26 Cooling system parts are listed for the 2021 Nissan NP300, in 9 part types, covering both the 2.5L L4 and the 2.5L L4 DIESEL Turbocharged. Each one has a brand, a manufacturer part number and notes that say where it fits.
The cooling system system on the 2021 Nissan NP300 keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses. The largest groups are Coolant / Antifreeze (11 parts), Water Pump (4 parts) and Thermostat Housing / Water Outlet (3 parts). The other 6 part types cover the remaining 8 parts.
The 2021 Nissan NP300 was sold with both the 2.5L L4 and the 2.5L L4 DIESEL Turbocharged. 17 parts fit every engine; the other 9 are engine-specific. Each part shows which engine(s) it fits.
The most listed brands for 2021 Nissan NP300 cooling system parts are MOTORAD (6 parts), PRESTONE (5 parts) and PEAK (4 parts), plus 7 more brands. Quality grades include Economy, Premium and Standard Replacement.
3 parts on this 2021 Nissan NP300 page carry a "Popular" badge — the source catalog's flag for options frequently chosen for this vehicle — including PRESTONE AF3100 (Coolant / Antifreeze) and PRESTONE AF2100 (Coolant / Antifreeze). Click any part number to see every vehicle that part fits.
Coolant / Antifreeze
Compatible With All Colors
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2021 NP300 engines | AF3055 | 🇲🇽 MX | Prime YellowAll Vehicles | View on Amazon |
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2021 NP300 engines | AF3100 | 🇲🇽 MX | Prime Yellow - All VehiclesExtended Life | View on Amazon |
| PEAK Fits: all 2021 NP300 engines | BQA1GAL | 🇲🇽 MX | Blue Mountain Long LifeAll Vehicle | View on Amazon |
| VALVOLINE Fits: all 2021 NP300 engines | 719009 | 🇲🇽 MX | Multi-Vehicle Yellow1 Gallon | View on Amazon |
Heavy Duty
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Fits: all 2021 NP300 engines | AFC12100 | 🇲🇽 MX | Command Nitrite Free Extended Life CoolantYellow Nitrite Free OAT | View on Amazon |
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| PRESTONE Popular Fits: all 2021 NP300 engines | AF2100 | 🇲🇽 MX | All Vehicles10yr/300k mi | View on Amazon |
| PEAK Fits: all 2021 NP300 engines | PKP1GAL | 🇲🇽 MX | All Vehicles Antifreeze1 Gallon | View on Amazon |
| PEAK Fits: all 2021 NP300 engines | PXA1GAL | 🇲🇽 MX | Global Lifetime1 Gallon | View on Amazon |
| PRESTONE Fits: all 2021 NP300 engines | AFMAX | 🇲🇽 MX | Max Universal1 Gallon | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AISIN Popular Fits: all 2021 NP300 engines | ACB003 | 🇲🇽 MX | BlueHOAT | View on Amazon |
| PEAK Fits: all 2021 NP300 engines | PAB1GAL | 🇲🇽 MX | OET Asian Extended Life Blue1 Gallon | View on Amazon |
This table covers the engine coolants and antifreeze formulations specified for this cooling system. Typical signs include a rising temperature gauge, rusty or sludged coolant, or a heater that blows cold. Use the chemistry named in the notes. Mixing silicate, OAT and HOAT formulas can gel in the radiator.
11 Coolant / Antifreeze parts for the 2021 Nissan NP300 come from 4 brands — PRESTONE, PEAK, VALVOLINE and 1 other brand. The "Popular" part is PRESTONE AF3100. Every part fits both the 2.5L L4 and the 2.5L L4 DIESEL Turbocharged.
In the Compatible With All Colors grade, PRESTONE supplies 1 part: grouped under the catalog's "Compatible With All Colors" designation — the notes column spells out what sets them apart. A representative part number is PRESTONE AF3055.
The Economy section lists 3 options from PRESTONE, PEAK and VALVOLINE — the catalog's value-priced group. PRESTONE AF3100 is listed in this group.
In the Heavy Duty grade, PRESTONE supplies 1 part: rated for severe service. A representative part number is PRESTONE AFC12100.
