2008 Isuzu Ascender Cooling System Parts

Engine:
4.2L L6

The 2008 Isuzu Ascender has 104 cooling system parts with verified fitment on this page — 19 part types and 39 brands, covering the 4.2L L6 engine. Each part includes a manufacturer part number and application notes.

The cooling system system on the 2008 Isuzu Ascender keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (18 parts), Radiator (10 parts) and Temperature Sender / Sensor (9 parts). The other 16 part types cover the remaining 67 parts.

Coolant / Antifreeze

Compatible With All Colors

Brand Part Number Markets Notes Buy
PRESTONE AF3055
🇺🇸 US
Prime YellowAll Vehicles
Fitment notes — PRESTONE AF3055
Prime YellowAll VehiclesExtended Life55 GAL DrumConcentratePrime® Extended Life All Makes All Models
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Economy

Brand Part Number Markets Notes Buy
FVP Popular MV5050GAL
🇺🇸 US
Extended LifeAll Makes / All Models
Fitment notes — FVP MV5050GAL
Extended LifeAll Makes / All Models1 Gallon
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PEAK BQA1GAL
🇺🇸 US
Blue Mountain Long LifeAll Vehicle
Fitment notes — PEAK BQA1GAL
Blue Mountain Long LifeAll Vehicle1 Gallon
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PRESTONE AF3100
🇺🇸 US
Prime Yellow - All VehiclesExtended Life
Fitment notes — PRESTONE AF3100
Prime Yellow - All VehiclesExtended Life1 Gallon
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VALVOLINE 719009
🇺🇸 US
Multi-Vehicle Yellow1 Gallon
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Heavy Duty

Brand Part Number Markets Notes Buy
PRESTONE AFC12100
🇺🇸 US
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT
Fitment notes — PRESTONE AFC12100
Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT1 GAL Ready To Use 50/50
Heavy Duty & Mixed Fleet Nitrite Free Extended Life CoolantYellow Fluid Class 1 - 8
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Premium

Brand Part Number Markets Notes Buy
PRESTONE Popular AF2100
🇺🇸 US
All Vehicles10yr/300k mi
Fitment notes — PRESTONE AF2100
All Vehicles10yr/300k mi1 GallonExtended Life
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PEAK PKP1GAL
🇺🇸 US
All Vehicles Antifreeze1 Gallon
Fitment notes — PEAK PKP1GAL
All Vehicles Antifreeze1 GallonPREMIUM1 GALLON10X MORE SCALE FIGHTING INHIBITORS10 YEAR/300K MILES
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PEAK PXA1GAL
🇺🇸 US
1 GallonGlobal Lifetime
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PRESTONE AF6610
🇺🇸 US
MAX Asian Green1 Gallon
Fitment notes — PRESTONE AF6610
MAX Asian Green1 Gallon
(Type: Prediluted)
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PRESTONE AFMAX
🇺🇸 US
Max Universal1 Gallon
Fitment notes — PRESTONE AFMAX
Max Universal1 Gallon15 Year/350k Miles
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Standard Replacement

Brand Part Number Markets Notes Buy
ACDELCO Popular 105027
🇺🇸 US
DEX-Cool Extended LifeDexcool (with DE-Ionized Water) (with Bitterant) 1 Gallon
Fitment notes — ACDELCO 105027
DEX-Cool Extended LifeDexcool (with DE-Ionized Water) (with Bitterant) 1 GallonPremix1 Gallon GM Original EquipmentOrange
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VALVOLINE Popular ZXEL1
🇺🇸 US
Dex-Cool Orange1 Gallon
Fitment notes — VALVOLINE ZXEL1
Dex-Cool Orange1 GallonOAT
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FVP DEX5050GAL
🇺🇸 US
Extended Life Blend1 Gallon
Fitment notes — FVP DEX5050GAL
Extended Life Blend1 GallonOrangeOAT
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PEAK PDC1GAL
🇺🇸 US
GM DEX-Cool1 Gallon
Fitment notes — PEAK PDC1GAL
GM DEX-Cool1 GallonGM APPROVED DEX-COOL 1 GALLON
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PRESTONE AF3400
🇺🇸 US
Prime OrangeOrange Compatible
Fitment notes — PRESTONE AF3400
Prime OrangeOrange CompatibleExtended Life1 Gallon ConcentrateOAT
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PRESTONE AF850
🇺🇸 US
DEX-Cool Extended Life1 Gallon
Fitment notes — PRESTONE AF850
DEX-Cool Extended Life1 GallonOrangeOAT
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VALVOLINE 675130
🇺🇸 US
Asian Vehicle Red1 Gallon
Fitment notes — VALVOLINE 675130
Asian Vehicle Red1 GallonPOAT
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This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.

