The 2021 Lexus ES250 has 73 cooling system parts with verified fitment on this page — 14 part types and 34 brands, covering the 2.5L L4 engine. Each part includes a manufacturer part number and application notes.
On the 2021 Lexus ES250, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 32 parts of the 73 listed are Coolant / Antifreeze (16 parts), Radiator (9 parts) and Radiator Fan Assembly (7 parts). The other 11 part types cover the remaining 41 parts.
The 2021 Lexus ES250 came with a single engine, the 2.5L L4, and every part is verified against it.
34 brands supply cooling system parts for the 2021 Lexus ES250, led by MOTORAD (7 parts), PRESTONE (5 parts) and GATES (5 parts), plus 31 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2021 Lexus ES250. 17 parts have it, including FVP MV5050GAL (Coolant / Antifreeze) and CSF 3858 (Radiator). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Popular | MV5050GAL | 🇺🇸 US 🇨🇦 CA | Extended LifeAll Makes / All Models | View on Amazon |
| PEAK | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK | PXA1GAL | 🇺🇸 US 🇨🇦 CA | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA | PinkHOAT | View on Amazon |
| VALVOLINE Popular | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
| BECK/ARNLEY | 2521502 | 🇺🇸 US 🇨🇦 CA | Premium Extra Life Pink | View on Amazon |
| BECK/ARNLEY | 2521002 | 🇺🇸 US 🇨🇦 CA | Premium Red | View on Amazon |
| PEAK | PAR1GAL | 🇺🇸 US 🇨🇦 CA | OET Asian Extended Life Red1 Gallon | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA | Pentofrost A41 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
16 Coolant / Antifreeze parts are listed for the 2021 Lexus ES250, from PRESTONE, PEAK, VALVOLINE and 4 other brands. FVP MV5050GAL carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, FVP, PEAK, PRESTONE and 1 other brand supply 4 parts: the catalog's value-priced group. A representative part number is FVP MV5050GAL.
The Premium section lists 5 options from PRESTONE and PEAK — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 6 options from BECK/ARNLEY, AISIN, VALVOLINE and 2 other brands — built to original-equipment specification. AISIN ACT002 is listed in this group.
Coolant Hose Connector / Flange Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING | 106660 | 🇺🇸 US 🇨🇦 CA | Base ModelBody code: AXZA15 | View on Amazon |
This table covers the seals at the Coolant Hose Connector / Flange. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
This group shows a single part: ELRING 106660.
Coolant Reservoir
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO | TO3014138 | 🇺🇸 US 🇨🇦 CA | Assembly | View on Amazon |
This table covers the overflow / expansion tanks that hold extra coolant.
This group shows a single part: TECHPRO TO3014138.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD | T125 | 🇺🇸 US 🇨🇦 CA | Includes HosesStandard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: MOTORAD T125.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO | TO3010364 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Popular | 3858 | 🇺🇸 US 🇨🇦 CA | Upgraded with Higher Performance & Stronger B-Tube Design | View on Amazon |
| TYC Popular | 13670 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| AGILITY | 8013670 | 🇺🇸 US 🇨🇦 CA | MAIN RADIATOR | View on Amazon |
| DENSO | 2219627 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| NISSENS | 606786 | 🇺🇸 US 🇨🇦 CA | Brazed cooling fins | View on Amazon |
| OSC | 13670 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| SPECTRA PREMIUM | CU13670 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UAC | RA13670C | 🇺🇸 US 🇨🇦 CA | Base Model or F Sport or Luxury or Ultra Luxury | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
9 Radiator parts are listed for the 2021 Lexus ES250, from TECHPRO, CSF, TYC and 6 other brands. CSF 3858 carries the "Popular" badge.
Economy: 1 part, from TECHPRO. A representative part number is TECHPRO TO3010364.
The Standard Replacement section: 8 options from CSF, TYC, AGILITY and 5 other brands. CSF 3858 is listed in this group.
Listed part numbers: CSF 3858, TECHPRO TO3010364 and TYC 13670, plus the other parts above.
