2025 Lexus TX350 Cooling System Parts

This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator. Read more

11 Coolant / Antifreeze parts for the 2025 Lexus TX350 come from 5 brands — PRESTONE, VALVOLINE, AISIN and 2 other brands. The "Popular" part is PRESTONE AF2100.

In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.

The Economy section lists 2 options from PRESTONE and VALVOLINE — the catalog's value-priced group. PRESTONE AF3100 is listed in this group.

In the Heavy Duty grade, PRESTONE supplies 1 part: rated for severe service. A representative part number is PRESTONE AFC12100.

In the Premium grade, PRESTONE supplies 3 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.

In the Standard Replacement grade, AISIN, VALVOLINE, BECK/ARNLEY and 1 other brand supply 4 parts: built to original-equipment specification. A representative part number is AISIN ACT002.

This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable. Read more

3 Coolant Reservoir Cap parts are listed for the 2025 Lexus TX350, from CALORSTAT, GATES and MOTORAD.

Listed part numbers: CALORSTAT RC0145, GATES 31541 and MOTORAD T51.

This table covers the Inverter coolers. Typical signs include overheated fluid, a leak at the fittings, or mixed fluids in the reservoir. Flush the lines when you replace a cooler. Read more

One part is listed for the 2025 Lexus TX350 — GPD 14045C.

This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap. Read more

5 Radiator parts for the 2025 Lexus TX350 come from 4 brands — CSF, GPD, KOYORAD and 1 other brand. The "Popular" part is CSF 4016.

The Economy section: 1 option from GPD. GPD 14007C is listed in this group.

Standard Replacement: 3 parts, from CSF and KOYORAD. A representative part number is CSF 4016.

1 further part sits outside the graded sections, with the same engine-level match.

Part numbers include CSF 4016, GPD 14007C and CSF 4017, among others listed above.

This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable. Read more

2 Radiator Cap parts for the 2025 Lexus TX350 come from 2 brands — CALORSTAT and GATES.

Listed part numbers: CALORSTAT RC0047 and GATES 31411.

This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator. Read more

3 Radiator Fan Assembly parts are listed for the 2025 Lexus TX350, from GPD, TECHPRO and TYC.

Economy: 2 parts, from GPD and TECHPRO. A representative part number is GPD 2812473.

The Standard Replacement section: 1 option from TYC. TYC 625620 is listed in this group.

Part numbers include GPD 2812473, TECHPRO TO3115229 and TYC 625620.

This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender. Read more

7 Temperature Sender / Sensor parts for the 2025 Lexus TX350 come from 5 brands — STANDARD MOTOR PRODUCTS, WELLS, GPD and 2 other brands. The "Popular" part is ACDELCO D583.

The Economy section: 2 options from GPD and HOLSTEIN. GPD 1814549 is listed in this group.

Standard Replacement: 5 parts, from STANDARD MOTOR PRODUCTS, WELLS and ACDELCO. A representative part number is ACDELCO D583.

This group includes ACDELCO D583, GPD 1814549 and HOLSTEIN 2CTS0051 and the remaining parts above.

This table covers the housings and outlets the thermostat sits in. Read more

One part is listed for the 2025 Lexus TX350 — MOTORAD CH2175.

This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off. Read more

8 Water Pump parts are listed for the 2025 Lexus TX350, from FVP, AISIN, GATES and 4 other brands. AISIN WPT211 carries the "Popular" badge.

Listed part numbers: AISIN WPT211, GATES 41564E and FOUR SEASONS 89072, plus the other parts above.