16 Engine parts are listed for the 2021 Freightliner Sprinter 4500, in 7 part types, covering the 3.0L V6 DIESEL Turbocharged engine. Each one has a brand, a manufacturer part number and notes that say where it fits.
On the 2021 Freightliner Sprinter 4500, the engine covers the internals and hard parts that build compression and keep oil where it belongs — gaskets, bearings, camshafts, lifters, seals and timing components. Most of the listed parts are Oil Filter (6 parts), Oil (5 parts) and Oil Cooler (1 part). The other 4 part types cover the remaining 4 parts.
The 2021 Freightliner Sprinter 4500 came with a single engine, the 3.0L V6 DIESEL Turbocharged, and every part is verified against it.
9 brands supply engine parts for the 2021 Freightliner Sprinter 4500, led by PENTOSIN (5 parts), REIN (4 parts) and FVP (1 part), plus 6 more brands. Quality grades include Economy and Standard Replacement.
A "Popular" badge means the source catalog flagged the part as frequently chosen for the 2021 Freightliner Sprinter 4500. 3 parts have it, including PENTOSIN 8042206 (Oil) and MANN HU821X (Oil Filter). Each part number opens a page with every vehicle that part fits.
Oil
Summary: Notes list SAE 5W-30 and SAE 5W-40. Confirm the weight on the filler cap before you buy. Replacement brands in this table include PENTOSIN.
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PENTOSIN Popular | 8042206 | 🇺🇸 US | High Performance IIFull Synthetic | View on Amazon |
| PENTOSIN | 8044218 | 🇺🇸 US | High PerformanceFull Synthetic | View on Amazon |
| PENTOSIN | 8042107 | 🇺🇸 US | High Performance IIFull Synthetic | View on Amazon |
| PENTOSIN | 8078106 | 🇺🇸 US | Super Performance IIIFull Synthetic | View on Amazon |
| PENTOSIN | 8078206 | 🇺🇸 US | Super Performance IIIFull Synthetic | View on Amazon |
This table covers the engine oils listed by grade and specification for this engine. Typical signs include a low-oil lamp, knocking after a long interval, or oil that has gone thin and black well before the next service. Match the viscosity and spec in the notes (and on the filler cap). The tables group grades — they are not interchangeable.
5 Oil parts for the 2021 Freightliner Sprinter 4500 come from PENTOSIN. The "Popular" part is PENTOSIN 8042206.
This group includes PENTOSIN 8042206, PENTOSIN 8044218 and PENTOSIN 8042107 and the remaining parts above.
Oil Cooler
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | ECK0026 | 🇺🇸 US | View on Amazon |
This table covers the heat exchangers that cool engine oil. Typical signs include oil at the cooler fittings, or coolant that looks like a milkshake. Pressure-test both circuits after a cooler swap — a leak here mixes oil and coolant.
This group shows a single part: REIN ECK0026.
Oil Cooler Mounting Kit
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | ECK0025 | 🇺🇸 US | View on Amazon |
This table covers the Oil Cooler Mounting kits.
One part is listed for the 2021 Freightliner Sprinter 4500 — REIN ECK0025.
Oil Drain Plug
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | HWU0107 | 🇺🇸 US | View on Amazon |
This table covers the drain plugs in the oil pan.
This group shows a single part: REIN HWU0107.
Oil Filter
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP | G7062 | 🇺🇸 US | OE# 642 180 00 09 | View on Amazon |
| PRO-TEC | PXL57062 | 🇺🇸 US | View on Amazon | |
| PUROLATOR | L25646 | 🇺🇸 US | Class: C | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MANN Popular | HU821X | 🇺🇸 US | Includes Gasket / Seal(s) | View on Amazon |
| WIX Popular | 57062 | 🇺🇸 US | View on Amazon | |
| HASTINGS / BALDWIN | LF673 | 🇺🇸 US | View on Amazon |
This table covers the oil filters that screw onto this engine's filter mount. Typical signs include low oil pressure after a service, or a filter that will not spin off because the old gasket stayed on the block. Lube the new gasket and tighten to the spec on the box; a double-gasket install dumps the sump on the first drive.
6 Oil Filter parts for the 2021 Freightliner Sprinter 4500 come from 6 brands — FVP, PRO-TEC, PUROLATOR and 3 other brands. The "Popular" part is MANN HU821X.
The Economy section lists 3 options from FVP, PRO-TEC and PUROLATOR — the catalog's value-priced group. FVP G7062 is listed in this group.
In the Standard Replacement grade, MANN, WIX and HASTINGS / BALDWIN supply 3 parts: built to original-equipment specification. A representative part number is MANN HU821X.
Listed part numbers: MANN HU821X, FVP G7062 and PRO-TEC PXL57062, plus the other parts above.
Oil Filter Cover
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| REIN | CPL0075 | 🇺🇸 US | View on Amazon |
This table covers the Oil Filter covers.
One part is listed for the 2021 Freightliner Sprinter 4500 — REIN CPL0075.
Oil Pan
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| SPECTRA PREMIUM | MDP12A | 🇺🇸 US | Lower | View on Amazon |
This table covers the oil pans that hold the engine's oil sump.
One part is listed for the 2021 Freightliner Sprinter 4500 — SPECTRA PREMIUM MDP12A.
Buying Engine Parts for a 2021 Freightliner Sprinter 4500
On this vehicle, the engine covers the internals and hard parts that build compression and keep oil where it belongs — gaskets, bearings, camshafts, lifters, seals and timing components.
- Confirm you have the 3.0L V6 DIESEL Turbocharged engine — every part on this page is matched to it.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the seals and gaskets for anything you open up; a timing job should always include the tensioner and guides, not just the belt or chain.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Oil Filter and Oil .
Frequently Asked Questions
How many engine parts fit the 2021 Freightliner Sprinter 4500?
Our catalog currently lists 16 engine parts for the 2021 Freightliner Sprinter 4500 across 7 subcategories and 9 brands, covering the 3.0L V6 DIESEL Turbocharged engine. Each part is matched to the engine(s) it fits.
What are the signs of engine problems on a 2021 Freightliner Sprinter 4500?
Common symptoms include oil spots under the vehicle, blue or white exhaust smoke, ticking from the valvetrain, or coolant mysteriously disappearing. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What oil viscosity is listed for the 2021 Freightliner Sprinter 4500?
Oil rows on this page include SAE 5W-30 and SAE 5W-40. Confirm the engine and the weight on the filler cap before you buy — high-mileage and standard fills can differ.
What should I replace at the same time?
Where labor overlaps, replace the seals and gaskets for anything you open up; a timing job should always include the tensioner and guides, not just the belt or chain.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Freightliner Sprinter 4500 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2021 Freightliner Sprinter 4500?
Every part on this page is matched to the 3.0L V6 DIESEL Turbocharged engine. Then engine hard parts are unforgiving of guesswork — confirm the casting or engine code before ordering, because one model year can hide two different blocks. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2021 Freightliner Sprinter 4500
Engine Parts for Other Freightliner Sprinter 4500 Years
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