Coolant Hose / Pipe Seal

Brand Part Number Markets Notes Buy
FEL-PRO 36017
🇺🇸 US
COOLANT PIPE
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This table covers the seals at the Coolant Hose / Pipe. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Coolant Reservoir

Brand Part Number Markets Notes Buy
DORMAN 603126
🇺🇸 US
Low Fluid Sensor Not Included
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GM GENUINE 89022552
🇺🇸 US 🇨🇦 CA
Tank Kit Only
Fitment notes — GM GENUINE 89022552
Tank Kit Only
4 speed Automatic trans.Air Conditioning Front Automatic/Auxiliary Control(CJ2), FrontDual Zone Climate Control with Manual Controls (blue/Red dials only)
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GPD 2411029
🇺🇸 US
View on
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This table covers the overflow / expansion tanks that hold extra coolant.

Coolant Reservoir Cap

Brand Part Number Markets Notes Buy
GM GENUINE RC122
🇺🇸 US 🇨🇦 CA
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MOTORAD T46
🇺🇸 US
Standard
Fitment notes — MOTORAD T46
Standard
Relief Pressure 15 lbs
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This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Cooling Fan Control Module

Brand Part Number Markets Notes Buy
US MOTOR WORKS 16749
🇺🇸 US
Econo Control
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US MOTOR WORKS 16779
🇺🇸 US
Better Control
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US MOTOR WORKS 16795
🇺🇸 US
Best Control
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This table covers the Cooling Fan control modules.

Cooling System Tester Adapter

Brand Part Number Markets Notes Buy
GATES 31431
🇺🇸 US
Cooling System Pressure
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GATES 31391
🇺🇸 US
Cooling System PressureRadiator Cap
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MOTORAD 3128
🇺🇸 US
StandardRadiator Cap Adapter
Fitment notes — MOTORAD 3128
StandardRadiator Cap Adapter
Cooling System PressureRadiator Cap Adapter
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MOTORAD 3127
🇺🇸 US
Standard
Fitment notes — MOTORAD 3127
Standard
Cooling System Pressure
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This table covers the adapters used to pressure-test this cooling system.

Radiator

Economy

Brand Part Number Markets Notes Buy
GPD 2458C
🇺🇸 US
View on
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OSC 2458E
🇺🇸 US
View on
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Standard Replacement

Brand Part Number Markets Notes Buy
CSF Popular 3107
🇺🇸 US
1 RowPlastic Tank / Aluminum Core
Fitment notes — CSF 3107
1 RowPlastic Tank / Aluminum Corewith Quick-Connect Oil Cooler Fittings.
with GBE, YEA Engine
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KOYORAD Popular A2458
🇺🇸 US
View on
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AGILITY 8012458
🇺🇸 US
View on
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FVP RAD2458
🇺🇸 US
View on
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GM GENUINE 21505
🇺🇸 US 🇨🇦 CA
Drain Cock Not IncludedCore Size 27 IN X 18 1/8 IN X 7/8 IN
Fitment notes — GM GENUINE 21505
Drain Cock Not IncludedCore Size 27 IN X 18 1/8 IN X 7/8 IN
4 speed Automatic trans.Code YEA,CAXTransmission Oil CoolerAir Conditioning Front Automatic/Auxiliary Control(CJ2), FrontDual Zone Climate Control with Manual Controls (blue/Red dials only)
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OSC 2458
🇺🇸 US
View on
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SPECTRA PREMIUM CU2458
🇺🇸 US
View on
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UAC RA2458C
🇺🇸 US
Downflow
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This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.

Radiator Cap

Brand Part Number Markets Notes Buy
ACDELCO RC85
🇺🇸 US 🇨🇦 CA
GM Original Equipment
Fitment notes — ACDELCO RC85
GM Original Equipment
15 PSI
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GATES 31532
🇺🇸 US
OE Type
Fitment notes — GATES 31532
OE Type
15 psi Pressure Rating
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This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.

Radiator Fan Blade

Brand Part Number Markets Notes Buy
GM GENUINE 1580696
🇺🇸 US 🇨🇦 CA
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This table covers the Radiator Fan blades. Typical signs include chatter, streaks, or a skip at the top of the stroke. Confirm left and right lengths in the notes — they are often different.