In the Premium grade, PRESTONE and PEAK supply 4 parts: a step above OE specification in materials, tolerances or warranty terms. A representative part number is PRESTONE AF2100.
In the Standard Replacement grade, AISIN and PEAK supply 2 parts: built to original-equipment specification. A representative part number is AISIN ACB003.
Coolant Reservoir Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: all 2021 NP300 engines | T152 | 🇲🇽 MX | Standard | View on Amazon |
This table covers the caps on the overflow / expansion tank. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
One part is listed for the 2021 Nissan NP300 — MOTORAD T152.
Radiator Cap
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: all 2021 NP300 engines | T18R | 🇲🇽 MX | Standard | View on Amazon |
This table covers the caps that hold system pressure at the radiator or reservoir neck. Typical signs include a leak at the neck, a cap that will not hold pressure, or a missing tether. Match the pressure rating or thread in the notes — radiator, reservoir and fuel caps are not interchangeable.
This group shows a single part: MOTORAD T18R.
Temperature Sender / Sensor
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| STANDARD MOTOR PRODUCTS Fits: all 2021 NP300 engines | TX78T | 🇲🇽 MX | T-SeriesBlack | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| STANDARD MOTOR PRODUCTS Fits: all 2021 NP300 engines | TX78 | 🇲🇽 MX | Includes O-Ringblack | View on Amazon |
This table covers the senders that report coolant temperature to the gauge or ECU. Typical signs include a gauge that sits on empty or overheat, or a lamp that does not match what the engine is doing. Rule out the cluster and the wiring before replacing the sender.
2 Temperature Sender / Sensor parts for the 2021 Nissan NP300 come from STANDARD MOTOR PRODUCTS. Every part fits both the 2.5L L4 and the 2.5L L4 DIESEL Turbocharged.
The Economy section: 1 option from STANDARD MOTOR PRODUCTS. STANDARD MOTOR PRODUCTS TX78T is listed in this group.
Standard Replacement: 1 part, from STANDARD MOTOR PRODUCTS. A representative part number is STANDARD MOTOR PRODUCTS TX78.
This group includes STANDARD MOTOR PRODUCTS TX78T and STANDARD MOTOR PRODUCTS TX78.
Thermostat
Premium
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: all 2021 NP300 engines | 7427180 | 🇲🇽 MX | Fail-SafeIncludes seal | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: all 2021 NP300 engines | 427180 | 🇲🇽 MX | Includes Seal | View on Amazon |
This table covers the thermostats that open the coolant circuit at the specified temperature. Typical signs include slow warm-up, a gauge that climbs in traffic, or heat that never quite arrives. Replace the housing gasket with the thermostat and bleed the system so a trapped air pocket does not cook the new part.
MOTORAD supplies both parts for the 2021 Nissan NP300. All of them fit every engine offered in the 2021 NP300.
The Premium section: 1 option from MOTORAD. MOTORAD 7427180 is listed in this group.
The Standard Replacement section: 1 option from MOTORAD. MOTORAD 427180 is listed in this group.
This group includes MOTORAD 7427180 and MOTORAD 427180.
Thermostat / Thermostat Housing / Water Outlet Seal
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AJUSA Fits: 2.5L L4 | 01291700 | 🇲🇽 MX | Water Outlet Gasket | View on Amazon |
This table covers the seals at the thermostat housing and water outlet. Typical signs include a wet housing, a drip after sitting, or fluid flung off a rotating shaft. Fix the surface the seal rides on. A new seal on a grooved shaft will leak again.
This group shows a single part: AJUSA 01291700.
Thermostat Housing / Water Outlet
Economy
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| DORMAN Fits: 2.5L L4 | 9025222 | 🇲🇽 MX | Thermostat Housing | View on Amazon |
Standard Replacement
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: 2.5L L4 | CH5222 | 🇲🇽 MX | Includes Gasket | View on Amazon |
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| MOTORAD Fits: 2.5L L4 DIESEL Turbocharged | CH5222 | 🇲🇽 MX | Includes Gasket | View on Amazon |
This table covers the housings and outlets the thermostat sits in.
