This page lists 16 cooling system parts for the 2026 Lexus TX500H, across 6 part types, covering the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Every part shows its brand, manufacturer part number and fitment notes.
The cooling system system on the 2026 Lexus TX500H keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (10 parts), Temperature Sender / Sensor (2 parts) and Inverter Cooler (1 part). The other 3 part types cover the remaining 3 parts.
Every part on this page is matched to the 2.4L L4 ELECTRIC/GAS Turbocharged — the only engine offered in the 2026 Lexus TX500H.
The most listed brands for 2026 Lexus TX500H cooling system parts are PRESTONE (6 parts), VALVOLINE (2 parts) and NISSENS (2 parts), plus 6 more brands. Quality grades include Standard Replacement, Premium and Compatible With All Colors.
2 parts on this 2026 Lexus TX500H page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including PRESTONE AF2100 (Coolant / Antifreeze) and AISIN ACT002 (Coolant / Antifreeze). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime Yellow - All VehiclesExtended Life | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AFC12100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles10yr/300k mi | View on Amazon |
| PRESTONE | AF6210 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular | ACT002 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | PinkHOAT | View on Amazon |
| PENTOSIN | 8115209 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost A41 Gallon | View on Amazon |
| VALVOLINE | 675130 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Asian Vehicle Red1 Gallon | View on Amazon |
| VALVOLINE | 898406 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Hybrid Vehicle1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
10 Coolant / Antifreeze parts for the 2026 Lexus TX500H come from 4 brands — PRESTONE, VALVOLINE, AISIN and 1 other brand. The "Popular" part is PRESTONE AF2100.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 1 option from PRESTONE — the catalog's value-priced group. PRESTONE AF3100 is listed in this group.
In the Heavy Duty grade, PRESTONE supplies 1 part: rated for severe service. A representative part number is PRESTONE AFC12100.
In the Premium grade, PRESTONE supplies 3 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, VALVOLINE, AISIN and PENTOSIN supply 4 parts: built to original-equipment specification. A representative part number is AISIN ACT002.
Inverter Cooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 14045C | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the Inverter coolers. Typical signs include overheated fluid, a leak at the fittings, or mixed fluids in the reservoir. Flush the lines when you replace a cooler.
One part is listed for the 2026 Lexus TX500H — GPD 14045C.
Radiator
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CSF | 4017 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Upgraded weld tube To B-fold tube | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
This group shows a single part: CSF 4017.
Radiator Fan Assembly
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TYC | 625620 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
One part is listed for the 2026 Lexus TX500H — TYC 625620.
Temperature Sender / Sensor
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| NISSENS | 207098 | 🇺🇸 US | F Sport Performance PremiumLocation-Thermostat Housing | View on Amazon |
| NISSENS | 207139 | 🇺🇸 US | F Sport Performance PremiumLocation-Control Valve | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
2 Temperature Sender / Sensor parts for the 2026 Lexus TX500H come from NISSENS.
Listed part numbers: NISSENS 207098 and NISSENS 207139.
Water Pump
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GMB | 1704220 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
One part is listed for the 2026 Lexus TX500H — GMB 1704220.
Buying Cooling System Parts for a 2026 Lexus TX500H
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 2.4L L4 ELECTRIC/GAS Turbocharged engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Temperature Sender / Sensor .
Frequently Asked Questions
How many cooling system parts fit the 2026 Lexus TX500H?
Our catalog currently lists 16 cooling system parts for the 2026 Lexus TX500H across 6 subcategories and 9 brands, covering the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2026 Lexus TX500H?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2026 Lexus TX500H was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2026 Lexus TX500H?
Every part on this page is matched to the 2.4L L4 ELECTRIC/GAS Turbocharged engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2026 Lexus TX500H
Cooling System Parts for Other Lexus TX500H Years
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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.