32 Cooling system parts are listed for the 2022 Lexus LS500H, in 4 part types, covering the 3.5L V6 ELECTRIC/GAS engine. Each one has a brand, a manufacturer part number and notes that say where it fits.
The cooling system system on the 2022 Lexus LS500H keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (16 parts), Water Pump (10 parts) and Temperature Sender / Sensor (5 parts). The other 1 part type covers the remaining 1 part.
The 2022 Lexus LS500H came with a single engine, the 3.5L V6 ELECTRIC/GAS, and every part is verified against it.
17 brands supply cooling system parts for the 2022 Lexus LS500H, led by PRESTONE (5 parts), PEAK (4 parts) and AISIN (4 parts), plus 14 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2022 Lexus LS500H. 7 parts have it, including PRESTONE AF2100 (Coolant / Antifreeze) and AISIN THSAZ8003 (Temperature Sender / Sensor). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK | BQA1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles10yr/300k mi | View on Amazon |
| PEAK | PKP1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK | PXA1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | PinkHOAT | View on Amazon |
| BECK/ARNLEY Popular | 2521502 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Premium Extra Life Pink | View on Amazon |
| VALVOLINE Popular | 675130 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Asian Vehicle Red1 Gallon | View on Amazon |
| BECK/ARNLEY | 2521002 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Premium Red | View on Amazon |
| PEAK | PAR1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | OET Asian Extended Life Red1 Gallon | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 898406 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Hybrid Vehicle1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
16 Coolant / Antifreeze parts are listed for the 2022 Lexus LS500H, from PRESTONE, PEAK, VALVOLINE and 3 other brands. PRESTONE AF2100 carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, PEAK, PRESTONE and VALVOLINE supply 3 parts: the catalog's value-priced group. A representative part number is PEAK BQA1GAL.
The Premium section lists 5 options from PRESTONE and PEAK — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 7 options from BECK/ARNLEY, VALVOLINE, AISIN and 2 other brands — built to original-equipment specification. AISIN ACT002 is listed in this group.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0145 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Attachment Type: Threaded | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: CALORSTAT RC0145.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814549 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | THSAZ8003 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| BECK/ARNLEY | 1581802 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| DELPHI | TS10626 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| WALKER PRODUCTS | 2112012 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Sensor Only | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
5 Temperature Sender / Sensor parts are listed for the 2022 Lexus LS500H, from GPD, AISIN, BECK/ARNLEY and 2 other brands. AISIN THSAZ8003 carries the "Popular" badge.
Economy: 1 part, from GPD. A representative part number is GPD 1814549.
The Standard Replacement section: 4 options from AISIN, BECK/ARNLEY, DELPHI and 1 other brand. AISIN THSAZ8003 is listed in this group.
Listed part numbers: AISIN THSAZ8003, GPD 1814549 and BECK/ARNLEY 1581802, plus the other parts above.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| BECK/ARNLEY | 1312538 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| FVP | US8150 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| SKP | SK1703020 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| US MOTOR WORKS | US8150 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | WPT808 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| GATES Popular | 43424 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| AISIN | WQT006 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | AuxiliaryInverter Cooler Water Pump | View on Amazon |
| DAYCO | DP2182 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| FOUR SEASONS | 89072 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | AuxiliaryInverter Cooler Water Pump | View on Amazon |
| GMB | 1703020 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
10 Water Pump parts for the 2022 Lexus LS500H come from 9 brands — AISIN, BECK/ARNLEY, FVP and 6 other brands. The "Popular" part is AISIN WPT808.
The Economy section: 4 options from BECK/ARNLEY, FVP, SKP and 1 other brand. BECK/ARNLEY 1312538 is listed in this group.
Standard Replacement: 6 parts, from AISIN, GATES, DAYCO and 2 other brands. A representative part number is AISIN WPT808.
Buying Cooling System Parts for a 2022 Lexus LS500H
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.5L V6 ELECTRIC/GAS engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2022 Lexus LS500H?
Our catalog currently lists 32 cooling system parts for the 2022 Lexus LS500H across 4 subcategories and 17 brands, covering the 3.5L V6 ELECTRIC/GAS engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2022 Lexus LS500H?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2022 Lexus LS500H was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2022 Lexus LS500H?
Every part on this page is matched to the 3.5L V6 ELECTRIC/GAS engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2022 Lexus LS500H
Cooling System Parts for Other Lexus LS500H Years
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