3 Thermostat Housing / Water Outlet parts are listed for the 2021 Nissan NP300, from MOTORAD and DORMAN.
Economy: 1 part, from DORMAN. A representative part number is DORMAN 9025222.
The Standard Replacement section: 1 option from MOTORAD. MOTORAD CH5222 is listed in this group.
1 ungrouped part is not assigned to a grade, with the same engine-level match.
Part numbers include DORMAN 9025222 and MOTORAD CH5222, among others listed above.
Water Pump
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| FVP Fits: 2.5L L4 | US8212 | 🇲🇽 MX | View on Amazon | |
| FVP Fits: 2.5L L4 DIESEL Turbocharged | US8998 | 🇲🇽 MX | View on Amazon | |
| US MOTOR WORKS Fits: 2.5L L4 | US8212 | 🇲🇽 MX | View on Amazon | |
| US MOTOR WORKS Fits: 2.5L L4 DIESEL Turbocharged | US8998 | 🇲🇽 MX | View on Amazon |
This table covers the pumps that circulate coolant through the block and radiator. Typical signs include coolant at the weep hole, pulley play, or a growl from the front of the engine. Replace the thermostat and refill with the specified coolant whenever the pump comes off.
4 Water Pump parts are listed for the 2021 Nissan NP300, from FVP and US MOTOR WORKS.
Listed part numbers: FVP US8212 and FVP US8998, plus the other parts above.
Water Pump Gasket
| Brand | Part Number | Markets | Notes | Buy |
|---|---|---|---|---|
| AJUSA Fits: 2.5L L4 | 01597100 | 🇲🇽 MX | View on Amazon |
This table covers the gaskets between the water pump and the block or housing. Typical signs include seepage at the joint, a burnt-oil smell, or a leak that appears only after a long drive. Clean both flanges and torque in the sequence the notes or the manual call for.
This group shows a single part: AJUSA 01597100.
Buying Cooling System Parts for a 2021 Nissan NP300
On this vehicle, the cooling system system keeps operating temperature in the narrow band the engine was designed for, from radiator and water pump to thermostat and hoses.
- Match the engine first. Some cooling system parts fit every engine; others are engine-specific. Each row shows which engine(s) it fits.
- Read the notes on each row for position, trim and spec qualifiers before you order.
- Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
- Cross-reference the manufacturer part number against your old part or a service-manual listing.
Start with the largest groups on this page: Coolant / Antifreeze and Water Pump .
Frequently Asked Questions
How many cooling system parts fit the 2021 Nissan NP300?
Our catalog currently lists 26 cooling system parts for the 2021 Nissan NP300 across 9 subcategories and 10 brands, covering both the 2.5L L4 and the 2.5L L4 DIESEL Turbocharged. Each part is matched to the engine(s) it fits.
Do cooling system parts differ between 2021 Nissan NP300 engines?
Some do. 17 parts fit every engine; the other 9 are engine-specific. Each row (and the filter at the top) shows which. If you're unsure which engine you have, check the emissions label under the hood or the 8th character of your VIN.
What are the signs of cooling system problems on a 2021 Nissan NP300?
Common symptoms include a rising temperature gauge in traffic, sweet-smelling steam, crusty deposits around hose clamps, or a heater that blows cold. If you notice any of these, identify the affected subcategory above and cross-reference the part numbers listed.
What should I replace at the same time?
Where labor overlaps, replace the thermostat and refill with fresh coolant whenever you change a water pump or radiator; original hoses on an older vehicle are on borrowed time.
What do the market flags (US, CA, MX) on each part mean?
They show the market for which the manufacturer published application data for that part — where the vehicle was first sold, not where the part was made. If your 2021 Nissan NP300 was originally sold in the US, the safest choice is a part marked for the US market.
How do I make sure a part fits my 2021 Nissan NP300?
First match the engine — each row shows which engine(s) the part fits. Then replace coolant with the exact specification the manufacturer calls for — mixing chemistries can gel and block small passages. The notes column carries position and trim qualifiers where they apply.
Other Parts for the 2021 Nissan NP300
Cooling System Parts for Other Nissan NP300 Years
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