The 2021 Audi S5 has 58 cooling system parts with verified fitment on this page — 15 part types and 28 brands, covering the 3.0L V6 Turbocharged engine. Each part includes a manufacturer part number and application notes.
On the 2021 Audi S5, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 35 parts of the 58 listed are Coolant / Antifreeze (16 parts), Water Pump (11 parts) and Temperature Sender / Sensor (8 parts). The other 12 part types cover the remaining 23 parts.
Every part on this page is matched to the 3.0L V6 Turbocharged — the only engine offered in the 2021 Audi S5.
The most listed brands for 2021 Audi S5 cooling system parts are PRESTONE (5 parts), PEAK (4 parts) and GPD (4 parts), plus 25 more brands. Quality grades include Standard Replacement, Economy and Premium.
10 parts on this 2021 Audi S5 page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including FVP MV5050GAL (Coolant / Antifreeze) and UAC FA50946C (Radiator Fan Assembly). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE | AF3055 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Popular | MV5050GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Extended LifeAll Makes / All Models | View on Amazon |
| PRESTONE Popular | AF3100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE Popular | 719009 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Multi-Vehicle Yellow1 Gallon | View on Amazon |
| PEAK | BQA1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Blue Mountain Long LifeAll Vehicle | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular | AF2100 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles10yr/300k mi | View on Amazon |
| PEAK | PKP1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK | PXA1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | 1 GallonGlobal Lifetime | View on Amazon |
| PRESTONE | AF6510 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | MAX European Violet1 Gallon | View on Amazon |
| PRESTONE | AFMAX | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN | ACE010 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | VioletSi-OAT | View on Amazon |
| PEAK | PEV1GAL | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | OET European Extended Life Violet1 Gallon | View on Amazon |
| PENTOSIN | 8114306 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost E1 Gallon | View on Amazon |
| PENTOSIN | 8113106 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost E1.5 Liters | View on Amazon |
| PENTOSIN | 8113206 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Pentofrost E5 Liters | View on Amazon |
| VALVOLINE | 904683 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | HT-12 Pink1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
16 Coolant / Antifreeze parts for the 2021 Audi S5 come from 6 brands — PRESTONE, PEAK, PENTOSIN and 3 other brands. The "Popular" part is FVP MV5050GAL.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 4 options from FVP, PRESTONE, VALVOLINE and 1 other brand — the catalog's value-priced group. FVP MV5050GAL is listed in this group.
In the Premium grade, PRESTONE and PEAK supply 5 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, PENTOSIN, AISIN, PEAK and 1 other brand supply 6 parts: built to original-equipment specification. A representative part number is AISIN ACE010.
Coolant Hose Flange Plug
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ÜRO PARTS | 357121140 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Plug Kit with Plug and O-Ring | View on Amazon |
This table covers the Coolant Hose Flange plugs. Typical signs include a leak at the drain or glow-plug hole, or a plug that has rounded off. Replace the crush washer and torque to the spec in the notes.
This group shows a single part: ÜRO PARTS 357121140.
Coolant Reservoir
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | EPT0271 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | without CAP | View on Amazon |
| VAICO | V105349 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the overflow / expansion tanks that hold extra coolant.
2 Coolant Reservoir parts are listed for the 2021 Audi S5, from REIN and VAICO.
This group includes REIN EPT0271 and VAICO V105349.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD | T111 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Standard | View on Amazon |
| ÜRO PARTS | 4M0121321Q | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
2 Coolant Reservoir Cap parts are listed for the 2021 Audi S5, from MOTORAD and ÜRO PARTS.
Listed part numbers: MOTORAD T111 and ÜRO PARTS 4M0121321Q.
Intercooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 2711414 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| TECHPRO | AU3012113 | 🇺🇸 US 🇨🇦 CA | Sportback | View on Amazon |
| TYC | 18105 | 🇺🇸 US | View on Amazon |
This table covers the intercoolers that cool turbo or supercharger charge air.
3 Intercooler parts for the 2021 Audi S5 come from 3 brands — GPD, TECHPRO and TYC.
This group includes GPD 2711414, TECHPRO AU3012113 and TYC 18105.
Radiator
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MAHLE / CLEVITE | CR960000S | 🇺🇸 US | Brazed cooling fins | View on Amazon |
| NISSENS | 606578 | 🇺🇸 US 🇲🇽 MX | Brazed cooling fins | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
2 Radiator parts for the 2021 Audi S5 come from 2 brands — MAHLE / CLEVITE and NISSENS.
Listed part numbers: MAHLE / CLEVITE CR960000S and NISSENS 606578.
Radiator Fan Assembly
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 2812266 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon | |
| VEMO | V15011943 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Fits RightConvertible | View on Amazon |
| VEMO | V15011942 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Fits LeftConvertible or Hatchback | View on Amazon |
| VEMO | V15011946 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| UAC Popular | FA50946C | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
5 Radiator Fan Assembly parts are listed for the 2021 Audi S5, from VEMO, GPD and UAC. UAC FA50946C carries the "Popular" badge.
Economy: 4 parts, from VEMO and GPD. A representative part number is GPD 2812266.
