26 Cooling system parts are listed for the 2025 Lexus LX600, in 6 part types, covering the 3.4L V6 Turbocharged engine. Each one has a brand, a manufacturer part number and notes that say where it fits.
The cooling system system on the 2025 Lexus LX600 keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (10 parts), Temperature Sender / Sensor (4 parts) and Water Pump (4 parts). The other 3 part types cover the remaining 8 parts.
Every part on this page is matched to the 3.4L V6 Turbocharged — the only engine offered in the 2025 Lexus LX600.
The most listed brands for 2025 Lexus LX600 cooling system parts are PRESTONE (6 parts), VALVOLINE (2 parts) and AISIN (2 parts), plus 13 more brands. Quality grades include Standard Replacement, Economy and Premium.
2 parts on this 2025 Lexus LX600 page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including PRESTONE AF2100 (Coolant / Antifreeze) and AISIN ACT002 (Coolant / Antifreeze). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AFC12100 | 🇺🇸 US 🇨🇦 CA | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA | PinkHOAT | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
10 Coolant / Antifreeze parts for the 2025 Lexus LX600 come from 4 brands — PRESTONE, VALVOLINE, AISIN and 1 other brand. The "Popular" part is PRESTONE AF2100.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 2 options from PRESTONE and VALVOLINE — the catalog's value-priced group. PRESTONE AF3100 is listed in this group.
In the Heavy Duty grade, PRESTONE supplies 1 part: rated for severe service. A representative part number is PRESTONE AFC12100.
In the Premium grade, PRESTONE supplies 3 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, AISIN, PENTOSIN and VALVOLINE supply 3 parts: built to original-equipment specification. A representative part number is AISIN ACT002.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0145 | 🇺🇸 US 🇨🇦 CA | Attachment Type: Threaded | View on Amazon |
| MOTORAD | T51 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
2 Coolant Reservoir Cap parts are listed for the 2025 Lexus LX600, from CALORSTAT and MOTORAD.
Part numbers include CALORSTAT RC0145 and MOTORAD T51.
Radiator Fan Clutch
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FOUR SEASONS | 46159 | 🇺🇸 US 🇨🇦 CA | Electronic | View on Amazon |
| HAYDEN | 3350 | 🇺🇸 US 🇨🇦 CA | Electronic | View on Amazon |
| US MOTOR WORKS | 22365 | 🇺🇸 US 🇨🇦 CA | F Sport Handling or Luxury or Premium | View on Amazon |
This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.
3 Radiator Fan Clutch parts for the 2025 Lexus LX600 come from 3 brands — FOUR SEASONS, HAYDEN and US MOTOR WORKS.
Listed part numbers: FOUR SEASONS 46159, HAYDEN 3350 and US MOTOR WORKS 22365.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814549 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| BECK/ARNLEY | 1581797 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| STANDARD MOTOR PRODUCTS | TX319 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207139 | 🇺🇸 US 🇨🇦 CA | F Sport Handling or Luxury or Premium | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
4 Temperature Sender / Sensor parts for the 2025 Lexus LX600 come from 4 brands — GPD, BECK/ARNLEY, STANDARD MOTOR PRODUCTS and 1 other brand.
The Economy section: 1 option from GPD. GPD 1814549 is listed in this group.
Standard Replacement: 2 parts, from BECK/ARNLEY and STANDARD MOTOR PRODUCTS. A representative part number is BECK/ARNLEY 1581797.
1 further part sits outside the graded sections, with the same engine-level match.
Part numbers include GPD 1814549, BECK/ARNLEY 1581797 and STANDARD MOTOR PRODUCTS TX319, among others listed above.
Thermostat
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN | THT027 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| JAPANESE OE | WHTYJ82 | 🇺🇸 US 🇨🇦 CA | TamaIncludes Seal | View on Amazon |
| MOTORAD | 1450180 | 🇺🇸 US 🇨🇦 CA | Assembly | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
3 Thermostat parts are listed for the 2025 Lexus LX600, from AISIN, JAPANESE OE and MOTORAD.
Listed part numbers: AISIN THT027, JAPANESE OE WHTYJ82 and MOTORAD 1450180.
Water Pump
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP | 1704230 | 🇺🇸 US 🇨🇦 CA | Water Pump Drive Type: Serpentine Belt | View on Amazon |
| FVP | US8239 | 🇺🇸 US 🇨🇦 CA | F Sport Handling or Luxury or Premium | View on Amazon |
| GMB | 1704230 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| US MOTOR WORKS | US8239 | 🇺🇸 US 🇨🇦 CA | F Sport Handling or Luxury or Premium | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
4 Water Pump parts are listed for the 2025 Lexus LX600, from FVP, GMB and US MOTOR WORKS.
Listed part numbers: FVP 1704230 and FVP US8239, plus the other parts above.
Buying Cooling System Parts for a 2025 Lexus LX600
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.4L V6 Turbocharged engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Temperature Sender / Sensor .
Frequently Asked Questions
How many cooling system parts fit the 2025 Lexus LX600?
Our catalog currently lists 26 cooling system parts for the 2025 Lexus LX600 across 6 subcategories and 16 brands, covering the 3.4L V6 Turbocharged engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2025 Lexus LX600?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus LX600 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2025 Lexus LX600?
Every part on this page is matched to the 3.4L V6 Turbocharged engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2025 Lexus LX600
Cooling System Parts for Other Lexus LX600 Years
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