This page lists 77 cooling system parts for the 2022 Lexus IS300, across 10 part types, covering both the 2.0L L4 Turbocharged and the 3.5L V6. Every part shows its brand, manufacturer part number and fitment notes.
On the 2022 Lexus IS300, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. 47 parts of the 77 listed are Temperature Sender / Sensor (17 parts), Coolant / Antifreeze (15 parts) and Water Pump (15 parts). The other 7 part types cover the remaining 30 parts.
The 2022 Lexus IS300 was sold with both the 2.0L L4 Turbocharged and the 3.5L V6. 22 parts fit every engine; the other 55 are engine-specific. Each part shows which engine(s) it fits.
The most listed brands for 2022 Lexus IS300 cooling system parts are BECK/ARNLEY (7 parts), AISIN (6 parts) and GPD (6 parts), plus 30 more brands. Quality grades include Standard Replacement, Economy and Premium.
15 parts on this 2022 Lexus IS300 page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including PRESTONE AF2100 (Coolant / Antifreeze) and DENSO 2219578 (Radiator). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2022 IS300 engines | AF3055 | 🇺🇸 US 🇨🇦 CA | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PEAK Fits: all 2022 IS300 engines | BQA1GAL | 🇺🇸 US 🇨🇦 CA | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| PRESTONE Fits: all 2022 IS300 engines | AF3100 | 🇺🇸 US 🇨🇦 CA | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| VALVOLINE Fits: all 2022 IS300 engines | 719009 | 🇺🇸 US 🇨🇦 CA | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2022 IS300 engines | AF2100 | 🇺🇸 US 🇨🇦 CA | All Vehicles10yr/300k mi | View on Amazon |
| PEAK Fits: all 2022 IS300 engines | PKP1GAL | 🇺🇸 US 🇨🇦 CA | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK Fits: all 2022 IS300 engines | PXA1GAL | 🇺🇸 US 🇨🇦 CA | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE Fits: all 2022 IS300 engines | AF6210 | 🇺🇸 US 🇨🇦 CA | MAX Original EquipmentAsian Red/Pink | View on Amazon |
| PRESTONE Fits: all 2022 IS300 engines | AFMAX | 🇺🇸 US 🇨🇦 CA | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular Fits: all 2022 IS300 engines | ACT002 | 🇺🇸 US 🇨🇦 CA | PinkHOAT | View on Amazon |
| VALVOLINE Popular Fits: all 2022 IS300 engines | 675130 | 🇺🇸 US 🇨🇦 CA | Asian Vehicle Red1 Gallon | View on Amazon |
| BECK/ARNLEY Fits: all 2022 IS300 engines | 2521502 | 🇺🇸 US 🇨🇦 CA | Premium Extra Life Pink | View on Amazon |
| BECK/ARNLEY Fits: all 2022 IS300 engines | 2521002 | 🇺🇸 US 🇨🇦 CA | Premium Red | View on Amazon |
| PEAK Fits: all 2022 IS300 engines | PAR1GAL | 🇺🇸 US 🇨🇦 CA | OET Asian Extended Life Red1 Gallon | View on Amazon |
| PENTOSIN Fits: all 2022 IS300 engines | 8115209 | 🇺🇸 US 🇨🇦 CA | Pentofrost A41 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
15 Coolant / Antifreeze parts for the 2022 Lexus IS300 come from 6 brands — PRESTONE, PEAK, VALVOLINE and 3 other brands. The "Popular" part is PRESTONE AF2100. Every part fits both the 2.0L L4 Turbocharged and the 3.5L V6.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 3 options from PEAK, PRESTONE and VALVOLINE — the catalog's value-priced group. PEAK BQA1GAL is listed in this group.
