This page lists 28 cooling system parts for the 2024 Lexus IS350, across 6 part types, covering the 3.5L V6 engine. Every part shows its brand, manufacturer part number and fitment notes.
On the 2024 Lexus IS350, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Coolant / Antifreeze (15 parts), Temperature Sender / Sensor (4 parts) and Coolant Reservoir Cap (3 parts). The other 3 part types cover the remaining 6 parts.
The 2024 Lexus IS350 came with a single engine, the 3.5L V6, and every part is verified against it.
17 brands supply cooling system parts for the 2024 Lexus IS350, led by PRESTONE (5 parts), PEAK (4 parts) and VALVOLINE (2 parts), plus 14 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2024 Lexus IS350. 3 parts have it, including PRESTONE AF2100 (Coolant / Antifreeze) and AISIN ACT002 (Coolant / Antifreeze). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK | PXA1GAL | 🇺🇸 US 🇨🇦 CA | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA | PinkHOAT | View on Amazon |
| VALVOLINE Popular | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
| BECK/ARNLEY | 2521502 | 🇺🇸 US 🇨🇦 CA | Premium Extra Life Pink | View on Amazon |
| BECK/ARNLEY | 2521002 | 🇺🇸 US 🇨🇦 CA | Premium Red | View on Amazon |
| PEAK | PAR1GAL | 🇺🇸 US 🇨🇦 CA | OET Asian Extended Life Red1 Gallon | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA | Pentofrost A41 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
15 Coolant / Antifreeze parts are listed for the 2024 Lexus IS350, from PRESTONE, PEAK, VALVOLINE and 3 other brands. PRESTONE AF2100 carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, PEAK, PRESTONE and VALVOLINE supply 3 parts: the catalog's value-priced group. A representative part number is PEAK BQA1GAL.
The Premium section lists 5 options from PRESTONE and PEAK — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 6 options from BECK/ARNLEY, AISIN, VALVOLINE and 2 other brands — built to original-equipment specification. AISIN ACT002 is listed in this group.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0145 | 🇺🇸 US 🇨🇦 CA | Attachment Type: Threaded | View on Amazon |
| GATES | 31541 | 🇺🇸 US 🇨🇦 CA | OE TypeThreaded (Closed System) - (SAE Range 18-20 psi) | View on Amazon |
| MOTORAD | T51 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
3 Coolant Reservoir Cap parts for the 2024 Lexus IS350 come from 3 brands — CALORSTAT, GATES and MOTORAD.
This group includes CALORSTAT RC0145, GATES 31541 and MOTORAD T51.
Cooling Fan Control Module
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES | FCM111 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the Cooling Fan control modules.
This group shows a single part: GATES FCM111.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 13776C | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| TECHPRO | LX3010165 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TYC | 13776 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
3 Radiator parts are listed for the 2024 Lexus IS350, from GPD, TECHPRO and TYC.
Economy: 2 parts, from GPD and TECHPRO. A representative part number is GPD 13776C.
The Standard Replacement section: 1 option from TYC. TYC 13776 is listed in this group.
Listed part numbers: GPD 13776C, TECHPRO LX3010165 and TYC 13776.
Radiator Fan Assembly
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AGILITY | 6010036 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UAC | FA50658C | 🇺🇸 US 🇨🇦 CA | Radiator-Condenser Fan Assembly | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
2 Radiator Fan Assembly parts for the 2024 Lexus IS350 come from 2 brands — AGILITY and UAC.
Listed part numbers: AGILITY 6010036 and UAC FA50658C.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814519 | 🇺🇸 US 🇨🇦 CA | Connector Gender: Female | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| STANDARD MOTOR PRODUCTS | TX273 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| WELLS | 5S15288 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207157 | 🇺🇸 US 🇨🇦 CA | F Sport or F Sport Design | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
4 Temperature Sender / Sensor parts are listed for the 2024 Lexus IS350, from GPD, STANDARD MOTOR PRODUCTS, WELLS and 1 other brand.
Economy: 1 part, from GPD. A representative part number is GPD 1814519.
The Standard Replacement section: 2 options from STANDARD MOTOR PRODUCTS and WELLS. STANDARD MOTOR PRODUCTS TX273 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
This group includes GPD 1814519, STANDARD MOTOR PRODUCTS TX273 and WELLS 5S15288 and the remaining parts above.
Buying Cooling System Parts for a 2024 Lexus IS350
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.5L V6 engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Temperature Sender / Sensor .
Frequently Asked Questions
How many cooling system parts fit the 2024 Lexus IS350?
Our catalog currently lists 28 cooling system parts for the 2024 Lexus IS350 across 6 subcategories and 17 brands, covering the 3.5L V6 engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2024 Lexus IS350?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2024 Lexus IS350 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2024 Lexus IS350?
Every part on this page is matched to the 3.5L V6 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2024 Lexus IS350
Cooling System Parts for Other Lexus IS350 Years
Switch vehicle or jump to a subcategory
Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.