2025 Lexus NX250 Cooling System Parts

Engine:
2.5L L4

43 Cooling system parts are listed for the 2025 Lexus NX250, in 9 part types, covering the 2.5L L4 engine. Each one has a brand, a manufacturer part number and notes that say where it fits.

On the 2025 Lexus NX250, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Coolant / Antifreeze (10 parts), Radiator Fan Assembly (8 parts) and Radiator (7 parts). The other 6 part types cover the remaining 18 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE AF3055
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
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Economy

Brand Part Number Markets Notes Buy
PRESTONE AF3100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
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VALVOLINE 719009
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Multi-Vehicle Yellow1 Gallon
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Heavy Duty

Brand Part Number Markets Notes Buy
PRESTONE AFC12100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT
Fitment notes — PRESTONE AFC12100
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT1 GAL Ready To Use 50/50
Heavy Duty & Mixed Fleet Nitrite Free Extended Life CoolantYellow Fluid Class 1 - 8
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular AF2100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
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PRESTONE AF6210
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
MAX Original EquipmentAsian Red/Pink
Fitment notes — PRESTONE AF6210
MAX Original EquipmentAsian Red/PinkReady To Use 1 Gallon
(Type: Prediluted)
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PRESTONE AFMAX
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular ACT002
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
PinkHOAT
Fitment notes — AISIN ACT002
PinkHOAT
(Type: Prediluted)
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PENTOSIN 8115209
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Pentofrost A41 Gallon
Fitment notes — PENTOSIN 8115209
Pentofrost A41 GallonPink
(Type: Prediluted)
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VALVOLINE 675130
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Asian Vehicle Red1 Gallon
Fitment notes — VALVOLINE 675130
Asian Vehicle Red1 GallonPOAT
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Reservoir

Brand Part Number Markets Notes Buy
TECHPRO TO3014141
🇺🇸 US 🇨🇦 CA
Includes Cap
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This table covers the overflow / expansion tanks that hold extra coolant.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
CALORSTAT RC0170
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Attachment Type: Push Fit
Fitment notes — CALORSTAT RC0170
Attachment Type: Push Fit
To 06/2025
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator

Economy

Brand Part Number Markets Notes Buy
TECHPRO TO3010364
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
North America Built Vehicle
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Standard Replacement

Brand Part Number Markets Notes Buy
CSF Popular 3858
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Upgraded with Higher Performance & Stronger B-Tube Design
Fitment notes — CSF 3858
Upgraded with Higher Performance & Stronger B-Tube Design
For vehicle built in Japan or North America Built
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TYC Popular 13670
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
North America Built
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NISSENS 606786
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Brazed cooling fins
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OSC 13670
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
For vehicle built in USA
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SPECTRA PREMIUM CU13670
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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UAC RA13670C
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
For vehicle built in USA or For vehicle built in Japanwith AWD
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Brand Part Number Markets Notes Buy
CALORSTAT RC0047
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Includes 2 sealsMetallic
Fitment notes — CALORSTAT RC0047
Includes 2 sealsMetallicDegassing function
PSI - 16.0
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GATES 31411
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
OE Type
Fitment notes — GATES 31411
OE Type
13 psi Pressure Rating
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MOTORAD T36
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Standard
Fitment notes — MOTORAD T36
Standard
Relief Pressure 13 lbs
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SKP SK10241
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Pressure Rating 13 psi
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Assembly

Economy

Brand Part Number Markets Notes Buy
TECHPRO TO3115202
🇺🇸 US
FWDNorth America Built Vehicle
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TECHPRO TO3115210
🇺🇸 US 🇨🇦 CA
AWDFor vehicle built in Japan
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Standard Replacement

Brand Part Number Markets Notes Buy
TYC Popular 624200
🇺🇸 US
FWD
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TYC Popular 624440
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Fits AWDFor vehicle built in Japanor AWD
Fitment notes — TYC 624440
Fits:
AWDFor vehicle built in Japanor AWDFor vehicle built in USA
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ACKOJA A70010012
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
AWDTo 06/2025
Fitment notes — ACKOJA A70010012
AWDTo 06/2025with OE No. 1636031500
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AGILITY 6010458
🇺🇸 US
FWDSingle Fan Replacement
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AGILITY 6010467
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
AWDFor vehicle built in Japan
Fitment notes — AGILITY 6010467
AWDFor vehicle built in JapanSingle Fan Replacement
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AGILITY 6010546
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Single Fan Configuration
Fitment notes — AGILITY 6010546
Single Fan Configuration
AWDUSA Built
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This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.

Radiator Hose

Brand Part Number Markets Notes Buy
GATES 52065
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Molded
Fitment notes — GATES 52065
Molded
LowerModels made in Canada.
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GATES 52435
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Molded
Fitment notes — GATES 52435
Molded
Fits:
UpperModels made In Canada
or:
UpperModels made In Japan
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This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
GPD 1814549
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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Standard Replacement

Brand Part Number Markets Notes Buy
STANDARD MOTOR PRODUCTS Popular TX319
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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WALKER PRODUCTS 2112017
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Sensor Only
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WELLS 5S17570
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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Brand Part Number Markets Notes Buy
NISSENS 207139
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Thermostat

Brand Part Number Markets Notes Buy
MOTORAD Popular 1115180
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Includes Housing, Gasket
Fitment notes — MOTORAD 1115180
Includes Housing, Gasket
180 Degrees FOE Specified Temperature
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ACKOJA A70990021
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
with HousingTo 08/2025
Fitment notes — ACKOJA A70990021
with HousingTo 08/2025with OE No. 1603125011
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AISIN THT023
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
82°C
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BECK/ARNLEY 1430982
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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FOUR SEASONS 86328
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Includes Housing
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This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.

Buying Cooling System Parts for a 2025 Lexus NX250

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Confirm you have the 2.5L L4 engine — every part on this page is matched to it.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Coolant / Antifreeze and Radiator Fan Assembly .

Frequently Asked Questions

How many cooling system parts fit the 2025 Lexus NX250?

Our catalog currently lists 43 cooling system parts for the 2025 Lexus NX250 across 9 subcategories and 23 brands, covering the 2.5L L4 engine. Each part is matched to the engine(s) it fits.

What are the signs of cooling system problems on a 2025 Lexus NX250?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus NX250 was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2025 Lexus NX250?

Every part on this page is matched to the 2.5L L4 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2025 Lexus NX250

Cooling System Parts for Other Lexus NX250 Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.