In the Premium grade, PRESTONE and PEAK supply 5 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, BECK/ARNLEY, AISIN, VALVOLINE and 2 other brands supply 6 parts: built to original-equipment specification. A representative part number is AISIN ACT002.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| CALORSTAT Fits: all 2022 IS300 engines | RC0145 | 🇺🇸 US 🇨🇦 CA | Attachment Type: Threaded | View on Amazon |
| GATES Fits: all 2022 IS300 engines | 31541 | 🇺🇸 US 🇨🇦 CA | OE TypeThreaded (Closed System) - (SAE Range 18-20 psi) | View on Amazon |
| MOTORAD Fits: all 2022 IS300 engines | T51 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
3 Coolant Reservoir Cap parts are listed for the 2022 Lexus IS300, from CALORSTAT, GATES and MOTORAD. All of them fit every engine offered in the 2022 IS300.
This group includes CALORSTAT RC0145, GATES 31541 and MOTORAD T51.
Cooling Fan Control Module
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| ACKOJA Fits: 2.0L L4 Turbocharged | A70790004 | 🇺🇸 US 🇨🇦 CA | From 09/2020with OE No. 8925726020 | View on Amazon |
| STANDARD MOTOR PRODUCTS Fits: 3.5L V6 | RY1890 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the Cooling Fan control modules.
2 Cooling Fan Control Module parts are listed for the 2022 Lexus IS300, from ACKOJA and STANDARD MOTOR PRODUCTS.
Listed part numbers: ACKOJA A70790004 and STANDARD MOTOR PRODUCTS RY1890.
Radiator
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD Fits: 2.0L L4 Turbocharged | 13912C | 🇺🇸 US 🇨🇦 CA | Auxiliary | View on Amazon |
| GPD Fits: 2.0L L4 Turbocharged | 13612C | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GPD Fits: 3.5L V6 | 13776C | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DENSO Popular Fits: 2.0L L4 Turbocharged | 2219578 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| TYC Popular Fits: 2.0L L4 Turbocharged | 13612 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| OSC Fits: 2.0L L4 Turbocharged | 13612 | 🇺🇸 US 🇨🇦 CA | MAIN RADIATOR | View on Amazon |
| TYC Fits: 3.5L V6 | 13776 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UAC Fits: all 2022 IS300 engines | RA13612C | 🇺🇸 US 🇨🇦 CA | Downflow | View on Amazon |
This table covers the radiators that dump engine heat to airflow through the core. Typical signs include overheating in traffic, a wet core, or coolant that disappears with no puddle. Replace the cap if it cannot hold the rated pressure, and bleed the system after the swap.
8 Radiator parts for the 2022 Lexus IS300 come from 5 brands — GPD, TYC, DENSO and 2 other brands. The "Popular" part is DENSO 2219578. 1 part fits every engine; the other 7 are engine-specific.
The Economy section: 3 options from GPD. GPD 13912C is listed in this group.
Standard Replacement: 5 parts, from TYC, DENSO, OSC and 1 other brand. A representative part number is DENSO 2219578.
Listed part numbers: DENSO 2219578, GPD 13912C and GPD 13612C, plus the other parts above.
Radiator Fan Assembly
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 3.5L V6 | 620498 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GPD Fits: 3.5L V6 | 2812007 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FOUR SEASONS Fits: 3.5L V6 | 76335 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UAC Fits: 3.5L V6 | FA50658C | 🇺🇸 US 🇨🇦 CA | Radiator-Condenser Fan Assembly | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| TECHPRO Fits: 2.0L L4 Turbocharged | LX3115149 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
This table covers the fan assemblies (and clutches, where listed) that pull air through the radiator.
5 Radiator Fan Assembly parts are listed for the 2022 Lexus IS300, from DORMAN, GPD, FOUR SEASONS and 2 other brands.
Economy: 2 parts, from DORMAN and GPD. A representative part number is DORMAN 620498.