The Standard Replacement section: 1 option from UAC. UAC FA50946C is listed in this group.
Part numbers include UAC FA50946C, GPD 2812266 and VEMO V15011943, among others listed above.
Radiator Fan Shroud
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SKP | SK621318 | 🇺🇸 US | View on Amazon |
This table covers the shrouds that duct air through the fan and radiator.
This group shows a single part: SKP SK621318.
Radiator Insulator
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| VNE | 41000073 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Upper | View on Amazon |
| VNE | 41000074 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Lower | View on Amazon |
This table covers the Radiator insulators.
VNE supplies both parts for the 2021 Audi S5.
Listed part numbers: VNE 41000073 and VNE 41000074.
Radiator Insulator Sleeve
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | AVM0730 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | View on Amazon |
This table covers the Radiator Insulator sleeves.
One part is listed for the 2021 Audi S5 — REIN AVM0730.
Radiator Mount
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | AVM0729 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Center Upper | View on Amazon |
This table covers the Radiator mounts. Typical signs include a clunk on takeoff, a vibration at idle, or a separated rubber insert. Support the powertrain before unbolting a mount, and torque the fasteners in the notes.
One part is listed for the 2021 Audi S5 — REIN AVM0729.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD | 1814521 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Straight Connector | View on Amazon |
| GPD | 1816515 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | S5 Base ModelAngled Connector | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| BECK/ARNLEY Popular | 1581679 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | S5 Base Model | View on Amazon |
| WALKER PRODUCTS Popular | 2112035 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Sensor Only | View on Amazon |
| NISSENS | 207067 | 🇺🇸 US | Oval Connector, bolted connection | View on Amazon |
| STANDARD MOTOR PRODUCTS | TX355 | 🇺🇸 US 🇨🇦 CA | Convertible | View on Amazon |
| VNE | 9408050 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Lower | View on Amazon |
| WELLS | 5S16784 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Lower | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
8 Temperature Sender / Sensor parts for the 2021 Audi S5 come from 7 brands — GPD, BECK/ARNLEY, WALKER PRODUCTS and 4 other brands. The "Popular" part is BECK/ARNLEY 1581679.
The Economy section: 2 options from GPD. GPD 1814521 is listed in this group.
Standard Replacement: 6 parts, from BECK/ARNLEY, WALKER PRODUCTS, NISSENS and 3 other brands. A representative part number is BECK/ARNLEY 1581679.
Listed part numbers: BECK/ARNLEY 1581679, GPD 1814521 and GPD 1816515, plus the other parts above.
Thermostat
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT | TE7367103J | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Includes 1 Rubber Gasket | View on Amazon |
| MOTORAD | 1229221 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Includes Sensor and SealStandard | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
2 Thermostat parts are listed for the 2021 Audi S5, from CALORSTAT and MOTORAD.
This group includes CALORSTAT TE7367103J and MOTORAD 1229221.
Thermostat Housing / Water Outlet
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| VEMO | V10990020 | 🇺🇸 US | Thermostat Housing | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
One part is listed for the 2021 Audi S5 — VEMO V10990020.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| BECK/ARNLEY Popular | 1312513 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Auxiliary | View on Amazon |
| VAICO | V1050112 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | From 08/31/2017 | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GATES Popular | 41568E | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Electric | View on Amazon |
| FOUR SEASONS | 89087 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Auxiliary | View on Amazon |
| FOUR SEASONS | 89085 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | AuxiliaryHeater Water Pump | View on Amazon |
| FOUR SEASONS | 89084 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Turbocharger Coolant Pump | View on Amazon |
| NISSENS | 832121 | 🇺🇸 US | Auxiliary | View on Amazon |
| PIERBURG | 708002060 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Electric | View on Amazon |
| PIERBURG | 708002030 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Electric | View on Amazon |
| PIERBURG | 704071650 | 🇺🇸 US 🇨🇦 CA 🇲🇽 MX | Electric | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| HELLA Popular | 358304701 | 🇺🇸 US | Auxiliary | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
11 Water Pump parts are listed for the 2021 Audi S5, from FOUR SEASONS, PIERBURG, BECK/ARNLEY and 4 other brands. BECK/ARNLEY 1312513 carries the "Popular" badge.
Economy: 2 parts, from BECK/ARNLEY and VAICO. A representative part number is BECK/ARNLEY 1312513.
The Standard Replacement section: 8 options from FOUR SEASONS, PIERBURG, GATES and 1 other brand. GATES 41568E is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
Buying Cooling System Parts for a 2021 Audi S5
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Confirm you have the 3.0L V6 Turbocharged engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2021 Audi S5?
Our catalog currently lists 58 cooling system parts for the 2021 Audi S5 across 15 subcategories and 28 brands, covering the 3.0L V6 Turbocharged engine. Each part is matched to the engine(s) it fits.
What are the signs of cooling system problems on a 2021 Audi S5?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Audi S5 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2021 Audi S5?
Every part on this page is matched to the 3.0L V6 Turbocharged engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2021 Audi S5
Cooling System Parts for Other Audi S5 Years
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