This page lists 23 cooling system parts for the 2025 Lexus RC350, across 7 part types, covering the 3.5L V6 engine. Every part shows its brand, manufacturer part number and fitment notes.
The cooling system system on the 2025 Lexus RC350 keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (9 parts), Water Pump (5 parts) and Temperature Sender / Sensor (3 parts). The other 4 part types cover the remaining 6 parts.
The 2025 Lexus RC350 came with a single engine, the 3.5L V6, and every part is verified against it.
16 brands supply cooling system parts for the 2025 Lexus RC350, led by PRESTONE (5 parts), AISIN (3 parts) and VALVOLINE (2 parts), plus 13 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2025 Lexus RC350. 3 parts have it, including PRESTONE AF2100 (Coolant / Antifreeze) and AISIN WPT808 (Water Pump). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA | PinkHOAT | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
9 Coolant / Antifreeze parts are listed for the 2025 Lexus RC350, from PRESTONE, VALVOLINE, AISIN and 1 other brand. PRESTONE AF2100 carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, PRESTONE and VALVOLINE supply 2 parts: the catalog's value-priced group. A representative part number is PRESTONE AF3100.
The Premium section lists 3 options from PRESTONE — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 3 options from AISIN, PENTOSIN and VALVOLINE — built to original-equipment specification. AISIN ACT002 is listed in this group.
This group includes PRESTONE AF2100, PRESTONE AF3055 and PRESTONE AF3100 and the remaining parts above.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0145 | 🇺🇸 US 🇨🇦 CA | Attachment Type: Threaded | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: CALORSTAT RC0145.
Radiator
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 13570C | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
One part is listed for the 2025 Lexus RC350 — GPD 13570C.
Radiator Fan Assembly
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| UAC | FA50737C | 🇺🇸 US 🇨🇦 CA | Radiator-Condenser Fan Assembly | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
This group shows a single part: UAC FA50737C.
Temperature Sender / Sensor
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207157 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| STANDARD MOTOR PRODUCTS | TX273 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| WELLS | 5S15288 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
3 Temperature Sender / Sensor parts are listed for the 2025 Lexus RC350, from NISSENS, STANDARD MOTOR PRODUCTS and WELLS.
Listed part numbers: NISSENS 207157, STANDARD MOTOR PRODUCTS TX273 and WELLS 5S15288.
Thermostat
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN | THT029 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FOUR SEASONS | 86320 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
| MOTORAD | 1046188 | 🇺🇸 US 🇨🇦 CA | Includes Housing, Sensor, Seal | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
3 Thermostat parts for the 2025 Lexus RC350 come from 3 brands — AISIN, FOUR SEASONS and MOTORAD.
Listed part numbers: AISIN THT029, FOUR SEASONS 86320 and MOTORAD 1046188.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP | US8150 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| US MOTOR WORKS | US8150 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | WPT808 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DAYCO | DP2182 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB | 1703020 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
5 Water Pump parts for the 2025 Lexus RC350 come from 5 brands — FVP, US MOTOR WORKS, AISIN and 2 other brands. The "Popular" part is AISIN WPT808.
The Economy section: 2 options from FVP and US MOTOR WORKS. FVP US8150 is listed in this group.
Standard Replacement: 3 parts, from AISIN, DAYCO and GMB. A representative part number is AISIN WPT808.
Listed part numbers: AISIN WPT808 and FVP US8150, plus the other parts above.
Buying Cooling System Parts for a 2025 Lexus RC350
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.5L V6 engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2025 Lexus RC350?
Our catalog currently lists 23 cooling system parts for the 2025 Lexus RC350 across 7 subcategories and 16 brands, covering the 3.5L V6 engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2025 Lexus RC350?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus RC350 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2025 Lexus RC350?
Every part on this page is matched to the 3.5L V6 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2025 Lexus RC350
Cooling System Parts for Other Lexus RC350 Years
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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.