Radiator Fan Clutch

Brand Part Number Markets Notes Buy
HAYDEN Popular 2851
🇺🇸 US
ThermalSevere Duty
Fitment notes — HAYDEN 2851
ThermalSevere Duty
Counter Clockwise
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US MOTOR WORKS Popular 22627
🇺🇸 US
Thermal
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DORMAN 622001
🇺🇸 US
View on
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FAMOUS BRAND 216034
🇺🇸 US 🇨🇦 CA
Severe Duty Thermal
Fitment notes — FAMOUS BRAND 216034
Severe Duty Thermal
Counter Clockwise
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FOUR SEASONS 46049
🇺🇸 US
Severe Duty Thermal
Fitment notes — FOUR SEASONS 46049
Severe Duty Thermal
Counter Clockwise
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FVP 22627
🇺🇸 US
Thermal
Fitment notes — FVP 22627
Thermal
Counter-Clockwise Rotation
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GM GENUINE 1540144
🇺🇸 US 🇨🇦 CA
Thermal
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ULTRA-POWER 622001
🇺🇸 US 🇨🇦 CA
View on
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This table covers the Radiator Fan clutches. Typical signs include slip at highway speed, chatter on takeoff, or a pedal that stays low. Resurface or replace the flywheel with the clutch — a heat-checked flywheel wastes the new disc.

Radiator Fan Shroud

Brand Part Number Markets Notes Buy
VARIOUS MFR GM3110151
🇺🇸 US
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This table covers the shrouds that duct air through the fan and radiator.

Radiator Hose

Brand Part Number Markets Notes Buy
ACDELCO Popular 20382S
🇺🇸 US 🇨🇦 CA
Professional / GoldMolded
Fitment notes — ACDELCO 20382S
Professional / GoldMolded
Upper
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GATES Popular 22652
🇺🇸 US
Molded
Fitment notes — GATES 22652
Molded
Upper
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ACDELCO 26398X
🇺🇸 US 🇨🇦 CA
Professional / GoldMolded
Fitment notes — ACDELCO 26398X
Professional / GoldMolded
Lower
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CONTINENTAL 62422
🇺🇸 US
Molded
Fitment notes — CONTINENTAL 62422
Molded
Upper
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CONTINENTAL 62423
🇺🇸 US
Molded
Fitment notes — CONTINENTAL 62423
Molded
Lower
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DAYCO 71078
🇺🇸 US
Curved
Fitment notes — DAYCO 71078
Curved
Upper
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DAYCO 72193
🇺🇸 US
Curved
Fitment notes — DAYCO 72193
Curved
Lower
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GATES 22651
🇺🇸 US
Molded
Fitment notes — GATES 22651
Molded
Lower
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This table covers the upper, lower and connecting hoses between radiator, engine and reservoir. Typical signs include swelling, cracks, a soft spot, or a leak at a clamp. Replace adjacent aged hoses while the system is drained — they share the same heat cycle.

Temperature Sender / Sensor

Economy

Brand Part Number Markets Notes Buy
GPD 1712673
🇺🇸 US
with 2 Terminal(s)with M10 x 1.5 Thread
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HOLSTEIN 2CTS0045
🇺🇸 US
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STANDARD MOTOR PRODUCTS TX136T
🇺🇸 US
T-Series
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UNITED MOTOR PRODUCTS CTS141
🇺🇸 US
View on
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Standard Replacement

Brand Part Number Markets Notes Buy
GM GENUINE Popular 2134233
🇺🇸 US 🇨🇦 CA
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WELLS Popular 5S8203
🇺🇸 US
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NTK EF0174
🇺🇸 US
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STANDARD MOTOR PRODUCTS TX136
🇺🇸 US
View on
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WALKER PRODUCTS 2111069
🇺🇸 US
Sensor Only
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This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.

Thermostat

Economy

Brand Part Number Markets Notes Buy
SKP SK9022131
🇺🇸 US
Includes Housing
Fitment notes — SKP SK9022131
Includes Housing
190 Degrees FahrenheitCover
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Standard Replacement

Brand Part Number Markets Notes Buy
GATES Popular 33939
🇺🇸 US
Integrated Housing Thermostat
Fitment notes — GATES 33939
Integrated Housing Thermostat
192 DegreeOE TemperatureSeal Included
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GM GENUINE Popular 1511006
🇺🇸 US 🇨🇦 CA
Includes Housing, Seals, Valve,Retainer and Pipes
Fitment notes — GM GENUINE 1511006
Includes Housing, Seals, Valve,Retainer and Pipes
Thermostat, Seal, To Water PumpThermostat Housing
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MOTORAD 413192
🇺🇸 US
Includes Housing, Seal
Fitment notes — MOTORAD 413192
Includes Housing, Seal
192 Degrees FOE Specified Temperature
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MOTORAD 413180
🇺🇸 US
Includes Housing, Thermostat, Seal
Fitment notes — MOTORAD 413180
Includes Housing, Thermostat, Seal
180 Degrees FAlternate Temperature Option
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MOTORAD 413160
🇺🇸 US
Includes Housing, Thermostat, Seal
Fitment notes — MOTORAD 413160
Includes Housing, Thermostat, Seal
160 Degrees FAlternate Temperature Option
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STANT 14659
🇺🇸 US
Integrated Thermostat Housing
Fitment notes — STANT 14659
Integrated Thermostat Housing
Temperature 187 Degreeswith Seal IncludedOE Temperature, Located On Drivers side
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This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.

