amazon |
| SKP Fits: 6.0L V8 | SK1307340AT | 🇺🇸 US 🇨🇦 CA | Includes Thermostat & Flange | View on Amazon |
| US MOTOR WORKS Fits: 6.0L V8 | US64T | 🇺🇸 US 🇨🇦 CA | Includes Thermostat and Housing | View on Amazon |
High Volume / Pressure
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Fits: 5.2L L4 DIESEL Turbocharged | 42239HD | 🇺🇸 US 🇨🇦 CA | Water Pump (Heavy-Duty) | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Fits: 5.2L L4 DIESEL Turbocharged | WPG027 | 🇺🇸 US 🇨🇦 CA | No Gasket Required, Use "FIPG" Form In Place Gasket Sealant: AISIN #AB1207B1 | View on Amazon |
| DAYCO Fits: 6.0L V8 | DP998 | 🇺🇸 US 🇨🇦 CA | 47mm Thermostat DiameterSerpentine Belt Driven | View on Amazon |
| FVP Fits: 5.2L L4 DIESEL Turbocharged | 1401560 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GATES Fits: 6.0L V8 | 45005 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB Fits: 5.2L L4 DIESEL Turbocharged | 1401560 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB Fits: 6.0L V8 | 1307340 | 🇺🇸 US 🇨🇦 CA | 2.05" Diameter Thermostat Opening | View on Amazon |
| GMB Fits: 6.0L V8 | 1307340AT | 🇺🇸 US 🇨🇦 CA | Includes Thermostat | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
14 Water Pump parts are listed for the 2006 Isuzu NPR, from FVP, GMB, SKP and 4 other brands. SKP SK1307340 carries the "Popular" badge.
Economy: 6 parts, from SKP, US MOTOR WORKS and FVP. A representative part number is SKP SK1307340.
In the High Volume / Pressure grade, GATES supplies 1 part: grouped under the catalog's "High Volume / Pressure" designation — the notes column spells out what sets them apart. A representative part number is GATES 42239HD.
The Standard Replacement section: 7 options from GMB, AISIN, DAYCO and 2 other brands. AISIN WPG027 is listed in this group.
Buying Cooling System Parts for a 2006 Isuzu NPR
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2006 Isuzu NPR?
Our catalog currently lists 91 cooling system parts for the 2006 Isuzu NPR across 13 subcategories and 28 brands, covering both the 5.2L L4 DIESEL Turbocharged and the 6.0L V8. Each part is matched to the engine(s) it fits.
Do cooling system parts differ between 2006 Isuzu NPR engines?
Some do. 28 parts fit every engine; the other 63 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.
What are the signs of cooling system problems on a 2006 Isuzu NPR?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2006 Isuzu NPR was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2006 Isuzu NPR?
First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2006 Isuzu NPR
Cooling System Parts for Other Isuzu NPR Years
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