The Standard Replacement section: 2 options from FOUR SEASONS and UAC. FOUR SEASONS 76335 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
This group includes DORMAN 620498, GPD 2812007 and FOUR SEASONS 76335 and the remaining parts above.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| GPD Fits: 2.0L L4 Turbocharged | 1712514 | 🇺🇸 US 🇨🇦 CA | with 2 Terminal(s)with M12 x 1.5 Thread | View on Amazon |
| GPD Fits: 3.5L V6 | 1814519 | 🇺🇸 US 🇨🇦 CA | Connector Gender: Female | View on Amazon |
| HOLSTEIN Fits: 2.0L L4 Turbocharged | 2CTS0051 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| UNITED MOTOR PRODUCTS Fits: 2.0L L4 Turbocharged | CTS25 | 🇺🇸 US 🇨🇦 CA | Rectangular Connector | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular Fits: 3.5L V6 | THSAZ8003 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DELPHI Popular Fits: 2.0L L4 Turbocharged | TS10289 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| STANDARD MOTOR PRODUCTS Popular Fits: 2.0L L4 Turbocharged | TX40 | 🇺🇸 US 🇨🇦 CA | Rectangular Connector2 Terminal | View on Amazon |
| STANDARD MOTOR PRODUCTS Popular Fits: 3.5L V6 | TX273 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| ACDELCO Fits: 2.0L L4 Turbocharged | D583 | 🇺🇸 US 🇨🇦 CA | Gold | View on Amazon |
| AISIN Fits: 2.0L L4 Turbocharged | THSAZ8001 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| BECK/ARNLEY Fits: 2.0L L4 Turbocharged | 1581585 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| BECK/ARNLEY Fits: 3.5L V6 | 1581802 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DELPHI Fits: 3.5L V6 | TS10626 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| DENSO Fits: 2.0L L4 Turbocharged | 1931000 | 🇺🇸 US 🇨🇦 CA | Engine Coolant Temperature Sensor | View on Amazon |
| WALKER PRODUCTS Fits: 2.0L L4 Turbocharged | 2111060 | 🇺🇸 US 🇨🇦 CA | Sensor Only | View on Amazon |
| WALKER PRODUCTS Fits: 3.5L V6 | 2112012 | 🇺🇸 US 🇨🇦 CA | Sensor Only | View on Amazon |
| WELLS Fits: 3.5L V6 | 5S15288 | 🇺🇸 US 🇨🇦 CA | Located in Engine | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
17 Temperature Sender / Sensor parts for the 2022 Lexus IS300 come from 11 brands — GPD, AISIN, DELPHI and 8 other brands. The "Popular" part is AISIN THSAZ8003.
The Economy section: 4 options from GPD, HOLSTEIN and UNITED MOTOR PRODUCTS. GPD 1712514 is listed in this group.
Standard Replacement: 13 parts, from AISIN, DELPHI, STANDARD MOTOR PRODUCTS and 5 other brands. A representative part number is AISIN THSAZ8003.
Thermostat
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular Fits: all 2022 IS300 engines | THT029 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| JAPANESE OE Popular Fits: 3.5L V6 | WHTYL87 | 🇺🇸 US 🇨🇦 CA | TamaIncludes Housing | View on Amazon |
| BECK/ARNLEY Fits: 2.0L L4 Turbocharged | 1430971 | 🇺🇸 US 🇨🇦 CA | Outer (Toward Lower Radiator Coolant Hose)Temperature: 82C/180F | View on Amazon |
| BECK/ARNLEY Fits: 3.5L V6 | 1430976 | 🇺🇸 US 🇨🇦 CA | TEMPERATURE 86C/188F | View on Amazon |
| FOUR SEASONS Fits: 3.5L V6 | 86320 | 🇺🇸 US 🇨🇦 CA | Includes Housing | View on Amazon |
| MAHLE / CLEVITE Fits: 3.5L V6 | TI37987D | 🇺🇸 US 🇨🇦 CA | Integral Thermostat | View on Amazon |
| MOTORAD Fits: 2.0L L4 Turbocharged | 1064172 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
| MOTORAD Fits: 2.0L L4 Turbocharged | 1065180 | 🇺🇸 US 🇨🇦 CA | Standard | View on Amazon |
| MOTORAD Fits: 3.5L V6 | 1046188 | 🇺🇸 US 🇨🇦 CA | Includes Housing, Sensor, Seal | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
9 Thermostat parts are listed for the 2022 Lexus IS300, from MOTORAD, BECK/ARNLEY, AISIN and 3 other brands. AISIN THT029 carries the "Popular" badge. 1 part fits every engine; the other 8 are engine-specific.