Thermostat / Thermostat Housing / Water Outlet Seal

Brand Part Number Markets Notes Buy
FEL-PRO Popular 35632
🇺🇸 US
Thermostat Seal
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MAHLE / CLEVITE Popular 72141
🇺🇸 US
Molded Rubber
Fitment notes — MAHLE / CLEVITE 72141
Molded Rubber
Thermostat Seal
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APEX AWO2088
🇺🇸 US
Thermostat Seal
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GM GENUINE 1533215
🇺🇸 US 🇨🇦 CA
Water Outlet Seal
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MAHLE / CLEVITE C31883
🇺🇸 US
Molded Rubber
Fitment notes — MAHLE / CLEVITE C31883
Molded Rubber
Water Outlet Seal
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VICTOR REINZ 711347200
🇺🇸 US
Thermostat Seal
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VICTOR REINZ 711424000
🇺🇸 US
View on
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This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.

Thermostat Housing / Water Outlet

Economy

Brand Part Number Markets Notes Buy
GPD 8241559
🇺🇸 US
Includes Housing
Fitment notes — GPD 8241559
Includes Housing
Water Outlet
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Standard Replacement

Brand Part Number Markets Notes Buy
GATES CO34967
🇺🇸 US
Seal IncludedWater Outlet
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GM GENUINE 1510715
🇺🇸 US 🇨🇦 CA
Includes Outlet, Connector, Seal
Fitment notes — GM GENUINE 1510715
Includes Outlet, Connector, Seal
Water Outlet
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This table covers the housings and outlets the thermostat sits in.

Water Pump

Economy

Brand Part Number Markets Notes Buy
US MOTOR WORKS Popular US5097
🇺🇸 US
View on
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BECK/ARNLEY 1312396
🇺🇸 US
Metal Impeller
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FVP US5097
🇺🇸 US
View on
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SKP SK1307700
🇺🇸 US
View on
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WJB / INMOTION PARTS WU5097
🇺🇸 US
View on
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Standard Replacement

Brand Part Number Markets Notes Buy
GATES Popular 41122
🇺🇸 US
View on
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ACDELCO 252822
🇺🇸 US 🇨🇦 CA
GoldDoes Not Include Mount Bolts
View on
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DAYCO DP965
🇺🇸 US
Serpentine Belt Driven
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GMB 1307700
🇺🇸 US
View on
Amazon

This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.

Water Pump & Fan Clutch Assembly

Brand Part Number Markets Notes Buy
FVP 1300019
🇺🇸 US
Thermal
Fitment notes — FVP 1300019
Thermal
Counter Clockwise (Reverse) RotationSevere Duty
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GMB 1300019
🇺🇸 US
KitThermal
Fitment notes — GMB 1300019
KitThermalSevere Duty
Counter Clockwise (Reverse) Rotation
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US MOTOR WORKS MCK1050
🇺🇸 US
View on
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This table covers the Water Pump & Fan Clutch assemblies.

Water Pump Gasket

Brand Part Number Markets Notes Buy
GM GENUINE Popular 2512029
🇺🇸 US 🇨🇦 CA
(OEM Design)
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APEX AWP3180
🇺🇸 US
View on
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FEL-PRO 35704
🇺🇸 US
To Block
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MAHLE / CLEVITE K31757
🇺🇸 US
Beaded Steel
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VICTOR REINZ 711469100
🇺🇸 US
View on
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This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.

Buying Cooling System Parts for a 2008 Isuzu Ascender

On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.

  • Confirm you have the 4.2L L6 engine — every part on this page is matched to it.
  • Read the notes on each row for position, trim and spec qualifiers before you order.
  • Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
  • Cross-reference the manufacturer part number against your old part or a service-manual listing.

Start with the largest groups on this page: Coolant / Antifreeze and Radiator .

Frequently Asked Questions

How many cooling system parts fit the 2008 Isuzu Ascender?

Our catalog currently lists 104 cooling system parts for the 2008 Isuzu Ascender across 19 subcategories and 39 brands, covering the 4.2L L6 engine. Each part is matched to the engine(s) it fits.

What are the signs of cooling system problems on a 2008 Isuzu Ascender?

Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.

What should I replace at the same time?

Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.

What do the market flags (US, CA, MX) on each part mean?

They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2008 Isuzu Ascender was originally sold in the US, the safest choice is a part marked for the US market.

How do I make sure a part fits my 2008 Isuzu Ascender?

Every part on this page is matched to the 4.2L L6 engine. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.

Other Parts for the 2008 Isuzu Ascender

Cooling System Parts for Other Isuzu Ascender Years

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Manufacturer names, model designations and part numbers are used for identification and fitment reference only. AutoFactsDB is an independent catalog and is not affiliated with, endorsed by, or sponsored by any vehicle manufacturer displayed on this page.