The 2025 Lexus TX550H+ has 32 cooling system parts with verified fitment on this page — 7 part types and 18 brands, covering the 3.5L V6 ELECTRIC/GAS engine. Each part includes a manufacturer part number and application notes.
On the 2025 Lexus TX550H+, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. Most of the listed parts are Coolant / Antifreeze (11 parts), Water Pump (6 parts) and Radiator (4 parts). The other 4 part types cover the remaining 11 parts.
The 2025 Lexus TX550H+ came with a single engine, the 3.5L V6 ELECTRIC/GAS, and every part is verified against it.
18 brands supply cooling system parts for the 2025 Lexus TX550H+, led by PRESTONE (6 parts), AISIN (3 parts) and MOTORAD (3 parts), plus 15 more brands. Quality grades include Standard Replacement, Economy and Premium.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2025 Lexus TX550H+. 5 parts have it, including PRESTONE AF2100 (Coolant / Antifreeze) and US MOTOR WORKS US8150 (Water Pump). Each part number opens a page with every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3100 | 🇺🇸 US | Prime Yellow - All VehiclesExtended Life | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AFC12100 | 🇺🇸 US | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US | All Vehicles10yr/300k mi | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US | PinkHOAT | View on Amazon |
| VALVOLINE Popular | 675130 | 🇺🇸 US | Asian Vehicle Red1 Gallon | View on Amazon |
| BECK/ARNLEY | 2521502 | 🇺🇸 US | Premium Extra Life Pink | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 898406 | 🇺🇸 US | Hybrid Vehicle1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
11 Coolant / Antifreeze parts are listed for the 2025 Lexus TX550H+, from PRESTONE, VALVOLINE, AISIN and 2 other brands. PRESTONE AF2100 carries the "Popular" badge.
The Compatible With All Colors section lists 1 option from PRESTONE — grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. PRESTONE AF3055 is listed in this group.
In the Economy grade, PRESTONE supplies 1 part: the catalog's value-priced group. A representative part number is PRESTONE AF3100.
The Heavy Duty section lists 1 option from PRESTONE — rated for severe service. PRESTONE AFC12100 is listed in this group.
The Premium section lists 3 options from PRESTONE — a step above OE specification in materials, tolerances or warranty terms. PRESTONE AF2100 is listed in this group.
The Standard Replacement section lists 5 options from VALVOLINE, AISIN, BECK/ARNLEY and 1 other brand — built to original-equipment specification. AISIN ACT002 is listed in this group.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0145 | 🇺🇸 US | Attachment Type: Threaded | View on Amazon |
| MOTORAD | T51 | 🇺🇸 US | Standard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
2 Coolant Reservoir Cap parts for the 2025 Lexus TX550H+ come from 2 brands — CALORSTAT and MOTORAD.
Listed part numbers: CALORSTAT RC0145 and MOTORAD T51.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 14007C | 🇺🇸 US | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF | 4016 | 🇺🇸 US | 11% Thicker Core 30mm vs OEM 27mm | View on Amazon |
| KOYORAD | A14007 | 🇺🇸 US | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP | RAD14046 | 🇺🇸 US | Secondary | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
4 Radiator parts are listed for the 2025 Lexus TX550H+, from GPD, CSF, KOYORAD and 1 other brand.
Economy: 1 part, from GPD. A representative part number is GPD 14007C.
The Standard Replacement section: 2 options from CSF and KOYORAD. CSF 4016 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
Listed part numbers: GPD 14007C, CSF 4016 and KOYORAD A14007, plus the other parts above.
Radiator Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | RC0047 | 🇺🇸 US | Includes 2 sealsMetallic | View on Amazon |
| MOTORAD | T36 | 🇺🇸 US | Standard | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
2 Radiator Cap parts are listed for the 2025 Lexus TX550H+, from CALORSTAT and MOTORAD.
Part numbers include CALORSTAT RC0047 and MOTORAD T36.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814549 | 🇺🇸 US | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| WELLS | 5S15288 | 🇺🇸 US | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207157 | 🇺🇸 US | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
3 Temperature Sender / Sensor parts are listed for the 2025 Lexus TX550H+, from GPD, WELLS and NISSENS.
Economy: 1 part, from GPD. A representative part number is GPD 1814549.
The Standard Replacement section: 1 option from WELLS. WELLS 5S15288 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
This group includes GPD 1814549, WELLS 5S15288 and NISSENS 207157.
Thermostat
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN | 9025212 | 🇺🇸 US | Includes Housing | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN | THT021 | 🇺🇸 US | 82°C | View on Amazon |
| FOUR SEASONS | 86321 | 🇺🇸 US | Includes Housing | View on Amazon |
| MOTORAD | 1040180 | 🇺🇸 US | Includes Housing, Seal | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
4 Thermostat parts for the 2025 Lexus TX550H+ come from 4 brands — DORMAN, AISIN, FOUR SEASONS and 1 other brand.
The Economy section: 1 option from DORMAN. DORMAN 9025212 is listed in this group.
Standard Replacement: 3 parts, from AISIN, FOUR SEASONS and MOTORAD. A representative part number is AISIN THT021.
Part numbers include DORMAN 9025212, AISIN THT021 and FOUR SEASONS 86321, among others listed above.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| US MOTOR WORKS Popular | US8150 | 🇺🇸 US | View on Amazon | |
| BECK/ARNLEY | 1312538 | 🇺🇸 US | View on Amazon | |
| FVP | US8150 | 🇺🇸 US | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | WPT808 | 🇺🇸 US | View on Amazon | |
| DAYCO | DP2182 | 🇺🇸 US | View on Amazon | |
| GMB | 1703020 | 🇺🇸 US | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
6 Water Pump parts for the 2025 Lexus TX550H+ come from 6 brands — US MOTOR WORKS, BECK/ARNLEY, FVP and 3 other brands. The "Popular" part is US MOTOR WORKS US8150.
The Economy section: 3 options from US MOTOR WORKS, BECK/ARNLEY and FVP. US MOTOR WORKS US8150 is listed in this group.
Standard Replacement: 3 parts, from AISIN, DAYCO and GMB. A representative part number is AISIN WPT808.
Listed part numbers: US MOTOR WORKS US8150 and BECK/ARNLEY 1312538, plus the other parts above.
Buying Cooling System Parts for a 2025 Lexus TX550H+
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.5L V6 ELECTRIC/GAS engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2025 Lexus TX550H+?
Our catalog currently lists 32 cooling system parts for the 2025 Lexus TX550H+ across 7 subcategories and 18 brands, covering the 3.5L V6 ELECTRIC/GAS engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2025 Lexus TX550H+?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2025 Lexus TX550H+ was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2025 Lexus TX550H+?
Every part on this page is matched to the 3.5L V6 ELECTRIC/GAS engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2025 Lexus TX550H+
Cooling System Parts for Other Lexus TX550H+ Years
Switch vehicle or jump to a subcategory
Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.