Radiator Cap
Locking Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD | ST36 | 🇺🇸 US 🇨🇦 CA | Safety Lever | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Popular | 31411 | 🇺🇸 US 🇨🇦 CA | OE Type | View on Amazon |
| CALORSTAT | RC0047 | 🇺🇸 US 🇨🇦 CA | Includes 2 sealsMetallic | View on Amazon |
| MOTORAD | T36 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
| SKP | SK10241 | 🇺🇸 US 🇨🇦 CA | Pressure Rating 13 psi | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
5 Radiator Cap parts are listed for the 2021 Lexus ES250, from MOTORAD, GATES, CALORSTAT and 1 other brand. GATES 31411 carries the "Popular" badge.
The Locking Replacement section lists 1 option from MOTORAD — grouped under the catalog's "Locking Replacement" designation — the notes column spells out what sets them apart. MOTORAD ST36 is listed in this group.
The Standard Replacement section: 4 options from GATES, CALORSTAT, MOTORAD and 1 other brand. GATES 31411 is listed in this group.
Listed part numbers: GATES 31411, MOTORAD ST36 and CALORSTAT RC0047, plus the other parts above.
Radiator Fan Assembly
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 2812044 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| VARIOUS MFR | TO3115202 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AGILITY Popular | 6010458 | 🇺🇸 US 🇨🇦 CA | Single Fan Replacement | View on Amazon |
| TYC Popular | 624200 | 🇺🇸 US 🇨🇦 CA | Base Model or F Sport or Luxury or Ultra Luxury | View on Amazon |
| ACKOJA | A70010011 | 🇺🇸 US 🇨🇦 CA | Includes Fan Blade & Motor | View on Amazon |
| FOUR SEASONS | 75186 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UAC | FA50635C | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
7 Radiator Fan Assembly parts for the 2021 Lexus ES250 come from 7 brands — GPD, VARIOUS MFR, AGILITY and 4 other brands. The "Popular" part is AGILITY 6010458.
The Economy section: 2 options from GPD and VARIOUS MFR. GPD 2812044 is listed in this group.
Standard Replacement: 5 parts, from AGILITY, TYC, ACKOJA and 2 other brands. A representative part number is AGILITY 6010458.
Part numbers include AGILITY 6010458, GPD 2812044 and VARIOUS MFR TO3115202, among others listed above.
Radiator Hose
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CONTINENTAL | 62145 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES | 52064 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
| GATES | 51815 | 🇺🇸 US 🇨🇦 CA | Molded | View on Amazon |
This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.
3 Radiator Hose parts for the 2021 Lexus ES250 come from 2 brands — GATES and CONTINENTAL.
Part numbers include CONTINENTAL 62145, GATES 52064 and GATES 51815.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1712504 | 🇺🇸 US 🇨🇦 CA | Engine Block | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | THSAZ8004 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| STANDARD MOTOR PRODUCTS Popular | TX319 | 🇺🇸 US 🇨🇦 CA | Located on Intake Manifold | View on Amazon |
| BECK/ARNLEY | 1581797 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| WALKER PRODUCTS | 2112017 | 🇺🇸 US 🇨🇦 CA | Sensor Only | View on Amazon |
| WELLS | 5S17570 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
6 Temperature Sender / Sensor parts are listed for the 2021 Lexus ES250, from GPD, AISIN, STANDARD MOTOR PRODUCTS and 3 other brands. AISIN THSAZ8004 carries the "Popular" badge.
Economy: 1 part, from GPD. A representative part number is GPD 1712504.
The Standard Replacement section: 5 options from AISIN, STANDARD MOTOR PRODUCTS, BECK/ARNLEY and 2 other brands. AISIN THSAZ8004 is listed in this group.
This group includes AISIN THSAZ8004, GPD 1712504 and STANDARD MOTOR PRODUCTS TX319 and the remaining parts above.
Thermostat
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AUTOTECNICA | TY0719461 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | THT023 | 🇺🇸 US 🇨🇦 CA | 82°C | View on Amazon |
| MOTORAD Popular | 1115180 | 🇺🇸 US 🇨🇦 CA | Includes Housing, Gasket | View on Amazon |
| BECK/ARNLEY | 1430982 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FOUR SEASONS | 86328 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
| MAHLE / CLEVITE | TI37482D | 🇺🇸 US 🇨🇦 CA | Integral Thermostat | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
6 Thermostat parts for the 2021 Lexus ES250 come from 6 brands — AUTOTECNICA, AISIN, MOTORAD and 3 other brands. The "Popular" part is AISIN THT023.
The Economy section: 1 option from AUTOTECNICA. AUTOTECNICA TY0719461 is listed in this group.
