The 2022 Ford E-450 has 3 drivetrain parts with verified fitment on this page — 2 part types and 3 brands, covering the 7.3L V8 engine. Each part includes a manufacturer part number and application notes.
On the 2022 Ford E-450, the drivetrain system moves power from transmission to wheels through axles, CV joints, driveshafts, differentials and wheel-end hardware. All 3 listed parts are Differential Pinion Seal (2 parts) and Axle Shaft Flange Gasket (1 part).
The 2022 Ford E-450 came with a single engine, the 7.3L V8, and every part is verified against it.
3 brands supply drivetrain parts for the 2022 Ford E-450, led by DORMAN (1 part), SCHAEFFLER (1 part) and TIMKEN (1 part).
Each part number listed for the 2022 Ford E-450 opens a page with every vehicle that part fits.
Axle Shaft Flange Gasket
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN | 926880 | 🇺🇸 US 🇨🇦 CA | Rear | View on Amazon |
This table covers the gaskets that seal the Axle Shaft Flange. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.
This group shows a single part: DORMAN 926880.
Differential Pinion Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SCHAEFFLER | SS2923 | 🇺🇸 US 🇨🇦 CA | Rear Outer3.21" O.D. X 0.5" Width | View on Amazon |
| TIMKEN | 100715V | 🇺🇸 US 🇨🇦 CA | Rear | View on Amazon |
This table covers the seals at the differential pinion yoke. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
2 Differential Pinion Seal parts are listed for the 2022 Ford E-450, from SCHAEFFLER and TIMKEN.
Listed part numbers: SCHAEFFLER SS2923 and TIMKEN 100715V.
Buying Drivetrain Parts for a 2022 Ford E-450
On this vehicle, the drivetrain system moves power from transmission to wheels through axles, CV joints, driveshafts, differentials and wheel-end hardware.
- Confirm you have the 7.3L V8 engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the differential or transfer-case fluid with any axle or seal job while everything is already open.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Differential Pinion Seal and Axle Shaft Flange Gasket .
Frequently Asked Questions
How many drivetrain parts fit the 2022 Ford E-450?
Our catalog currently lists 3 drivetrain parts for the 2022 Ford E-450 across 2 subcategories and 3 brands, covering the 7.3L V8 engine. Each part is matched to the engine(s) it fits.
What are the signs of drivetrain problems on a 2022 Ford E-450?
Common symptoms include clicking in tight turns, a clunk when shifting between drive and reverse, vibration that builds with speed, or gear oil on the inside of a wheel. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the differential or transfer-case fluid with any axle or seal job while everything is already open.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2022 Ford E-450 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2022 Ford E-450?
Every part on this page is matched to the 7.3L V8 engine. Then a torn CV boot caught early is a cheap boot kit; caught late it is a whole axle — inspect before deciding which to buy. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2022 Ford E-450
Drivetrain Parts for Other Ford E-450 Years
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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.