2021 Nissan Pathfinder Cooling System Parts

Engine:
3.5L V6

The 2021 Nissan Pathfinder has 41 cooling system parts with verified fitment on this page — 15 part types and 20 brands, covering the 3.5L V6 engine. Each part includes a manufacturer part number and application notes.

The cooling system system on the 2021 Nissan Pathfinder keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (12 parts), Thermostat (5 parts) and Radiator Fan Assembly (3 parts). The other 12 part types cover the remaining 21 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE AF3055
🇲🇽 MX
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
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Economy

Brand Part Number Markets Notes Buy
PRESTONE Popular AF3100
🇲🇽 MX
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
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PEAK BQA1GAL
🇲🇽 MX
Blue Mountain Long LifeAll Vehicle
Fitment notes — PEAK BQA1GAL
Blue Mountain Long LifeAll Vehicle1 Gallon
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VALVOLINE 719009
🇲🇽 MX
Multi-Vehicle Yellow1 Gallon
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Heavy Duty

Brand Part Number Markets Notes Buy
PRESTONE AFC12100
🇲🇽 MX
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT
Fitment notes — PRESTONE AFC12100
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT1 GAL Ready To Use 50/50
Heavy Duty & Mixed Fleet Nitrite Free Extended Life CoolantYellow Fluid Class 1 - 8
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular AF2100
🇲🇽 MX
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
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PEAK PKP1GAL
🇲🇽 MX
All Vehicles Antifreeze1 Gallon
Fitment notes — PEAK PKP1GAL
All Vehicles Antifreeze1 GallonPREMIUM1 GALLON10X MORE SCALE FIGHTING INHIBITORS10 YEAR/300K MILES
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PEAK PXA1GAL
🇲🇽 MX
Global Lifetime1 Gallon
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PRESTONE AFMAX
🇲🇽 MX
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN Popular ACB003
🇲🇽 MX
BlueHOAT
Fitment notes — AISIN ACB003
BlueHOAT
(Type: Prediluted)
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PEAK PAB1GAL
🇲🇽 MX
OET Asian Extended Life Blue1 Gallon
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PENTOSIN 8115207
🇲🇽 MX
Pentofrost A31 Gallon
Fitment notes — PENTOSIN 8115207
Pentofrost A31 GallonBluePOAT
(Type: Prediluted)
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Hose / Pipe Seal

Brand Part Number Markets Notes Buy
MAHLE / CLEVITE GS34113
🇲🇽 MX
Engine Coolant Outlet O-RingMolded Rubber
Fitment notes — MAHLE / CLEVITE GS34113
Engine Coolant Outlet O-RingMolded Rubber
Coolant Pipe O-Ring SetCoolant Pipe
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This table covers the seals at the Coolant Hose / Pipe. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Coolant Pipe Gasket

Brand Part Number Markets Notes Buy
FEL-PRO 35942
🇲🇽 MX
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This table covers the gaskets that seal the Coolant Pipe. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
DORMAN 54245
🇲🇽 MX
Black
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MOTORAD T152
🇲🇽 MX
Standard
Fitment notes — MOTORAD T152
Standard
Cap Only
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Cooling Fan Control Module

Brand Part Number Markets Notes Buy
DORMAN 921289
🇲🇽 MX
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SKP SK820025
🇲🇽 MX
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This table covers the Cooling Fan control modules.

Cooling System Tester Adapter

Brand Part Number Markets Notes Buy
MOTORAD 3121
🇲🇽 MX
StandardRadiator Cap Adapter
Fitment notes — MOTORAD 3121
StandardRadiator Cap Adapter
Cooling System PressureRadiator Cap Adapter
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This table covers the adapters used to pressure-test this cooling system.