Part numbers include AISIN THT029, JAPANESE OE WHTYL87 and BECK/ARNLEY 1430971, among others listed above.
Thermostat / Thermostat Housing / Water Outlet Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MAHLE / CLEVITE Fits: 3.5L V6 | C33835 | 🇺🇸 US 🇨🇦 CA | Molded Rubber | View on Amazon |
| MAHLE / CLEVITE Fits: 3.5L V6 | C33837 | 🇺🇸 US 🇨🇦 CA | Engine Coolant Outlet O-RingMolded Rubber | View on Amazon |
This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
2 Thermostat / Thermostat Housing / Water Outlet Seal parts for the 2022 Lexus IS300 come from MAHLE / CLEVITE.
This group includes MAHLE / CLEVITE C33835 and MAHLE / CLEVITE C33837.
Thermostat Housing / Water Outlet
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: 2.0L L4 Turbocharged | CH3174 | 🇺🇸 US 🇨🇦 CA | Fits OuterThermostat Housing | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
One part is listed for the 2022 Lexus IS300 — MOTORAD CH3174.
Water Pump
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| BECK/ARNLEY Fits: 3.5L V6 | 1312538 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FVP Fits: 3.5L V6 | US8150 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| SKP Fits: 3.5L V6 | SK1703020 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| US MOTOR WORKS Fits: 2.0L L4 Turbocharged | US8174 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| US MOTOR WORKS Fits: 3.5L V6 | US8150 | 🇺🇸 US 🇨🇦 CA | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular Fits: 2.0L L4 Turbocharged | WPT203 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| AISIN Popular Fits: 3.5L V6 | WPT808 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GATES Popular Fits: 3.5L V6 | 43424 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB Popular Fits: 2.0L L4 Turbocharged | 1703030 | 🇺🇸 US 🇨🇦 CA | Primary Pump | View on Amazon |
| DAYCO Fits: 2.0L L4 Turbocharged | DP1872 | 🇺🇸 US 🇨🇦 CA | Serpentine Belt Driven | View on Amazon |
| DAYCO Fits: 3.5L V6 | DP2182 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| FOUR SEASONS Fits: all 2022 IS300 engines | 89088 | 🇺🇸 US 🇨🇦 CA | AuxiliaryIntercooler Pump | View on Amazon |
| GATES Fits: 2.0L L4 Turbocharged | 41217 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| GMB Fits: 3.5L V6 | 1703020 | 🇺🇸 US 🇨🇦 CA | View on Amazon | |
| NISSENS Fits: all 2022 IS300 engines | 833809 | 🇺🇸 US 🇨🇦 CA | AuxiliaryIntercooler Pump | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
15 Water Pump parts are listed for the 2022 Lexus IS300, from US MOTOR WORKS, AISIN, GATES and 7 other brands. AISIN WPT203 carries the "Popular" badge. 2 parts fit every engine; the other 13 are engine-specific.
Economy: 5 parts, from US MOTOR WORKS, BECK/ARNLEY, FVP and 1 other brand. A representative part number is BECK/ARNLEY 1312538.
The Standard Replacement section: 10 options from AISIN, GATES, GMB and 3 other brands. AISIN WPT203 is listed in this group.
Buying Cooling System Parts for a 2022 Lexus IS300
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Temperature Sender / Sensor and Coolant / Antifreeze .
Frequently Asked Questions
How many cooling system parts fit the 2022 Lexus IS300?
Our catalog currently lists 77 cooling system parts for the 2022 Lexus IS300 across 10 subcategories and 33 brands, covering both the 2.0L L4 Turbocharged and the 3.5L V6. Each part is matched to the engine(s) it fits.
Do cooling system parts differ between 2022 Lexus IS300 engines?
Some do. 22 parts fit every engine; the other 55 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.
What are the signs of cooling system problems on a 2022 Lexus IS300?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2022 Lexus IS300 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2022 Lexus IS300?
First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2022 Lexus IS300
Cooling System Parts for Other Lexus IS300 Years
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