2021 Lexus ES250 Cooling System Parts

Engine:
2.5L L4

The 2021 Lexus ES250 has 73 cooling system parts with verified fitment on this page — 14 part types and 34 brands, covering the 2.5L L4 engine. Each part includes a manufacturer part number and application notes.

On the 2021 Lexus ES250, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 32 parts of the 73 listed are Coolant / Antifreeze (16 parts), Radiator (9 parts) and Radiator Fan Assembly (7 parts). The other 11 part types cover the remaining 41 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE AF3055
🇺🇸 US 🇨🇦 CA
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
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Economy

Brand Part Number Markets Notes Buy
FVP Popular MV5050GAL
🇺🇸 US 🇨🇦 CA
Extended LifeAll Makes / All Models
Fitment notes — FVP MV5050GAL
Extended LifeAll Makes / All Models1 Gallon
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PEAK BQA1GAL
🇺🇸 US 🇨🇦 CA
Blue Mountain Long LifeAll Vehicle
Fitment notes — PEAK BQA1GAL
Blue Mountain Long LifeAll Vehicle1 Gallon
The OE antifreeze color For this application Can be Red or pink.
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PRESTONE AF3100
🇺🇸 US 🇨🇦 CA
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
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VALVOLINE 719009
🇺🇸 US 🇨🇦 CA
Multi-Vehicle Yellow1 Gallon
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular AF2100
🇺🇸 US 🇨🇦 CA
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
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PEAK PKP1GAL
🇺🇸 US 🇨🇦 CA
All Vehicles Antifreeze1 Gallon
Fitment notes — PEAK PKP1GAL
All Vehicles Antifreeze1 GallonPREMIUM1 GALLON10X MORE SCALE FIGHTING INHIBITORS10 YEAR/300K MILES
The OE antifreeze color For this application Can be Red or pink.
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PEAK PXA1GAL
🇺🇸 US 🇨🇦 CA
Global Lifetime1 Gallon
Fitment notes — PEAK PXA1GAL
Global Lifetime1 Gallon
The OE antifreeze color For this application Can be Red or pink.
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PRESTONE AF6210
🇺🇸 US 🇨🇦 CA
MAX Original EquipmentAsian Red/Pink
Fitment notes — PRESTONE AF6210
MAX Original EquipmentAsian Red/PinkReady To Use 1 Gallon
(Type: Prediluted)
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PRESTONE AFMAX
🇺🇸 US 🇨🇦 CA
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular ACT002
🇺🇸 US 🇨🇦 CA
PinkHOAT
Fitment notes — AISIN ACT002
PinkHOAT
(Type: Prediluted)
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VALVOLINE Popular 675130
🇺🇸 US 🇨🇦 CA
Asian Vehicle Red1 Gallon
Fitment notes — VALVOLINE 675130
Asian Vehicle Red1 GallonPOAT
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BECK/ARNLEY 2521502
🇺🇸 US 🇨🇦 CA
Premium Extra Life Pink
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BECK/ARNLEY 2521002
🇺🇸 US 🇨🇦 CA
Premium Red
Fitment notes — BECK/ARNLEY 2521002
Premium Red
252-1502 Pink premix Can be used with or In place of Red (Type: Concentrated)
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PEAK PAR1GAL
🇺🇸 US 🇨🇦 CA
OET Asian Extended Life Red1 Gallon
Fitment notes — PEAK PAR1GAL
OET Asian Extended Life Red1 Gallon
The OE antifreeze color For this application Can be Red or pink.OE Match, This product is compatible with Asian Red and pink antifreeze.
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PENTOSIN 8115209
🇺🇸 US 🇨🇦 CA
Pentofrost A41 Gallon
Fitment notes — PENTOSIN 8115209
Pentofrost A41 GallonPink
(Type: Prediluted)
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Hose Connector / Flange Seal

Brand Part Number Markets Notes Buy
ELRING 106660
🇺🇸 US 🇨🇦 CA
Base ModelBody code: AXZA15
Fitment notes — ELRING 106660
Base ModelBody code: AXZA15Inlet Flange Seal
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This table covers the seals at the Coolant Hose Connector / Flange. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Coolant Reservoir

Brand Part Number Markets Notes Buy
TECHPRO TO3014138
🇺🇸 US 🇨🇦 CA
Assembly
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This table covers the overflow / expansion tanks that hold extra coolant.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
MOTORAD T125
🇺🇸 US 🇨🇦 CA
Includes HosesStandard
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator

Economy

Brand Part Number Markets Notes Buy
TECHPRO TO3010364
🇺🇸 US 🇨🇦 CA
View on
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Standard Replacement

Brand Part Number Markets Notes Buy
CSF Popular 3858
🇺🇸 US 🇨🇦 CA
Upgraded with Higher Performance & Stronger B-Tube Design
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TYC Popular 13670
🇺🇸 US 🇨🇦 CA
View on
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AGILITY 8013670
🇺🇸 US 🇨🇦 CA
MAIN RADIATOR
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DENSO 2219627
🇺🇸 US 🇨🇦 CA
View on
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NISSENS 606786
🇺🇸 US 🇨🇦 CA
Brazed cooling fins
Fitment notes — NISSENS 606786
Brazed cooling fins
Base Model or F Sport or Luxury or Ultra Luxury
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OSC 13670
🇺🇸 US 🇨🇦 CA
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SPECTRA PREMIUM CU13670
🇺🇸 US 🇨🇦 CA
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UAC RA13670C
🇺🇸 US 🇨🇦 CA
Base Model or F Sport or Luxury or Ultra Luxury
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Locking Replacement

Brand Part Number Markets Notes Buy
MOTORAD ST36
🇺🇸 US 🇨🇦 CA
Safety Lever
Fitment notes — MOTORAD ST36
Safety Lever
Relief Pressure 13 lbs
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Amazon

Standard Replacement

Brand Part Number Markets Notes Buy
GATES Popular 31411
🇺🇸 US 🇨🇦 CA
OE Type
Fitment notes — GATES 31411
OE Type
13 psi Pressure Rating
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CALORSTAT RC0047
🇺🇸 US 🇨🇦 CA
Includes 2 sealsMetallic
Fitment notes — CALORSTAT RC0047
Includes 2 sealsMetallicDegassing function
PSI - 16.0
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MOTORAD T36
🇺🇸 US 🇨🇦 CA
Standard
Fitment notes — MOTORAD T36
Standard
Relief Pressure 13 lbs
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SKP SK10241
🇺🇸 US 🇨🇦 CA
Pressure Rating 13 psi
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Assembly

Economy

Brand Part Number Markets Notes Buy
GPD 2812044
🇺🇸 US 🇨🇦 CA
View on
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VARIOUS MFR TO3115202
🇺🇸 US 🇨🇦 CA
View on
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Standard Replacement

Brand Part Number Markets Notes Buy
AGILITY Popular 6010458
🇺🇸 US 🇨🇦 CA
Single Fan Replacement
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TYC Popular 624200
🇺🇸 US 🇨🇦 CA
Base Model or F Sport or Luxury or Ultra Luxury
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ACKOJA A70010011
🇺🇸 US 🇨🇦 CA
Includes Fan Blade & Motor
Fitment notes — ACKOJA A70010011
Includes Fan Blade & Motor
Base Model or F Sport or Luxury or Ultra Luxurywith OE No. 16360F0010
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FOUR SEASONS 75186
🇺🇸 US 🇨🇦 CA
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UAC FA50635C
🇺🇸 US 🇨🇦 CA
View on
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This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.

Radiator Hose

Brand Part Number Markets Notes Buy
CONTINENTAL 62145
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — CONTINENTAL 62145
Molded
Lower
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GATES 52064
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 52064
Molded
Lower
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GATES 51815
🇺🇸 US 🇨🇦 CA
Molded
Fitment notes — GATES 51815
Molded
Upper
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This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
GPD 1712504
🇺🇸 US 🇨🇦 CA
Engine Block
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular THSAZ8004
🇺🇸 US 🇨🇦 CA
View on
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STANDARD MOTOR PRODUCTS Popular TX319
🇺🇸 US 🇨🇦 CA
Located on Intake Manifold
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BECK/ARNLEY 1581797
🇺🇸 US 🇨🇦 CA
View on
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WALKER PRODUCTS 2112017
🇺🇸 US 🇨🇦 CA
Sensor Only
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WELLS 5S17570
🇺🇸 US 🇨🇦 CA
View on
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Thermostat

Economy

Brand Part Number Markets Notes Buy
AUTOTECNICA TY0719461
🇺🇸 US 🇨🇦 CA
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular THT023
🇺🇸 US 🇨🇦 CA
82°C
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MOTORAD Popular 1115180
🇺🇸 US 🇨🇦 CA
Includes Housing, Gasket
Fitment notes — MOTORAD 1115180
Includes Housing, Gasket
180 Degrees FOE Specified Temperature
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BECK/ARNLEY 1430982
🇺🇸 US 🇨🇦 CA
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FOUR SEASONS 86328
🇺🇸 US 🇨🇦 CA
Includes Housing
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MAHLE / CLEVITE TI37482D
🇺🇸 US 🇨🇦 CA
Integral Thermostat
Fitment notes — MAHLE / CLEVITE TI37482D
Integral Thermostat
82CStart to Open Temperature: with Seal
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This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.