Radiator

Brand Part Number Markets Notes Buy
CSF 3680
🇲🇽 MX
1 Row11% Thicker Core 30mm vs OEM 27mm
Fitment notes — CSF 3680
1 Row11% Thicker Core 30mm vs OEM 27mmPlastic Tank / Aluminum Core
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SPECTRA PREMIUM CU13348
🇲🇽 MX
Main Unit
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Brand Part Number Markets Notes Buy
DORMAN 54237
🇲🇽 MX
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MOTORAD T18R
🇲🇽 MX
Standard
Fitment notes — MOTORAD T18R
Standard
Relief Pressure 18 lbs
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Assembly

Economy

Brand Part Number Markets Notes Buy
DORMAN 621586
🇲🇽 MX
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Standard Replacement

Brand Part Number Markets Notes Buy
AGILITY 6010299
🇲🇽 MX
View on
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FOUR SEASONS 76333
🇲🇽 MX
View on
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This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
GPD 1712547
🇲🇽 MX
Engine Blockwith 2 Terminal(s)
Fitment notes — GPD 1712547
Engine Blockwith 2 Terminal(s)with M12 x 1.5 Thread
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HOLSTEIN 2CTS0057
🇲🇽 MX
Radiator Coolant Hose (Lower)
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Standard Replacement

Brand Part Number Markets Notes Buy
STANDARD MOTOR PRODUCTS TX186
🇲🇽 MX
Gray
Fitment notes — STANDARD MOTOR PRODUCTS TX186
Gray
Located on Radiator Hose
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Thermostat

Economy

Brand Part Number Markets Notes Buy
DORMAN Popular 9025902
🇲🇽 MX
Includes Housing
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SKP SK9025902
🇲🇽 MX
Includes Housing
Fitment notes — SKP SK9025902
Includes Housing
Cover
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Standard Replacement

Brand Part Number Markets Notes Buy
AISIN THN021
🇲🇽 MX
82°C
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FOUR SEASONS 86000
🇲🇽 MX
Includes Housing
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MOTORAD 1016180
🇲🇽 MX
Includes Housing, Thermostat
Fitment notes — MOTORAD 1016180
Includes Housing, Thermostat
180 Degrees FOE Specified Temperature
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This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.

Thermostat / Thermostat Housing / Water Outlet Seal

Brand Part Number Markets Notes Buy
MAHLE / CLEVITE C31681
🇲🇽 MX
Rubber Coated Beaded Steel
Fitment notes — MAHLE / CLEVITE C31681
Rubber Coated Beaded Steel
Water inlet
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MAHLE / CLEVITE C31680
🇲🇽 MX
Rubber Coated Beaded Steel
Fitment notes — MAHLE / CLEVITE C31680
Rubber Coated Beaded Steel
Water Outlet To Block, Water Outlet To ManifoldWater Outlet Seal
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This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Water Inlet Gasket

Brand Part Number Markets Notes Buy
ELRING 576720
🇲🇽 MX
AdvanceBody code: R52
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MAHLE / CLEVITE C31874
🇲🇽 MX
Rubber Coated Beaded Steel
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This table covers the gaskets that seal the Water Inlet. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Water Pump

Brand Part Number Markets Notes Buy
FVP 1502570
🇲🇽 MX
View on
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GMB 1502570
🇲🇽 MX
View on
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This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.

Water Pump Gasket

Brand Part Number Markets Notes Buy
MAHLE / CLEVITE GS33404
🇲🇽 MX
Rubber
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This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Buying Cooling System Parts for a 2021 Nissan Pathfinder

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Confirm you have the 3.5L V6 engine — every part on this page is matched to it.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Coolant / Antifreeze and Thermostat .

Frequently Asked Questions

How many cooling system parts fit the 2021 Nissan Pathfinder?

Our catalog currently lists 41 cooling system parts for the 2021 Nissan Pathfinder across 15 subcategories and 20 brands, covering the 3.5L V6 engine. Each part is matched to the engine(s) it fits.

What are the signs of cooling system problems on a 2021 Nissan Pathfinder?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Nissan Pathfinder was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2021 Nissan Pathfinder?

Every part on this page is matched to the 3.5L V6 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2021 Nissan Pathfinder

Cooling System Parts for Other Nissan Pathfinder Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.