43 Cooling system parts are listed for the 2025 Lexus NX250, in 9 part types, covering the 2.5L L4 engine. Each one has a brand, a manufacturer part number and notes that say where it fits.
On the 2025 Lexus NX250, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Coolant / Antifreeze (10 parts), Radiator Fan Assembly (8 parts) and Radiator (7 parts). The other 6 part types cover the remaining 18 parts.
The 2025 Lexus NX250 came with a single engine, the 2.5L L4, and every part is verified against it.
23 brands supply cooling system parts for the 2025 Lexus NX250, led by PRESTONE (6 parts), TECHPRO (4 parts) and TYC (3 parts), plus 20 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2025 Lexus NX250. 8 parts have it, including PRESTONE AF2100 (Coolant / Antifreeze) and CSF 3858 (Radiator). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AFC12100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles10yr/300k mi | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | PinkHOAT | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 675130 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Asian Vehicle Red1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
10 Coolant / Antifreeze parts are listed for the 2025 Lexus NX250, from PRESTONE, VALVOLINE, AISIN and 1 other brand. PRESTONE AF2100 carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, PRESTONE and VALVOLINE supply 2 parts: the catalog's value-priced group. A representative part number is PRESTONE AF3100.
The Heavy Duty section lists 1 option from PRESTONE — rated for severe service. PRESTONE AFC12100 is listed in this group.
The Premium section lists 3 options from PRESTONE — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 3 options from AISIN, PENTOSIN and VALVOLINE — built to original-equipment specification. AISIN ACT002 is listed in this group.
Coolant Reservoir
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO | TO3014141 | 🇺🇸 US 🇨🇦 CA | Includes Cap | View on Amazon |
This table covers the overflow / expansion tanks that hold extra coolant.
This group shows a single part: TECHPRO TO3014141.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0170 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Attachment Type: Push Fit | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: CALORSTAT RC0170.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO | TO3010364 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | North America Built Vehicle | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF Popular | 3858 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Upgraded with Higher Performance & Stronger B-Tube Design | View on Amazon |
| TYC Popular | 13670 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | North America Built | View on Amazon |
| NISSENS | 606786 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Brazed cooling fins | View on Amazon |
| OSC | 13670 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | For vehicle built in USA | View on Amazon |
| SPECTRA PREMIUM | CU13670 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| UAC | RA13670C | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | For vehicle built in USA or For vehicle built in Japanwith AWD | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
7 Radiator parts are listed for the 2025 Lexus NX250, from TECHPRO, CSF, TYC and 4 other brands. CSF 3858 carries the "Popular" badge.
Economy: 1 part, from TECHPRO. A representative part number is TECHPRO TO3010364.
The Standard Replacement section: 6 options from CSF, TYC, NISSENS and 3 other brands. CSF 3858 is listed in this group.
Part numbers include CSF 3858, TECHPRO TO3010364 and TYC 13670, among others listed above.
Radiator Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0047 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Includes 2 sealsMetallic | View on Amazon |
| GATES | 31411 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | OE Type | View on Amazon |
| MOTORAD | T36 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Standard | View on Amazon |
| SKP | SK10241 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pressure Rating 13 psi | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
4 Radiator Cap parts are listed for the 2025 Lexus NX250, from CALORSTAT, GATES, MOTORAD and 1 other brand.
Part numbers include CALORSTAT RC0047, GATES 31411 and MOTORAD T36, among others listed above.
Radiator Fan Assembly
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO | TO3115202 | 🇺🇸 US | FWDNorth America Built Vehicle | View on Amazon |
| TECHPRO | TO3115210 | 🇺🇸 US 🇨🇦 CA | AWDFor vehicle built in Japan | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TYC Popular | 624200 | 🇺🇸 US | FWD | View on Amazon |
| TYC Popular | 624440 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Fits AWDFor vehicle built in Japanor AWD | View on Amazon |
| ACKOJA | A70010012 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | AWDTo 06/2025 | View on Amazon |
| AGILITY | 6010458 | 🇺🇸 US | FWDSingle Fan Replacement | View on Amazon |
| AGILITY | 6010467 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | AWDFor vehicle built in Japan | View on Amazon |
| AGILITY | 6010546 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Single Fan Configuration | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
8 Radiator Fan Assembly parts for the 2025 Lexus NX250 come from 4 brands — AGILITY, TECHPRO, TYC and 1 other brand. The "Popular" part is TYC 624200.
The Economy section: 2 options from TECHPRO. TECHPRO TO3115202 is listed in this group.
Standard Replacement: 6 parts, from AGILITY, TYC and ACKOJA. A representative part number is TYC 624200.
This group includes TYC 624200, TECHPRO TO3115202 and TECHPRO TO3115210 and the remaining parts above.
Radiator Hose
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES | 52065 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Molded | View on Amazon |
| GATES | 52435 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Molded | View on Amazon |
This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.
2 Radiator Hose parts for the 2025 Lexus NX250 come from GATES.
This group includes GATES 52065 and GATES 52435.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814549 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| STANDARD MOTOR PRODUCTS Popular | TX319 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| WALKER PRODUCTS | 2112017 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Sensor Only | View on Amazon |
| WELLS | 5S17570 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207139 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
5 Temperature Sender / Sensor parts are listed for the 2025 Lexus NX250, from GPD, STANDARD MOTOR PRODUCTS, WALKER PRODUCTS and 2 other brands. STANDARD MOTOR PRODUCTS TX319 carries the "Popular" badge.
Economy: 1 part, from GPD. A representative part number is GPD 1814549.
The Standard Replacement section: 3 options from STANDARD MOTOR PRODUCTS, WALKER PRODUCTS and WELLS. STANDARD MOTOR PRODUCTS TX319 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
Listed part numbers: STANDARD MOTOR PRODUCTS TX319, GPD 1814549 and WALKER PRODUCTS 2112017, plus the other parts above.
Thermostat
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Popular | 1115180 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Includes Housing, Gasket | View on Amazon |
| ACKOJA | A70990021 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | with HousingTo 08/2025 | View on Amazon |
| AISIN | THT023 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | 82°C | View on Amazon |
| BECK/ARNLEY | 1430982 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| FOUR SEASONS | 86328 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Includes Housing | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
5 Thermostat parts for the 2025 Lexus NX250 come from 5 brands — MOTORAD, ACKOJA, AISIN and 2 other brands. The "Popular" part is MOTORAD 1115180.
Part numbers include MOTORAD 1115180, ACKOJA A70990021 and AISIN THT023, among others listed above.
Buying Cooling System Parts for a 2025 Lexus NX250
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 2.5L L4 engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Radiator Fan Assembly .
Frequently Asked Questions
How many cooling system parts fit the 2025 Lexus NX250?
Our catalog currently lists 43 cooling system parts for the 2025 Lexus NX250 across 9 subcategories and 23 brands, covering the 2.5L L4 engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2025 Lexus NX250?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus NX250 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2025 Lexus NX250?
Every part on this page is matched to the 2.5L L4 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2025 Lexus NX250
Cooling System Parts for Other Lexus NX250 Years
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