2025 Lexus RX500H Cooling System Parts

Engine:
2.4L L4 ELECTRIC/GAS Turbocharged

30 Cooling system parts are listed for the 2025 Lexus RX500H, in 7 part types, covering the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Each one has a brand, a manufacturer part number and notes that say where it fits.

On the 2025 Lexus RX500H, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 22 parts of the 30 listed are Coolant / Antifreeze (10 parts), Temperature Sender / Sensor (7 parts) and Radiator (5 parts). The other 4 part types cover the remaining 8 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE AF3055
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
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Economy

Brand Part Number Markets Notes Buy
PRESTONE AF3100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
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Heavy Duty

Brand Part Number Markets Notes Buy
PRESTONE AFC12100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT
Fitment notes — PRESTONE AFC12100
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT1 GAL Ready To Use 50/50
Heavy Duty & Mixed Fleet Nitrite Free Extended Life CoolantYellow Fluid Class 1 - 8
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular AF2100
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
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PRESTONE AF6210
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
MAX Original EquipmentAsian Red/Pink
Fitment notes — PRESTONE AF6210
MAX Original EquipmentAsian Red/PinkReady To Use 1 Gallon
(Type: Prediluted)
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PRESTONE AFMAX
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular ACT002
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
PinkHOAT
Fitment notes — AISIN ACT002
PinkHOAT
(Type: Prediluted)
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PENTOSIN 8115209
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Pentofrost A41 Gallon
Fitment notes — PENTOSIN 8115209
Pentofrost A41 GallonPink
(Type: Prediluted)
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VALVOLINE 675130
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Asian Vehicle Red1 Gallon
Fitment notes — VALVOLINE 675130
Asian Vehicle Red1 GallonPOAT
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VALVOLINE 898406
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Hybrid Vehicle1 Gallon
Fitment notes — VALVOLINE 898406
Hybrid Vehicle1 Gallon
(Type: Prediluted)
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
CALORSTAT RC0170
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Attachment Type: Push Fit
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CALORSTAT RC0145
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Attachment Type: Threaded
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MOTORAD T51
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Standard
Fitment notes — MOTORAD T51
Standard
Relief Pressure 16 lbsInverter Cooling System
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator

Economy

Brand Part Number Markets Notes Buy
GPD 13913C
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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TECHPRO LX3010164
🇺🇸 US 🇨🇦 CA
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Standard Replacement

Brand Part Number Markets Notes Buy
CSF Popular 3954
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Upgraded Core. 11% Thicker 30mm vs OEM 27mm
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TYC 13984
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
F Sport or F Sport Performance
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Brand Part Number Markets Notes Buy
FVP RAD14046
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Secondary
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Brand Part Number Markets Notes Buy
CALORSTAT RC0047
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Includes 2 sealsMetallic
Fitment notes — CALORSTAT RC0047
Includes 2 sealsMetallicDegassing function
PSI - 16.0
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MOTORAD T36
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Standard
Fitment notes — MOTORAD T36
Standard
Relief Pressure 13 lbsEngine # Cooling
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Assembly

Brand Part Number Markets Notes Buy
TYC 625010
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
GPD 1814549
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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HOLSTEIN 2CTS0051
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Located on Thermostat Housing
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Standard Replacement

Brand Part Number Markets Notes Buy
ACDELCO Popular D583
🇺🇸 US 🇨🇦 CA
Gold
Fitment notes — ACDELCO D583
Gold
Located on Thermostat Housing
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STANDARD MOTOR PRODUCTS Popular TX40
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Rectangular Connector2 Terminal
Fitment notes — STANDARD MOTOR PRODUCTS TX40
Rectangular Connector2 Terminal
Located on Thermostat Housing
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STANDARD MOTOR PRODUCTS TX273
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Engine BlockOn Side of Block
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WELLS 5S1616
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Connector Shape: Rectangular
Fitment notes — WELLS 5S1616
Connector Shape: Rectangular
In Engine
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WELLS 5S17570
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
Located in Radiator
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Water Pump

Brand Part Number Markets Notes Buy
FVP 1704220
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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GMB 1704220
🇺🇸 US 🇨🇦 CA 🇲🇽 MX
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This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.

Buying Cooling System Parts for a 2025 Lexus RX500H

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Confirm you have the 2.4L L4 ELECTRIC/GAS Turbocharged engine — every part on this page is matched to it.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Coolant / Antifreeze and Temperature Sender / Sensor .

Frequently Asked Questions

How many cooling system parts fit the 2025 Lexus RX500H?

Our catalog currently lists 30 cooling system parts for the 2025 Lexus RX500H across 7 subcategories and 16 brands, covering the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Each part is matched to the engine(s) it fits.

What are the signs of cooling system problems on a 2025 Lexus RX500H?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus RX500H was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2025 Lexus RX500H?

Every part on this page is matched to the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2025 Lexus RX500H

Cooling System Parts for Other Lexus RX500H Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.