Thermostat / Thermostat Housing / Water Outlet Seal

Brand Part Number Markets Notes Buy
ELRING 306360
🇺🇸 US 🇨🇦 CA
Base ModelBody code: AXZA15
Fitment notes — ELRING 306360
Base ModelBody code: AXZA15Thermostat Seal
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This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Thermostat Housing / Water Outlet

Economy

Brand Part Number Markets Notes Buy
SKP Popular SK86328
🇺🇸 US 🇨🇦 CA
Thermostat Housing
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Standard Replacement

Brand Part Number Markets Notes Buy
GATES Popular CO35076
🇺🇸 US 🇨🇦 CA
Seal IncludedWater Outlet
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FOUR SEASONS 86369
🇺🇸 US 🇨🇦 CA
Water Outlet
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GATES CO35042
🇺🇸 US 🇨🇦 CA
Water Outlet
Fitment notes — GATES CO35042
Water Outlet
Seal included
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MOTORAD CH2099
🇺🇸 US 🇨🇦 CA
Includes Seal
Fitment notes — MOTORAD CH2099
Includes Seal
LeftLocated on Cylinder HeadWater Outlet
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MOTORAD CH2094
🇺🇸 US 🇨🇦 CA
Cylinder HeadWater Outlet
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MOTORAD CH1053
🇺🇸 US 🇨🇦 CA
RightLocated in Block
Fitment notes — MOTORAD CH1053
RightLocated in BlockWater Outlet
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This table covers the housings and outlets the thermostat sits in.

Water Pump

Economy

Brand Part Number Markets Notes Buy
SKP Popular SKWP8233
🇺🇸 US 🇨🇦 CA
View on
Amazon

Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular WPT207
🇺🇸 US 🇨🇦 CA
View on
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GMB 1709040
🇺🇸 US 🇨🇦 CA
View on
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Brand Part Number Markets Notes Buy
FVP 1709040
🇺🇸 US 🇨🇦 CA
Water Pump Drive Type: Electric
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FVP US8233
🇺🇸 US 🇨🇦 CA
Base Model or F Sport or Luxury or Ultra LuxuryPump Only
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FVP US82332
🇺🇸 US 🇨🇦 CA
Includes Back Housing
Fitment notes — FVP US82332
Includes Back Housing
Base Model or F Sport or Luxury or Ultra Luxury
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US MOTOR WORKS US8233
🇺🇸 US 🇨🇦 CA
Base Model or F Sport or Luxury or Ultra Luxury
View on
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This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.

Water Pump Gasket

Brand Part Number Markets Notes Buy
ELRING 917940
🇺🇸 US 🇨🇦 CA
Material: EPDM ethylene propylene diene Monomer (M-class) rubber
Fitment notes — ELRING 917940
Material: EPDM ethylene propylene diene Monomer (M-class) rubber
Base ModelBody code: AXZA15
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MAHLE / CLEVITE K33776
🇺🇸 US 🇨🇦 CA
Molded Rubber
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VICTOR REINZ 711790100
🇺🇸 US 🇨🇦 CA
View on
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This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Buying Cooling System Parts for a 2021 Lexus ES250

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Confirm you have the 2.5L L4 engine — every part on this page is matched to it.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Coolant / Antifreeze and Radiator .

Frequently Asked Questions

How many cooling system parts fit the 2021 Lexus ES250?

Our catalog currently lists 73 cooling system parts for the 2021 Lexus ES250 across 14 subcategories and 34 brands, covering the 2.5L L4 engine. Each part is matched to the engine(s) it fits.

What are the signs of cooling system problems on a 2021 Lexus ES250?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Lexus ES250 was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2021 Lexus ES250?

Every part on this page is matched to the 2.5L L4 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2021 Lexus ES250

Cooling System Parts for Other Lexus ES250 Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.