Standard Replacement: 5 parts, from AISIN, MOTORAD, BECK/ARNLEY and 2 other brands. A representative part number is AISIN THT023.
Listed part numbers: AISIN THT023, AUTOTECNICA TY0719461 and MOTORAD 1115180, plus the other parts above.
Thermostat / Thermostat Housing / Water Outlet Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING | 306360 | 🇺🇸 US 🇨🇦 CA | Base ModelBody code: AXZA15 | View on Amazon |
This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
One part is listed for the 2021 Lexus ES250 — ELRING 306360.
Thermostat Housing / Water Outlet
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SKP Popular | SK86328 | 🇺🇸 US 🇨🇦 CA | Thermostat Housing | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Popular | CO35076 | 🇺🇸 US 🇨🇦 CA | Seal IncludedWater Outlet | View on Amazon |
| FOUR SEASONS | 86369 | 🇺🇸 US 🇨🇦 CA | Water Outlet | View on Amazon |
| GATES | CO35042 | 🇺🇸 US 🇨🇦 CA | Water Outlet | View on Amazon |
| MOTORAD | CH2099 | 🇺🇸 US 🇨🇦 CA | Includes Seal | View on Amazon |
| MOTORAD | CH2094 | 🇺🇸 US 🇨🇦 CA | Cylinder HeadWater Outlet | View on Amazon |
| MOTORAD | CH1053 | 🇺🇸 US 🇨🇦 CA | RightLocated in Block | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
7 Thermostat Housing / Water Outlet parts for the 2021 Lexus ES250 come from 4 brands — MOTORAD, GATES, SKP and 1 other brand. The "Popular" part is SKP SK86328.
The Economy section: 1 option from SKP. SKP SK86328 is listed in this group.
Standard Replacement: 6 parts, from MOTORAD, GATES and FOUR SEASONS. A representative part number is GATES CO35076.
This group includes SKP SK86328, GATES CO35076 and FOUR SEASONS 86369 and the remaining parts above.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SKP Popular | SKWP8233 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | WPT207 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB | 1709040 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP | 1709040 | 🇺🇸 US 🇨🇦 CA | Water Pump Drive Type: Electric | View on Amazon |
| FVP | US8233 | 🇺🇸 US 🇨🇦 CA | Base Model or F Sport or Luxury or Ultra LuxuryPump Only | View on Amazon |
| FVP | US82332 | 🇺🇸 US 🇨🇦 CA | Includes Back Housing | View on Amazon |
| US MOTOR WORKS | US8233 | 🇺🇸 US 🇨🇦 CA | Base Model or F Sport or Luxury or Ultra Luxury | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
7 Water Pump parts for the 2021 Lexus ES250 come from 5 brands — FVP, SKP, AISIN and 2 other brands. The "Popular" part is SKP SKWP8233.
The Economy section: 1 option from SKP. SKP SKWP8233 is listed in this group.
Standard Replacement: 2 parts, from AISIN and GMB. A representative part number is AISIN WPT207.
4 further parts sit outside the graded sections, with the same engine-level match.
Listed part numbers: SKP SKWP8233, AISIN WPT207 and GMB 1709040, plus the other parts above.
Water Pump Gasket
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ELRING | 917940 | 🇺🇸 US 🇨🇦 CA | Material: EPDM ethylene propylene diene Monomer (M-class) rubber | View on Amazon |
| MAHLE / CLEVITE | K33776 | 🇺🇸 US 🇨🇦 CA | Molded Rubber | View on Amazon |
| VICTOR REINZ | 711790100 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.
3 Water Pump Gasket parts are listed for the 2021 Lexus ES250, from ELRING, MAHLE / CLEVITE and VICTOR REINZ.
This group includes ELRING 917940, MAHLE / CLEVITE K33776 and VICTOR REINZ 711790100.
Buying Cooling System Parts for a 2021 Lexus ES250
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 2.5L L4 engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Radiator .
Frequently Asked Questions
How many cooling system parts fit the 2021 Lexus ES250?
Our catalog currently lists 73 cooling system parts for the 2021 Lexus ES250 across 14 subcategories and 34 brands, covering the 2.5L L4 engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2021 Lexus ES250?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Lexus ES250 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2021 Lexus ES250?
Every part on this page is matched to the 2.5L L4 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2021 Lexus ES250
Cooling System Parts for Other Lexus ES250 Years
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